基于“相关线索-自动化用药行为”联结的成瘾记忆消退

成瘾记忆消退致力于消除成瘾者相关线索与药物奖赏效应的联结,以达到消除心理渴求、戒断成瘾行为的目的,但其效果还十分有限。最近,大量的动物和人类实验研究发现:在相关线索下,成瘾者的激活脑区不仅包括中脑边缘皮层-背内侧纹状体,还延伸到感觉运动脑区-背外侧纹状体。这意味着成瘾记忆中存在相关线索与自动化(习惯性)用药行为的联结。所以,与成瘾相关的记忆可能包含两种不同的成分:一是与药物奖赏效应相关的情绪记忆,另一种是与用药动作、技能有关的动作记忆(程序记忆)。由于在成瘾阶段,药物奖赏效应对药物使用和复发的作用已经相对减少,因此,针对成瘾记忆的消退训练,以相关线索与自动化用药行为的联结为标靶,可能可以取得更好的效果,值得做进一步的深入探索。     

网络游戏成瘾与海洛因成瘾存在相同的神经机制吗?——基于MRI的证据

网游成瘾与海洛因成瘾具有许多相似的临床表现,但其神经机制是否相同还不得而知。综合近5年来的MRI研究发现,两类成瘾存在部分相同区域的脑结构和功能损害,且在成瘾线索诱发下二者的4个成瘾相关环路(认知控制环路、奖赏环路、动机环路和记忆-学习环路)均出现了广泛而增强的脑区激活反应。但海洛因成瘾的脑损害区域偏向更高级的认知控制环路和奖赏环路,损害范围也更广(4个环路的功能连通性均降低),而网游成瘾的脑损害主要发生在相对低级的记忆-学习环路和动机环路,损害范围也较窄(功能连通性降低只发生在认知控制和记忆-学习环路之间)。这些结果说明,两类成瘾行为的神经机制既有相同点,又有差异性。     

Predictors of Unintentionally Severe Harm During Nonsuicidal Self‐Injury

This study aimed to identify predictors of unintentionally severe injury during nonsuicidal self‐injury (NSSI). The authors examined 3 potential predictors in a sample of 102 college students: addictive qualities of NSSI, impulsivity, and dissociation. Both impulsivity and addictive qualities of NSSI were associated with unintentionally severe injury during NSSI. In a logistic regression, only addictive qualities of NSSI emerged as a significant predictor of unintentionally severe injury during NSSI. Implications for counseling and research are discussed.     

冲动性人格、亲子沟通对青少年网络成瘾的交互作用分析

本研究通过对1610名初一至高三学生的问卷调查,考察了冲动性人格、亲子沟通对青少年网络成瘾的交互影响。经过方差分析、相关分析和回归分析的结果表明：（1）与非网瘾青少年相比,网瘾倾向青少年的行动冲动性和无计划冲动性显著更高,与父亲和母亲的沟通都更差;（2）行动冲动性、认知冲动性和无计划冲动性均与青少年网络成瘾成显著正相关,而父子沟通和母子沟通均与青少年网络成瘾成显著负相关;（3）行动冲动性和无计划冲动性可正向预测青少年网络成瘾,但认知冲动性的预测作用不显著;母子沟通可负向预测青少年网络成瘾,但父子沟通的预测作用不显著;（4）行动冲动性和母子沟通对青少年网络成瘾存在交互影响,具体而言,对于低行动冲动性青少年而言,母子沟通对其网络成瘾具有显著的负向预测效应;但对于高行动冲动性青少年而言,母子沟通对其网络成瘾具有正向但不显著的预测作用。     

Drug addiction. Is it a disease or is it based on choice? A review of Gene Heyman's Addiction: A disorder of choice.

In Addiction: A disorder of choice, Gene Heyman surveys a broad array of evidence—historical, anthropological, survey, clinical, and laboratory‐based to build an argument about the role of basic choice processes in the phenomena that comprise drug addiction. He makes a compelling, multifaceted argument that conceptualizing drug addiction as a chronic disease (like schizophrenia or diabetes) is both misleading and erroneous. In developing his argument, he points out that the best survey data available indicate that most drug addicts quit their addiction, a fact inconsistent with a chronic‐disease model. He illustrates how basic, normal choice processes can lead to addiction, arguing that people do not choose to be addicts, but that normal choice dynamics can lead them to that condition. He points to a variety of factors that keep most from becoming addicted, with a focus on the role of choice governed by choice‐by‐choice contingencies versus choice governed by the outcome of sequences of choices, a difference in an under‐described activity called framing. His view is consistent with the most effective treatments currently available, and provides a basis for continued basic research on choice as well as research on treatment and prevention.     

