空间导航的脑网络基础和调控机制

空间导航在生活中时刻发生,空间能力衰退是阿尔兹海默症的重要早期表现。早期关于空间导航神经机制的研究主要关注单个脑区的特异性功能,但这些脑区如何交互以整合不同模态的信息支持复杂导航行为尚不清楚。脑成像技术、脑网络建模方法和神经调控手段的发展,为在脑网络水平理解人类空间导航的认知神经机制提供了重要研究手段。本研究试图融合空间导航认知神经机制研究的最新进展,借助脑网络建模、大数据分析、微电流刺激等前沿研究手段,研究空间导航脑网络的关键拓扑属性特征(如模块化、核心节点等),探寻该功能特异性神经网络的重要影响因素和调控机制,并构建空间导航的脑网络理论模型。研究成果将有利于理解人类复杂导航行为的脑网络基础,为阿尔兹海默症等相关认知障碍脑疾病的筛查和诊断提供重要参考。     

Whole of community suicide prevention forums for Aboriginal Australians

It is well known that Aboriginal Australians are at increased risk of suicide. Contributors to suicide differ for Indigenous and non-Indigenous populations (Westerman, 2003; 2019). This study evaluated whole of community suicide prevention forums conducted across six locations. Attendees were youth (N = 136), service providers (N = 225), and community members (N = 158). The content of the forums was empirically based and, for service providers and community members, covered knowledge of suicide, and depression specific to Aboriginal people, skills relating to working with depressed and suicidal Aboriginal people, and intentions to help an Aboriginal person who is suicidal. Content for youth attendees focused on knowledge of suicide and depression, coping skills, intentions to help a friend, and beliefs about suicide. While the results demonstrated significant gains across most domains, there was a potentiating effect with some skills increases becoming more significant over each phase. This demonstrates that a whole of community approach to Indigenous suicide prevention is required, and that clinical and cultural skills require a longer-term approach for impact and sustainability.     

Do Cognitive Therapy Skills Neutralize Lifetime Stress to Improve Treatment Outcomes in Recurrent Depression?

Cognitive therapy (CT) is an efficacious treatment for major depressive disorder (MDD), but not all patients respond. Past research suggests that stressful life events (SLE; e.g., childhood maltreatment, emotional and physical abuse, relationship discord, physical illness) sometimes reduce the efficacy of depression treatment, whereas greater acquisition and use of CT skills may improve patient outcomes. In a sample of 276 outpatient participants with recurrent MDD, we tested the hypothesis that patients with more SLE benefit more from CT skills in attaining response and remaining free of relapse/recurrence. Patients with more pretreatment SLE did not develop weaker CT skills, on average, but were significantly less likely to respond to CT. However, SLE predicted non-response only for patients with relatively weak skills, and not for those with stronger CT skills. Similarly, among acute-phase responders, SLE increased risk for MDD relapse/recurrence among patients with weaker CT skills. Thus, the combination of more SLE and weaker CT skills forecasted negative outcomes. These novel findings are discussed in the context of improving CT for depression among patients with greater lifetime history of SLE and require replication before clinical application.     

Utilizing response times in cognitive diagnostic computerized adaptive testing under the higher-order deterministic input,noisy ‘and’ gate model

Methods of cognitive diagnostic computerized adaptive testing (CD-CAT) under higher-order cognitive diagnosis models have been developed to simultaneously provide estimates of the attribute mastery statuses of examinees for formative assessment and estimates of a latent continuous trait for overall summative evaluation. In a typical CD-CAT environment, examinees are often subject to a time limit, and the examinees’ response times (RTs) for specific test items can be routinely recorded by custom-made programs. Because examinees are individually administered tailored sets of test items from the item pool, they may experience different levels of speededness during testing and different levels of risk of running out of time. In this study, RTs were considered during the item-selection procedure to control the test speededness and the RTs were treated as useful information for improving latent trait estimation in CD-CAT under the higher-order deterministic input, noisy ‘and’ gate (DINA) model. A modified posterior-weighted Kullback–Leibler (PWKL) method that maximizes the item information per time unit and a shadow-test method that assembles a provisional test subject to a specified time constraint were developed. Two simulation studies were conducted to assess the effects of the proposed methods on the quality of CD-CAT for fixed- and variable-length exams. The results show that, compared with the traditional PWKL method, the proposed methods preserve a lower risk of running out of time while ensuring satisfactory attribute estimation and providing more accurate estimates of the latent trait and speed parameters. Finally, several suggestions for future research are proposed.     

