Cross‐Species Chimeras: Exploring a Possible Christian Perspective

Various entities that combine material from humans and other animals at either the cellular or subcellular level have attracted growing public interest. I explore the controversy by considering both the scientific rationale behind creating various entities that have prompted the greatest public concern and possible ethical implications. I note a number of potentially relevant biblical passages and reflect on the imago Dei and considerations of telos in order to prompt wider discussion regarding how Christians might respond to such emerging bioethical issues.     

Deriving ultrametric tree structures from proximity data confounded by differential stimulus familiarity

This paper presents a new procedure called TREEFAM for estimating ultrametric tree structures from proximity data confounded by differential stimulus familiarity. The objective of the proposed TREEFAM procedure is to quantitatively filter out the effects of stimulus unfamiliarity in the estimation of an ultrametric tree. A conditional, alternating maximum likelihood procedure is formulated to simultaneously estimate an ultrametric tree, under the unobserved condition of complete stimulus familiarity, and subject-specific parameters capturing the adjustments due to differential unfamiliarity. We demonstrate the performance of the TREEFAM procedure under a variety of alternative conditions via a modest Monte Carlo experimental study. An empirical application provides evidence that the TREEFAM outperforms traditional models that ignore the effects of unfamiliarity in terms of superior tree recovery and overall goodness-of-fit.     

Behavior analysis in consumer affairs: Retail and consumer response to publicizing food price information

A popular program among consumer action groups involves publicizing comparative food price information (CFPI) gathered from retail stores. Its significance is based on the assumption that publishing CFPI maximizes retail competition (i.e., moderates price levels or price increases) and occasions more frugal store selections among consumers. We tested these assumptions during a 2-year analysis. Specifically, we monitored the prices of two distinct market baskets in the supermarkets of two midwestern cities (target and contrast cities). Following a lengthy baseline, we published the prices of only one of the market baskets at stores in the target city in the local newspaper on five different occasions. The results suggested that reductions in price inflation occurred for both market baskets at the independently operated target stores. The corporate chain stores were not similarly affected. In addition, surveys indicated that many consumers used the CFPI as a basis for store selection. Finally, the analysis included a discussion of the politics, economics, and future of CFPI programs.     

A project to strengthen linkages between genetic centers and child welfare services

Genetic centers are reaching out to underserved populations. One of the most vulnerable underserved populations is children receiving child welfare services. Delivering genetic services to this group is particularly problematic because of multiple barriers. The first step in overcoming barriers is developing linkages between the genetic and adoption service systems with the goal of increasing referrals of child welfare clients to genetic services. This paper presents a model of fostering linkages that was developed under the auspices of the Mid-Atlantic Regional Human Genetics Network with support from the Maternal and Child Health Bureau, Genetic Services Branch. Although the project was regional and funded, the model can be applied at the local level.     

Decreasing fuel-oil consumption through feedback and social commendation

The energy crisis of the winter of 1973-74 led to severe shortages of fuel oil for home heating and a government request for voluntary conservation by the oil consumer. This experiment tested two methods of facilitating fuel-oil conservation. Home fuel-oil consumers were randomly assigned to one of three experimental groups: feedback of information on rate of oil use, feedback plus commendation for reduced consumption, or a no-treatment control. The consumption rate for the feedback plus commendation group was significantly lower than that of either the informational feedback group or the control group. The informational feedback group did not differ from the control group. The results suggest that feedback alone may not result in oil conservation, but that feedback combined with commendation can produce socially significant savings.     

Evaluating municipal policy: an analysis of a refuse packaging program

The effect of a municipal enforcement program to improve residents' packaging of refuse was analyzed in a multiple-baseline design across two areas of a city. The enforcement program involved instruction concerning refuse-packaging regulations, collection only of appropriately packaged refuse, and feedback notices to residents concerning the reasons for noncollection of their inadequately packaged refuse. Both the number of violations and the percentage of residences violating each day were markedly reduced during the enforcement program. Furthermore, sanitation workers considered that the packaging of refuse and the safety and efficiency of refuse collection had improved. This study served as a pilot evaluation of a policy change in the city sanitation department, and was functional in determining the direction of that policy.     

Protection of animal research subjects

The use of experimental animals, mostly rodents, in biomedical research and especially in oncology and immunology should be acknowledged with respect, recognizing the contribution of animal experimentation in the fascinating scientific progress in these disciplines of research. It is an obligation of the investigator to justify the scientific and ethical aspects of each study requiring the use of animals. The international guiding principles for using animals in biomedical research are well defined and have been distributed worldwide by the International Council for Laboratory Animal Science (ICLAS) since 1956, when this Organization was founded. In Poland the ICLAS philosophy and principles are highly respected and were implemented firstly by the members of the Commission on Biology of Experimental Animals appointed in 1962 by the Department of Medical Science of the Polish Academy of Science in Warsaw. Animal Protection Acts, first proclaimed in 1928 were gradually modified and improved. Actual legislation (enacted in 1997, 2003 and 2005) is consistent with EU Directives (86/609/EEC) and follows the internationally recommended principles that include ICLAS guidelines concerning animal welfare and care condition in biomedical research. The problem of “alternative methods” is briefly discussed. Dr. Donald Boisvert, CCAC — Canadian Council on Animal Care A lecture on the subject of this paper was presented at the 6th International Bioethics Conference entitled ‘The Responsible Conduct of Basic and Clinical Research’, held in Warsaw, Poland, 3–4 June 2005. The author is the National Representative of Polish Academy of Science to the International Council for Laboratory Animal Science (ICLAS) and a Member of the ICLAS Governing Board.     

Defining Location in the Mental Health System: A Case Study of a Consumer-Run Agency

In this ethnographic study of a mental health service agency staffed by “consumers,” or fellow “recipients” of services for serious mental illness, the concept of community narrative provides the framework for examining how such an agency preserves its consumer identity while providing services dictated by the established service system. Locating the agency's narrative in its “origins tale,” analysis revealed five principles comprising the agency's identity: a normalizing view of mental illness, a commitment to helping, a dual-valued understanding of the mental health system, and beliefs in recovery and in the significance of employment as a criterion for recovery. Predicted consequences of narrative functioning emerged in social climate and staff expressions of cohesion and commitment. The local meaning of these narrative themes reveals the agency's view of the consumer element in its work and its solution to the dilemma of being both inside and outside of the mental health system.     

Assessing Parental Satisfaction with Children’s Mental Health Services with the Youth Services Survey for Families

We assessed parent satisfaction with childrens mental health services with a new instrument: The Youth Services Survey for Families (YSSF). The Dillman method was used to administer the survey to a random sample of 1,500 parents of Medicaid youth from Kentuckys 14 community mental health centers (CMHCs). The response rate was 37% (n = 534 parents). A factor analysis of YSSF identified five parent-perceived factors: (a) Appropriateness, (b) Outcome, (c) Participation in Treatment, (d) Access, and (e) Cultural Sensitivity. About 70% of parents reported a high level of endorsement with the Appropriateness factor, but only 47% reported high levels of endorsement with the Outcome factor. Results were interpreted as providing support for the reliability of the YSSF in evaluating childrens mental health services in CMHCs.