Simulating demand for cigarettes among pregnant women: A Low‐Risk method for studying vulnerable populations

A substantive obstacle to experimentally studying cigarette smoking and use of other tobacco products in pregnant women is the risk of adverse effects on mother and fetus from experimenter administration of the product of interest. The purpose of this study is to investigate bypassing that obstacle by using behavioral economic simulation tasks. In the present study we used the Cigarette Purchase Task (CPT) to simulate changes in demand for hypothetical cigarettes as a function of varying cigarette prices. Participants were 95 pregnant women who completed the CPT prior to participation in a smoking‐cessation trial. Aggregate and individual participant demand varied as an orderly function of price and those changes were well fitted by an exponential equation. Demand also varied in correspondence to two well‐validated predictors of individual differences in smoking cessation among pregnant women (cigarettes smoked per day, pre‐pregnancy quit attempts). Moreover, CPT indices were more effective than these two conventional variables in predicting individual differences in whether women made a quit attempt during the current pregnancy. Overall, these results represent a promising step in demonstrating the validity and utility of the CPT for experimentally examining demand for cigarettes, and potentially other tobacco and nicotine delivery products, among pregnant women.     

基于技术接受模型的青少年网络游戏成瘾机制研究

本研究以技术接受模型(TAM)为理论框架, 通过对380名中学生的问卷调查考察了青少年网络游戏成瘾的影响因素及其机制。结果发现:(1)有用感、易用感、品质感知、游戏体验和态度与网络游戏成瘾显著正相关;(2)品质感知和游戏体验通过态度的部分中介作用对网络游戏成瘾产生间接影响, 同时对网络游戏成瘾有直接效应;有用感和易用感通过态度的完全中介作用对网络游戏成瘾产生间接影响, 对网络游戏成瘾没有直接效应。本研究结果表明, 品质感知、有用感、易用感和游戏体验对青少年网络游戏成瘾具有重要影响, 态度是其中的重要中介变量。     

网络成瘾倾向者在视觉工作记忆引导下的注意捕获

采用工作记忆任务和视觉搜索任务相结合的双任务范式, 探讨网络成瘾倾向者在视觉工作记忆引导下的注意捕获。实验1考察了单一分心刺激视场中分心刺激的性质对网络成瘾倾向者选择性注意的影响, 实验2通过控制匹配试验出现的概率来诱发不同的抑制动机, 探讨多分心刺激视场中两种抑制动机下网络成瘾倾向者的注意表现。结果发现：(1)无论在单一分心刺激还是多分心刺激视场中, 网络成瘾倾向被试的目标搜索反应时均显著短于正常组被试, 且两组的搜索正确率没有差异。(2)在单一分心刺激视场中, 无论是与工作记忆项目匹配还是不匹配的分心刺激都会捕获正常组被试的注意, 但不会捕获网络成瘾倾向被试的注意。(3)在多分心刺激视场中, 当抑制动机水平较低时, 两组被试均对匹配分心物产生注意捕获效应, 且网络成瘾倾向被试受工作记忆引导的注意捕获效应小于正常组被试; 当抑制动机较高时, 两组被试均对匹配分心物产生注意抑制效应, 且没有差异。研究结果表明, 面对非网络相关视觉刺激时, 网络成瘾倾向者受工作记忆引导的注意捕获效应小于正常组, 并表现出了知觉加工上的优势。     

Resisting Gendered Smoking Pressures: Critical Consciousness as a Correlate of Women's Smoking Status

Gender is one of the social structures, along with social class and ethnicity, that shapes women's smoking behaviors. We examined how different responses to gender pressures (internalization and resistance) relate to smoking. We analyzed data from a national random digit dial survey of 945 women and found that never smokers scored high on resistance to gender pressure (indicated by high scores on feminist consciousness) and on education and Body Mass Index; current smokers had the reverse pattern. Ex-smokers scored high on one measure of resistance (advertising skepticism) and on two measures of internalization (embodied femininity and weight concern); they were also likely to have high household income and to be European American. Results are discussed in terms of their implications for smoking cessation programs and antismoking campaigns.     

Matching therapeutic interventions to drug and alcohol abusers’ stage of motivation: The clients’ perspective

The present study aims to explore the issue of matching the appropriate therapeutic intervention according to the stage of readiness for change in addictive clients, following the model proposed by Prochaska and DiClemente in the 1980s. The study focuses solely on the perspectives of people with drug and alcohol problems, in contrast to previous ones which have been concerned with the researchers’ understandings and postulations of the issue under exploration. One of the most important findings of this study is that participants in the “early” stages of their readiness to change their addictive behaviour, irrespective of their gender or whether they had seen a therapist significantly prefer non-action-oriented therapeutic interventions than action-oriented interventions. Similarly, participants in the “later” stages, showed a significant preference to action-oriented than non-action interventions, irrespective of their gender or previous experience of counselling. It is suggested then that careful assessment of the stage of motivation and individual-tailored intervention should be an essential element of any treatment program for drug and alcohol addicted clients.