Connaissances et contrôle exécutif : deux facteurs cognitifs de protection contre le vieillissement de la mémoire épisodique ?

In this study we refer to Craik and Bialystok's model distinguishing the “knowledge” (cultural learning experience that forms the basis for knowledge of the world) and the “executive control” (set of operations that control and regulate cognitive performance) as two main factors susceptible accounting for the age-related negative effects on the cognitive functioning, and for a possible age-related protective effect. Thus, the aim of the present study was to examine the possible protective effect of these two factors on the age-related decline in a cued-recall task. Four age groups of participants (20–39 years, 40–59 years, 60–74 years and 75–90 years) were administered with a word-stem cued-recall test to assess episodic memory, a “vocabulary” sub-test of the WAIS-R to assess knowledge and a reading span test to assess control. Results showed an age-related effect on the episodic memory, the control performance and the knowledge measure, indicating that performance decreases with age. A GLM analysis revealed a positive effect of the knowledge and the control factors on the cued-recall performance, and interaction between age and the knowledge factor resulting from a positive effect of the knowledge level only for the youngest group of participants (20–39 years). Furthermore, results revealed an interaction between age and the control factor, indicating a positive effect of the control level for the two oldest groups of participants (60–74 years and 75–90 years). These results suggest that, contrary to the knowledge, the control factor could be an effective protection against the age-related negative effects on the episodic memory.     

主观幸福感研究综述

文章介绍了主观幸福感的涵义、内容和特点,总结了主观幸福感的研究理论,分析了影响主观幸福感的多种因素,并探讨了今后研究的方向和新的课题,旨在为今后的研究提供新的视角。     

Distinguishing Caregiver Strain from Psychological Distress: Modeling the Relationships Among Child, Family, and Caregiver Variables

Although both have been used in studies of the impact of mental illness on the family, the constructs of caregiver strain (often referred to as burden of care) and psychological distress have not been clearly distinguished. The vagueness surrounding these constructs, and the lack of a cohesive conceptual framework for understanding how they relate, leads to contradictory interpretations of results. This compromises the building of the knowledge base needed to develop and evaluate interventions to support families as they struggle to meet the needs of their children with emotional and behavioral challenges. We utilized the ABCX Model as a framework for understanding caregiver strain and its relationship to psychological distress. Structural equations modeling was used to test the hypothesized relationship between caregiver strain and psychological distress, as well as the role of key child and family variables. These included child symptoms, stressful life events, social support, family functioning, and material resources. Our findings indicated that caregiver strain and psychological distress, although related, have distinct correlates and different implications in the family context.     

A Mixed-Methodological Evaluation of a Subjective Well-Being Intervention Program With Elementary-Age Students

An embedded mixed-methods design was implemented with 34 elementary-age students (mean age = 10.15 years, SD = 0.65) to evaluate salient experiences and improvements in protective factors and life satisfaction associated with a subjective well-being intervention program (SWIP). Analyses resulted in a model of participant experiences in which thematic experiences with SWIP participation (improved emotional expression, enhanced self-discovery, and increased empathy) promoted the emergence of protective factors (self-concept and self-confidence) that contributed to life satisfaction.     

Calibrated Bayes Factors Should Not Be Used: A Reply to Hoijtink,van Kooten,and Hulsker