A developmental study of the bat/ball problem of CRT: How to override the bias and its relation to executive functioning

In two experiments, we explored the nature of the bias observed in the bat/ball problem of the cognitive reflection test (Frederick, 2005, J. Econ. Perspect., 19, 25), how to override it, and its relation to executive functioning. Based on the original bat/ball problem, we designed two additional isomorphic items. In Experiment 1, for four age groups, including 7-, 11-, and 15-year-olds and adults, we determined that the bias is related to the System 1 intervention; the performance in this item was not a matter of mathematical ability and it could be facilitated by changing the order in which the problems were presented. In Experiment 2, we determined that for 15-year-olds, good and bad performances in the item were related to executive functioning, particularly response-distractor inhibition, updating information in working memory, and the regulation of attention; however, subtle differences were identified when the problem was performed in a facilitative context compared with a non-facilitative context. The results indicated that cognitive abilities are a necessary but non-sufficient condition to resolve the problem.     

The longitudinal association between social status insecurity and relational aggression: Moderation effects of social cognition about relational aggression

Previous research has shown that adolescents’ insecurity about their social status is related to their use of relational aggression. However, little is known about how adolescents’ social cognition may moderate this association. Employing a mixed-method approach and a short-term longitudinal design, this study addresses this issue by examining the moderation effects of attribution and outcome expectancies regarding relational aggression on the associations between social status insecurity and relational aggression among 476 Chinese adolescents (238 girls). The main results showed that self-serving attributions and instrumental outcome expectancies strengthened the positive and longitudinal association between social status insecurity and self-reported relational aggression. The findings of this study enrich our knowledge about the social cognitive processes pertinent to peer status and relational aggression among adolescents.     

Being proven wrong elicits learning in children – but only in those with higher executive function skills

This study investigated whether prompting children to generate predictions about an outcome facilitates activation of prior knowledge and improves belief revision. 51 children aged 9–12 were tested on two experimental tasks in which generating a prediction was compared to closely matched control conditions, as well as on a test of executive functions (EF). In Experiment 1, we showed that children exhibited a pupillary surprise response to events that they had predicted incorrectly, hypothesized to reflect the transient release of noradrenaline in response to cognitive conflict. However, children's surprise response was not associated with better belief revision, in contrast to a previous study involving adults. Experiment 2 revealed that, while generating predictions helped children activate their prior knowledge, only those with better inhibitory control skills learned from incorrectly predicted outcomes. Together, these results suggest that good inhibitory control skills are needed for learning through cognitive conflict. Thus, generating predictions benefits learning – but only among children with sufficient EF capacities to harness surprise for revising their beliefs.     

Individual differences in neonatal “imitation” fail to predict early social cognitive behaviour

The influential hypothesis that humans imitate from birth – and that this capacity is foundational to social cognition – is currently being challenged from several angles. Most prominently, the largest and most comprehensive longitudinal study of neonatal imitation to date failed to find evidence that neonates copied any of nine actions at any of four time points (Oostenbroek et al., [2016] Current Biology, 26, 1334–1338). The authors of an alternative and statistically liberal post‐hoc analysis of these same data (Meltzoff et al., [2017] Developmental Science, 21, e12609), however, concluded that the infants actually did imitate one of the nine actions: tongue protrusion. In line with the original intentions of this longitudinal study, we here report on whether individual differences in neonatal “imitation” predict later‐developing social cognitive behaviours. We measured a variety of social cognitive behaviours in a subset of the original sample of infants (N = 71) during the first 18 months: object‐directed imitation, joint attention, synchronous imitation and mirror self‐recognition. Results show that, even using the liberal operationalization, individual scores for neonatal “imitation” of tongue protrusion failed to predict any of the later‐developing social cognitive behaviours. The average Spearman correlation was close to zero, mean r_s = 0.027, 95% CI [?0.020, 0.075], with all Bonferroni adjusted p values > .999. These results run counter to Meltzoff et al.'s rebuttal, and to the existence of a “like me” mechanism in neonates that is foundational to human social cognition.     

体像障碍的认知机制及治疗

体像障碍是一种对想象的或轻微外表缺陷的先占观念, 这种先占观念给个体带来极大的痛苦。其负性的自我认知框架, 影响个体对信息的选择、组织及评估。因此结合心理实验范式和神经生理综合分析体像障碍的认知过程, 对深化体像障碍认知机制和优化其认知行为治疗具有重要意义。     

信任的认知神经网络模型

信任是指一方在基于对另一方行为期望的基础上愿意冒一定的风险, 以期在将来得到积极结果的心理过程。近年, 认知神经取向的研究对信任行为引起的特定脑区激活进行了考察, 却忽略了大规模脑网络在信任过程中的整体作用。在总结前人研究的基础上提出信任的认知神经网络模型, 并从认知神经网络视角对信任行为进行解释和整合。在模型中, 信任行为是动力系统、情感系统和认知系统相互作用的结果, 并分别与奖励网络、显著网络、中央执行网络和默认网络等神经网络激活有关。此外, 模型还强调信任行为的反馈机制, 以此构成完整的建构模型。模型阐明了心理系统与中枢神经网络之间的对应关系, 从认知神经角度解释了信任行为发生的心理机制和神经基础。