Utility of the Multidimensional Health Profile—Psychosocial Functioning Scales (MHP-P) for Assessing Psychosocial Adjustment in Gastric Bypass Surgery Patients

This study examined the utility of the Multidimensional Health Profile—Psychosocial Functioning (MHP-P) for the preoperative assessment of gastric bypass surgery (GBS) applicants. The MHP-P, a 58-item screening inventory that assesses 4 psychosocial areas relevant to health (mental health, life stress, social resources, and coping skills), was administered to 449 morbidly obese patients who were being considered for GBS. Data were compared with the results of a much more lengthy assessment procedure involving a 273-item comprehensive biographical and medical history interview, the MMPI-2, the Basic Personality Inventory, and the Beck Depression Inventory. The 17 measures of the MHP-P showed highly significant correlations with other measures considered to be of relevance in GBS outcome, confirming the utility of the MHP-P as a cost-effective procedure for use in this clinical medical setting.     

冠状动脉搭桥术后再狭窄研究的思考

冠状动脉搭桥术(CABG)是目前外科治疗冠心病的成熟、定型的手术方法,但术后再狭窄影响了病人的远期疗效,其研究也越来越受到人们重视。随着生物医学模式向生物心理社会医学模式的转变,研究者对CABG术后再狭窄也有了更深入的认识,更加注重整体性、动态化和系统最优化。试用系统论方法探讨CABG术后再狭窄的防治。     

冠状动脉慢性闭塞病变的治疗决策

虽然越来越多的冠状动脉慢性闭塞病变正在采用经皮冠状动脉介入治疗,但其临床疗效是否能够与冠状动脉旁路移植术相媲美,目前尚不能妄下结论。经皮冠状动脉介入治疗和冠状动脉旁路移植术在冠状动脉慢性闭塞病变的治疗中各有其最佳适应证,相互之间是不可替代、但可以互补的。而且联合治疗、杂交技术和微创治疗是其未来发展方向。     

稳定性冠心病何时需要PCI

目前稳定性冠心病通行的治疗策略是药物治疗的同时常规作冠脉造影,如果病变严重,则尽可能地作介入治疗。但最近COURAGE试验结果的公布,证实介入治疗仅可以缓解症状,但不能改善预后。因此,我们要对PCI在稳定性冠心病中的作用和定位重新进行思考。     

体外循环在气管内肿瘤治疗中的应用与思考

近年来体外循环技术已经不仅仅用于心脏手术,还广泛应用于非心脏手术。应用体外循环技术切除气管内肿瘤比常规气管插管全身麻醉扩大了手术适应征,但是也附加了相应的手术并发症。临床医生应有系统的观点,以循证医学模式为指导,坚持以人为本,个性化地将这项技术应用于患者。     

非ST段抬高急性冠脉综合征药物治疗规范化分析

回顾性分析我院收治的129例非ST段抬高急性冠脉综合征患者的临床资料。对比在非ST段抬高急性冠脉综合征诊治上与最新指南的差距,找出改进措施。结果表明我院的临床实践与最新指南存在较大差距,在强化抗栓,调脂治疗,B受体阻滞剂及血管紧张素转换酶抑制荆类药物使用上均有待提高。今后应采取更加积极的措施,规范用药,以达到更好的预后和转归效果。     

β受体阻滞剂是冠心病中的重要一线治疗药物

冠心病的治疗包括三个层面:血管重建治疗解决局部狭窄;改善生活方式是基础;全面合理的药物治疗是核心.而β受体阻滞剂又是重要的一线治疗药物,不仅能降低动脉粥样硬化及急性冠脉综合征的发生发展,还能有效预防、缓解心绞痛发生,改善梗死后左室重构和心功能;降低心肌再梗死率,降低心性猝死和病死率.临床上应用β受体阻滞剂的时机和剂量非常重要.     

Marital Status and Outcome in Patients with Coronary Heart Disease

The purpose of this study was to examine the relationship of marital status to health outcomes in 818 post-MI, coronary artery bypass surgery, and angioplasty patients (651 males, 157 females) from seven Northern California hospitals who completed 12 months of a nurse-managed, home-based multifactorial risk reduction program. Compared to married patients, nonmarried patients were significantly less likely to complete the program than married patients, more likely to smoke at baseline, and drank significantly less alcohol at baseline. At 12 months there were no significant differences between married and nonmarried groups on smoking cessation rates, HDL, LDL, triglycerides, or exercise treadmill test results. When patients were categorized as married, divorced, separated, widowed, or single, similar results were found for the analyses using two groups (married versus nonmarried), with the following exceptions. Separated patients were significantly less likely to quit smoking. In addition, separated patients showed significantly higher rates of starting (and continuing) to smoke during the time following their MI. Mortality was not significantly different between married and unmarried patients. Implications for intervention with separated patients and the importance of assessing both marital status and marital quality are discussed.     

Anger and denial as predictors of cardiovascular reactivity in women

The relationship between behavioral and physiological reactivity and cardiovascular disease has been extensively researched in men, indicating that the expression of anger may be a contributory factor in the development of coronary heart disease. Few studies, however, have focused on women. Among these, women generally have been found to be less reactive to laboratory tasks than men. In the present study, 45 women aged 19–21 years were selected to represent three groups—(1) low anger/low denial, (2) high anger/low denial, and (3) low anger/high denial—based on their scores on the State-Trait Anger Expression Inventory and the Marlowe-Crowne Social Desirability Scale. Subjects received three conditions: (1) no feedback, (2) error feedback without observer present, and (3) error feedback with observer present. As hypothesized, women who reported a high level of denial and low anger exhibited elevated stress-related reactivity. The results are suggestive of a subgroup of highly reactive women not previously identified within the literature. The hypothesis that all groups would display greater reactivity in a condition providing error feedback with observation was not supported.This study was supported by a research grant to Carol S. Emerson from the Women's Research Institute of Virginia.     

甲亢合并急性冠脉综合征的临床及冠脉特点研究

探讨甲亢合并急性冠脉综合征（ACS）患者的临床及冠状动脉病变特点.选取2010年1月至2013年6月于我院住院诊断的甲亢合并ACS患者（甲亢组）64例及甲状腺功能正常的ACS患者（对照组）56例,分析其临床及冠脉病变特点.甲亢组静息性心绞痛、高血压、糖尿病的发生率,纤维蛋白原（FIB）、氨基末端B型利钠肽前体（NT-proBNP）水平、零病变及冠状动脉痉挛比例明显高于对照组（P＜0.05）,低密度脂蛋白胆固醇（LDL-C）、总胆固醇（TC）水平明显低于对照组（P＜0.05）.甲亢合并ACS患者常发生静息性心绞痛,冠心病危险因素与甲状腺功能正常患者有所不同,零病变及冠脉痉挛比例高,冠状动脉痉挛可能是其发生急性心肌缺血的重要机制.