Hoijtink, Kooten, and Hulsker (2016 Hoijtink, H., van Kooten, P., &; Hulsker, K. (2016). Why Bayesian psychologists should change the way they use the Bayes factor. Multivariate Behavioral Research, 51, 1--9. doi: 10.1080/00273171.2014.969364.[Taylor &; Francis Online], [Web of Science ®] , [Google Scholar]) present a method for choosing the prior distribution for an analysis with Bayes factor that is based on controlling error rates, which they advocate as an alternative to our more subjective methods (Morey &; Rouder, 2014 Morey, R.D., &; Rouder, J.N. (2014). Bayesfactor: Computation of Bayes factors for common designs. R package version 0.9.9. Retrieved from http://CRAN.R-project.org/package=BayesFactor [Google Scholar]; Rouder, Speckman, Sun, Morey, &; Iverson, 2009 Rouder, J.N., Speckman, P.L., Sun, D., Morey, R.D., &; Iverson, G. (2009). Bayesian t-tests for accepting and rejecting the null hypothesis. Psychonomic Bulletin and Review, 16, 225–237. doi: 10.3758/PBR.16.2.225[Crossref], [PubMed], [Web of Science ®] , [Google Scholar]; Wagenmakers, Wetzels, Borsboom, &; van der Maas, 2011 Wagenmakers, E.-J., Wetzels, R., Borsboom, D., &; van der Maas, H. (2011). Why psychologists must change the way they analyze their data: The case of psi. A comment on Bem (2011). Journal of Personality and Social Psychology, 100, 426–432. doi: 10.1037/a0022790[Crossref], [PubMed], [Web of Science ®] , [Google Scholar]). We show that the method they advocate amounts to a simple significance test, and that the resulting Bayes factors are not interpretable. Additionally, their method fails in common circumstances, and has the potential to yield arbitrarily high Type II error rates. After critiquing their method, we outline the position on subjectivity that underlies our advocacy of Bayes factors.     

Treatment of Patients with Advanced Hepatocellular Carcinoma using Stem Cell Differentiation Stage Factors

Hepatocellular carcinoma (HCC) represents the third leading cause of cancer-related death. Because HCC is multicentric with time, excluding the few transplanted patients, sooner or later it becomes untreatable with loco-regional therapies and, until some years ago, it was not responsive to systemic therapies. In 2005 a randomized trial indicated the efficacy of a product containing stem cell differentiation stage factors (SCDSF) taken from zebrafish embryos during the stage in which the totipotent stem cells are differentiating into the pluripotent adult stem cells. In such a trial the patients, with “intermediate” and “advanced” HCC according to Barcelona Clinic Liver Cancer/American Association for the Study of Liver Diseases (BCLC/AASLD) guidelines, presented benefit in terms of performance status and objective tumoral response, with some cases (2.4%) of complete response, that is, sustained disappearance of the neoplastic areas or blood supply therein, accompanied by normalization of alpha-fetoprotein (AFP) levels (complete response [CR]). A second study reporting the experience of a tertiary referral center on patients with “advanced” stage confirmed the possibility to obtain CR. Out of 38 patients, 5 presented a sustained CR (13.1%). Improvement on PS was obtained in 17 patients (34.6%). No side effects occurred.     

Who,where, when: the demographic and geographic distribution of bicycle crashes in West Yorkshire

Factors associated with cycle safety, including international differences in injury and mortality rates, protective equipment and bicycle training, have been subject to increasing academic interest. Environmental variables associated with cycle safety have also been scrutinised, but few studies have focussed on geographical factors at the local level. This paper addresses this research gap by analysing a geo-referenced dataset of road traffic incidents, taken from the UK’s STATS19 dataset (2005–2012). We investigate incidents involving cyclists within West Yorkshire. This is an interesting case study area as it has an historically low cycling rate but very ambitions cycling plans following investment from the Department of Transport. West Yorkshire is found to be an unusually risky area for cyclists, with an estimated 53 deaths and 1372 serious injuries per billion kilometres cycled, based on census commuting statistics. This is roughly double the national average. This riskiness varies spatially and temporally, broadly in line with expectations from the previous literature. An unexpected result was that cycling seems to be disproportionately risky for young people in West Yorkshire compared with young people nationally. The case study raises the issue of potential negative health impacts of promoting cycling amongst vulnerable groups in dangerous areas. We conclude by highlighting opportunities for increasing cycling uptake via measures designed primarily to improve safety. The analysis underlying this research is reproducible, based on code stored at github.com/Robinlovelace/bikeR.     

神经性厌食症的生物-心理-社会模型

厌食症作为一种精神和躯体疾病严重危害个体健康。已有众多研究者从生物-心理-社会整体医学模型角度对厌食症进行了研究。厌食行为受到遗传基因易感性、中枢神经递质活性改变、人格特质、肥胖恐惧感、应激因素、"瘦"文化背景、家庭关系紊乱等的影响。未来应着力探讨神经内分泌与厌食症的因果关系并加强厌食症的预防、干预及治疗。