The subjective experience of subjects diagnosed with celiac disease in adulthood

Introduction

Celiac disease is estimated to affect between 1 in 100 and 1 in 300 Caucasian subjects. Many quantitative studies have explored the issues encountered by these subjects; however, few studies have addressed the subjective and experiential dimensions of celiac disease.

A correlation between sickness or injury within two weeks,chronic diseases and fatigue among adults aged 18–45 years

To investigate the prevalence of fatigue, the relationship between sickness or injury within two weeks, chronic diseases and fatigue among adults aged 18–45 years. Thousand five hundred and seventy nine individuals were included in this cross-sectional study. The Chalder Fatigue Scale (CFS) was used to assess fatigue defined as CFS score ≥4. The prevalence of fatigue was 25% in this study. Our results showed that only sickness or injury within two weeks (odds ratio [OR]: 2.440) and chronic diseases (OR: 1.727) were significantly related to fatigue. Moreover, their ORs for fatigue remained the same in all models (binary logistic regression models with adjusting for demographic and health-related characteristics one by one). In conclusion, fatigue was prevalent among adults aged 18–45 years. Sickness or injury within two weeks and chronic diseases were the risk factors for fatigue independent of demographic and health-related characteristics.     

Object decision test (BORB): normative data for the adult Quebec population and performance in Alzheimer’s disease and the semantic variant of primary progressive aphasia

Object decision (OD) test is one subtest of the Birmingham Object Recognition Battery (BORB). It is useful for differential diagnosis among several neurodegenerative diseases. However, normative data provided with this battery count on very few subjects and do not control for the effect of age, which limits interpretability. The purpose of Study 1 was to provide normative data for the OD test of the BORB (version A—hard). The objectives of Study 2 were to establish the diagnostic validity of this task and predictive validity of the normative data in the case of the semantic variant of primary progressive aphasia (svPPA) and Alzheimer’s disease (AD).Based on multiple linear regressions, equations to calculate Z-scores corrected for age were provided for 130 participants aged from 47 to 89 years. Performance of 20 healthy participants was compared to that of 14 individuals with svPPA and 18 with AD. After controlling for confounders, participants with svPPA had a lower total score than controls and AD participants. AD participants had a poorer performance than controls only when chimeric objects were considered. Among those with a deficit on the total score of the test, 94% (17/18, including 12 with svPPA) were correctly identified as having a pathological condition (svPPA or AD). This test could help refine differential diagnosis between svPPA and AD patients, especially before the deficits of episodic memory show up.     

改变因症就诊的医疗模式搞好慢性呼吸疾病的防控

本文简单介绍了各种慢性呼吸疾病的特点、重要性、病因和发病机理,重点阐述认真搞好三级预防是有效防控慢性呼吸疾病的基础,而目前我国慢性呼吸疾病医疗服务模式是因症就诊,这种医疗服务模式不利于慢性呼吸疾病的管理和控制,必须尽快改变。     

肾血管病的经皮介入治疗：争议与共识

由于近十年来经皮介入治疗技术的巨大进展,肾血管病（renovascular disease,RVD）患者中接受经皮肾动脉成形治疗的数量迅速增加,已作为纠正严重肾动脉狭窄的首选措施逐步被接受。但目前对粥样硬化性肾动脉狭窄尚无公认的最优治疗,选择经皮介入重建肾动脉血流还是单纯药物保守治疗在学术界尚有争议。现系统评述目前临床...     

肝脾CT值分析在非酒精性脂肪肝诊断中的应用

探讨肝脾CT值分析在非酒精性脂肪肝中诊断及严重程度的关系。对163例临床明确诊断的非酒精性脂肪肝患者,分别根据肝脏cT值、肝脾CT值比值及肝脾CT值差值进行分组。结果三种评价方法对重度非酒精性脂肪肝均有较高的灵敏度及特异度,轻度非酒精性脂肪肝样本中出现28例肝脾CT比值〉1,肝脾值差值与肝脾CT值比值在对脂肪肝严重程度...     

儿童缺血性脑病的诊治策略

结合国内外文献资料,从儿童缺血性脑病的病因、临床表现、影像学特点、治疗方式及疗效等方面着手,进行分析和比较,加深医患对儿童缺血性脑病的了解,同时为该类疾病的临床诊断与治疗思路提供借鉴。     

应该发挥医院、医生在慢性病预防中的作用

从必要性分析、可行性分析、预防效果分析及存在的问题等方面探讨在我国必须要发挥医院、医生在慢性病预防中的作用,只有整合医疗资源与疾病预防控制资源,才能更好地预防慢性病。     

心理干预对急性冠脉综合征伴抑郁患者应对方式的影响

为了解心理干预对急性冠脉综合征（ACS）伴抑郁患者应对方式的影响,对42名ACS伴抑郁患者随机分为干预组和对照组,在入组时、入组3月后和6月后分别进行HAD（d）、MCMQ测评。结果显示入组3月后和6月后,干预组HAD（d）总分、回避因子分、屈服因子分较对照组降低,面对因子分较对照组升高,与入组时相比干预组HAD（d）...