白细胞介素-6和胎盘生长因子对子痫前期影响的研究

为探讨影响子痫前期患者发病的因素,对照性检测了子痫前期患者羊水中白细胞介素-6和胎盘中胎盘生长因子的变化。结果显示：子痫前期患者白细胞介素-6和胎盘生长因子均明显下降,且二者下降水平呈高度正相关。故联合检测白细胞介素-6和胎盘生长因子将对评估子痫前期的病情及指导临床决策具有重要意义。     

Socioeconomic Differences in Psychosocial Factors Contributing to Coronary Heart Disease: A Review

Psychosocial factors have been shown to play an important role in the aetiology of coronary heart disease (CHD). A strong association between CHD and socioeconomic status (lower-level education, poor financial situation) has also been well established. Socioeconomic differences may thus also have an effect on psychosocial risk factors associated with CHD, and socioeconomic disadvantage may negatively affect the later prognosis and quality of life of cardiac patients. The aim of this study was to review the available evidence on socioeconomic differences in psychosocial factors which specifically contribute to CHD. A computer-aided search of the Medline and PsycINFO databases resulted in 301 articles in English published between 1994 and 2007. A comprehensive screening process identified 12 empirical studies which described the socioeconomic differences in CHD risk factors. A review of these studies showed that socioeconomic status (educational grade, occupation or income) was adversely associated with psychosocial factors linked to CHD. This association was evident in the case of hostility and depression. Available studies also showed a similar trend with respect to social support, perception of health and lack of optimism. Less consistent were the results related to anger and perceived stress levels. Socioeconomic disadvantage seems to be an important element influencing the psychosocial factors related to CHD, thus, a more comprehensive clarification of associations between these factors might be useful. More studies are needed, focused not only on well-known risk factors such as depression and hostility, but also on some lesser known psychosocial factors such as Type D and vital exhaustion and their role in CHD.     

Evolutionary perspective on indirect victimization in adolescence: the role of attractiveness, dating and sexual behavior

We studied indirect victimization from an evolutionary perspective by examining links between this type of victimization and several indicators of attractiveness (past sexual behavior, dating frequency and physical appearance). Two thousand three hundred and nineteen (56% female) students (ages 13-18) from a region of southern Ontario, Canada, completed self-report measures of indirect victimization, physical appearance, dating frequency, recent sexual behavior (number of partners in previous month) and past sexual behavior (number of lifetime partners minus number of partners in previous month) as well as indexes of depression, aggression and attachment security, which were used to control for psychosocial maladjustment. Consistent with an evolutionary framework, physical appearance interacted significantly with gender, wherein attractive females were at greater risk for indirect victimization, whereas for males physical attractiveness was a protective factor, reducing risk of victimization. Physical appearance also interacted with grade, being inversely related to indirect victimization for younger adolescents and having a nonsignificant association with victimization for older youth. Finally, recent sexual behavior was associated with increased risk of indirect victimization for older adolescents only, which we discussed with regard to peer perceptions of promiscuity and short-term mating strategies. These findings have important implications for the development of interventions designed to reduce peer victimization, in that victims of indirect aggression may represent a rather broad, heterogeneous group, including attractive individuals with no obvious signs of maladjustment.     

Mapping Gray’s BIS and BAS constructs onto Factor 1 and Factor 2 of Hare’s Psychopathy Checklist – Revised

Reinforcement sensitivity theory (RST; Gray, 1987; Gray & McNaughton, 2000) has proven to be a valuable tool for understanding psychopathy (e.g., Fowles, 1980, 1988; Newman & Malterer, 2009; Poythress et al., 2008). Recent research has linked two RST constructs, the Behavioral Inhibition System (BIS) and the Behavioral Activation System (BAS), to individuals with primary psychopathy and secondary psychopathy (Lykken, 1995; Newman, MacCoon, Vaughn, & Sadeh, 2005): Primary psychopaths manifest low BIS reactivity and secondary psychopaths manifest high BAS reactivity. In the present study, we examine the relationships between the BIS/BAS constructs and Factors 1 and 2 of the Psychopathy Checklist – Revised (PCL-R) in a sample of 472 incarcerated male offenders. Paralleling their relationships with primary and secondary psychopathy, the BIS/BAS constructs were differentially related to the two PCL-R factors. Specifically, the influence of the BIS was found to be more prominent than the influence of the BAS for Factor 1, and the influence of the BAS was more prominent than that of the BIS for Factor 2.     

