Shooting Genes,Distributing Credit: Narrating the Development of the Biolistic Gene Gun

Using oral histories with scientists, technology transfer managers and other collaborators who were involved with the development of the biolistic gene gun, I investigate how actors narrate their experiences of technology transfer. The individuals who worked on the gene gun draw on two different interpretive repertoires for describing the innovation process: a ‘localized’ repertoire that highlights defined moments and the conceptual contributions of a few individuals; and a ‘distributed’ repertoire that emphasizes longer time frames, the process of technical implementation and the importance of a network of collaborators. Each of these repertoires identifies a different assemblage of actors as deserving of credit and reward for the development of the gene gun. Examining how scientists employ these modes of describing the innovation process offers a way of thinking about how university inventors negotiate tensions around novel features of academic capitalism, such as personal profit arising from the commercialization of university technologies.     

Lost in Translation? The Need for ‘Upstream Engagement’ with Nanotechnology on Trial

Nowadays, the criticism of the so-called ‘deficit model’ and the need for ‘upstream engagement’ in science and technology are becoming part of the master narratives of public policies in many countries, especially concerning nanotechnology. This may be considered as a major success for STS scholars, whose research results have largely contributed to this change, especially those concerning the GMO controversies. Some STS scholars thus move from a position of distant and critical observers to the role of experts in social engineering or advisers of policy-makers. However, in their enthusiasm concerning the expected benefits of upstream engagement, institutions, TA practitioners and social scientists seem to ignore some important limitations as well as the implicit framing assumptions of the concept. Based on an experience made by a group of social scientists in the Grenoble area—one of the major ‘nanodistricts’ in Europe—our paper shows that the ‘upstream engagement’ concept is still embedded in a linear model of innovation and is not very useful to anyone pursuing the co-production of innovations. It is especially true when socio-technical networks are already aligned by powerful actors and a worldwide agenda as in the case of nanotechnology. In order to give an opportunity for public engagement to have a larger impact on decision-making, we propose an alternative approach, which combines Actor–Network Theory (ANT), as an analytical tool, with the reflexive and ongoing implementation of public participation. Public engagement is probably one of the critical loci where STS scholars must reflect on the articulation between the knowledge they produce and public policies in action.     

布氏杆菌病诊治体会

加强对布氏杆菌病流行病学资料、临床特点、诊断、治疗、预后及本病误诊误治的前因后果等方面的认识,回顾性分析潍坊医学院附属医院近两年收治的28例布氏杆菌病病例,并总结布氏杆菌病在诊断、治疗等方面的特点.经查阅国内外资料分析所得,近20余年,布氏杆菌病发病率呈上升趋势,传播途径复杂,临床表现无特异性,易误诊误治;利福平、四环素及喹诺酮药物疗效肯定,治愈率高.临床医师须加强对本病的全面认识,提高诊断率并提供规范治疗、减轻患者心理及精神负担.     

临床护士心理弹性现状及其影响因素的研究

了解临床护士心理弹性现状,分析影响护士心理弹性的因素,为管理者掌握临床护士心理健康状况,提高心理弹性水平提供参考依据。采用中文版心理弹性量表（CD—RISC）,对535名临床护士进行调查。结果显示,临床护士心理弹性总分为（56．78±18．43）分;其心理弹性在不同人口统计学方面差异均有统计学意义（P〈0．05）;多元逐步回归分析显示心理弹性的主要影响因素是：工作年限和是否为独生子女。临床护士心理弹性处于中等水平,医院管理者应重视培养个体心理弹性素质,有针对性地开展弹性拓展训练,提高护理质量。     

医学生临床实习应掌握的几种哲学思维方式

为适应全球卫生事业的迅猛发展,面对医学教育落后于医学发展的现状,转化医学教育迫在眉睫。在第三代“以系统为基础”的教育改革中,培养医学生的哲学思维无疑是其重要环节之一。思维方式必须在医学生步入临床时就要开始正确培养,一旦开始阶段就养成不正确的思维方式、不但会导致医疗过程中的失误,而且再想改变将会有很大难度。本文通过对医学哲学重要性的探讨,剖析医学生哲学思维的不足,阐述了医学生,临床实习过程中应掌握的几种哲学思维方式。旨在提高医学生的哲学理念,促进以岗位胜任能力为导向的医学教育转型发展。     

我国转化医学发展现状的思考

转化医学在当今世界发展迅速,虽然在我国起步较晚,但取得了巨大的成就,建立了许多转化医学研究机构,积极开展合作交流,但不可避免地存在一些问题,诸如创新能力不足、顶层设计不够和人才缺乏等,为此提出相应对策和未来发展的前景,同时指出转化医学在我国不仅是学术问题,而且是社会问题.     

最大信息量法在CCSPC评分中应用的效度证据

采用基于最大信息量法的多维项目反应理论模型估计计算机模拟心理咨询病例系统（CCSPC）的合成分数及四个模块分数,并收集效标效度证据、成长变化效度证据和内容效度证据,结果表明：五个指标与心理咨询师考试三级技能成绩的相关均达到显著,且高于其与三级理论成绩的相关;所有指标得分均随着心理学学历升高而升高;多数指标分数随心理学本科年级提高而提高;获得心理咨询师资格认证的被试在CCSPC上有更高的得分.     

Exercising Research Skills: An Information Literacy Boot Camp for Religious Studies Graduate Assistants

Instructional librarians at the University of Dayton collaborated with a religious studies graduate program to offer a three-day information literacy workshop, or “boot camp,” to the program's graduate research assistants. The graduate program had found that the assistants' research skills did not meet the expectations of their faculty mentors, and the workshop sought to address these deficiencies. With input from the religious studies faculty, the workshop focused on catalog and database searching, Boolean logic, primary sources, and the Chicago citation style. The librarians incorporated active learning exercises into each workshop session. Assessment of the workshop suggested that the assistants gained confidence in these information literacy skills. Feedback from faculty also indicated that the assistants' research skills had improved.     

New Horizons: A Center for Research into Information and Religion

This article introduces the creation of a new research center focused on the study of information and religion. The Center, located at Kent State University, provides a new opportunity for scholars in the field of library and information science to collaborate with researchers in other disciplines in the exploration of many potential intersections of information and religion. The Center founders have already begun to present and publish in this area. Planned symposia and an annual conference add to the exposure of interested parties to ongoing studies in this field.     

Shaping Medical Students' Attitudes Toward Ethically Important Aspects of Clinical Research: Results of a Randomized,Controlled Educational Intervention

The effects of research ethics training on medical students' attitudes about clinical research are examined. A preliminary randomized controlled trial evaluated 2 didactic approaches to ethics training compared to a no-intervention control. The participant-oriented intervention emphasized subjective experiences of research participants (empathy focused). The criteria-oriented intervention emphasized specific ethical criteria for analyzing protocols (analytic focused). Compared to controls, those in the participant-oriented intervention group exhibited greater attunement to research participants' attitudes related to altruism, trust, quality of relationships with researchers, desire for information, hopes about participation and possible therapeutic misconception, importance of consent forms, and deciding quickly about participation. The participant-oriented group also agreed more strongly that seriously ill people are capable of making their own research participation decisions. The criteria-oriented intervention did not affect learners' attitudes about clinical research, ethical duties of investigators, or research participants' decision making. An empathy-focused approach affected medical students' attunement to research volunteer perspectives, preferences, and attributes, but an analytically oriented approach had no influence. These findings underscore the need to further examine the differential effects of empathy-versus analytic-focused approaches to the teaching of ethics.