Effect of multimodal takeover request issued through A-pillar LED light,earcon, speech message,and haptic seat in conditionally automated driving

The driver of a conditionally automated vehicle equivalent to level 3 of the SAE is obligated to accept a takeover request (TOR) issued by the vehicle. Considerable research has been conducted on the TOR, especially in terms of the effectiveness of multimodal methods. Therefore, in this study, the effectiveness of various multimodalities was compared and analyzed. Thirty-six volunteers were recruited to compare the effects of the multimodalities, and vehicle and physiological data were obtained using a driving simulator. Eight combinations of TOR warnings, including those implemented through LED lights on the A-pillar, earcon, speech message, or vibrations in the back support and seat pan, were analyzed to clarify the corresponding effects. When the LED lights were implemented on the A-pillar, the driver reaction was faster (p = 0.022) and steering deviation was larger (p = 0.024) than those in the case in which no LED lights were implemented. The speech message resulted in a larger steering deviation than that in the case of the earcon (p = 0.044). When vibrations were provided through the haptic seat, the reaction time (p < 0.001) was faster, and the steering deviation (p = 0.001) was larger in the presence of vibrations in the haptic seat than no vibration. An interaction effect was noted between the visual and auditory modalities; notably, the earcon resulted in a small steering deviation and skin conductance response amplitude (SCR amplitude) when implemented with LED lights on the A-pillar, whereas the speech message led to a small steering deviation and SCR amplitude without the LED lights. In the design of a multimodal warning to be used to issue a TOR, the effects of each individual modality and corresponding interaction effects must be considered. These effects must be evaluated through application to various takeover situations.     

Internet addiction,self-esteem and the validation of the Italian version of the Internet Related Experiences Questionnaire

IntroductionThe continued progression of the digital age raises the question of Internet and social media abuse among adolescents and of the need for more specific assessment instruments to measure the phenomenon.ObjectiveThe purpose of the current study was to explore the role of intrapersonal and interpersonal factors influencing Internet addiction, as well as to evaluate the psychometric properties of the Internet Related Experiences Questionnaire (IREQ-I) in relation to a sample of Italian adolescents.MethodTwo studies were designed. In study 1, a school-based sample of 838 Italian adolescents was recruited to test the psychometric properties of the IREQ-I by using a robust Confirmatory Factor Analysis (CFA). In study 2, a total of 438 Italian adolescents were recruited to investigate the concurrent validity of the instrument.ResultsWe found that intrapersonal rather than interpersonal factors were associated with Internet abuse. The final version of the IREQ-I showed a good level of fit and the bi-factorial solution was consistent with the previous findings.ConclusionThe results of this study suggest that the IREQ-I is a valuable bifactorial instrument for measuring Internet abuse, including both intrapersonal and interpersonal factors as theoretically relevant constructs.     

The effect of additional variables on factor indeterminacy in models with a single common factor

Determinate solutions for the indeterminate common factor ofp variables satisfying the single common factor model are not unique. Therefore an infinite sequence of additional variables that conform jointly with the originalp variables to the original single common factor model does not determine a unique solution for the indeterminate factor of thep variables (although the solution is unique for the factor of the infinite sequence). Other infinite sequences may be found to determine different solutions for the factor of the originalp variables. The paper discusses a number of theorems about the effects of additional variables on factor indeterminacy in a model with a single common factor and draws conclusions from them for factor theory in general.     

Dimensions of Early Childhood Behavior Problems: Stability and Predictors of Change from 18 to 30 Months

The prevalence, structure, stability, and predictors of change in early behavior problems were examined in a population-based sample of Norwegian children at 18 and 30 months of age (N = 750). A clear factor structure involving four dimensions emerged at both assessment times: Two factors were characterized by externalizing behaviors and were labeled Social Adjustment and Overactive-Inattentive; one factor tapped internalizing problems and was labeled Emotional Adjustment; and the fourth, related to general immaturity, was labeled Regulation. Specific patterns of child and family risk factors were associated with stability and change over the two time points for each factor. Children with stable problems had the most problematic characteristics on all significant predictors, followed by children with problems at one, but not both, time points. The data suggest that it is possible to identify risk factors for stable problems at 18 months, allowing some prediction of those children whose problems will persist over early childhood. Since specific risk factors emerged for specific types of behavior problems, the results may provide some much-needed guidance to early intervention efforts.     

Definitional and Research Issues in the Common Factors Approach to Psychotherapy Integration: Misconceptions, Clarifications, and Proposals

This paper focuses on two common misconceptions of common factors in therapy. The first misconception entails the confusion between common factors and therapeutic factors, and thus the inappropriate and misleading use of the term therapeutic common factors in various situations. The second misconception is the mixing of commonalities of different kinds and levels in proposed lists and studies of common factors. These areas are discussed and clarified, and recommendations designed to facilitate conceptual and methodological improvements relative to each misconception are offered. The selection of best levels and kinds of common factors to be studied are further explored (i.e., the study of client change events and antecedent therapist behaviors across different therapies), and specific proposals for their research are outlined.     

The Client Is the Most Important Common Factor: Clients' Self-Healing Capacities and Psychotherapy

I first briefly review the dodo bird verdict and suggest that we should be responding to it by looking for a new way to conceptualize how therapy works. Then I describe the dominant medical or treatment model of psychotherapy and how it puts the client in the position of a dependent variable who is operated on by supposedly potent therapeutic techniques. Next I argue that the data do not fit with this model. An alternative model is that the client is the most important common factor and that it is clients' self-healing capacities which make therapy work. I then argue that therapy has two phases—the involvement phase and the learning phase—and that the involvement phase is the most important. I next review the five learning opportunities provided by therapy. Finally, I argue that a relational model of therapy focused on consultation, collaboration, and dialogue is better than a treatment model.