Developmental stuttering and the role of the supplementary motor cortex

Developmental stuttering is a frequent neurodevelopmental disorder with a complex neurobiological basis. Robust neural markers of stuttering include imbalanced activity of speech and motor related brain regions, and their impaired structural connectivity. The dynamic interaction of cortical regions is regulated by the cortico-basal ganglia-thalamo-cortical system with the supplementary motor area constituting a crucial cortical site. The SMA integrates information from different neural circuits, and manages information about motor programs such as self-initiated movements, motor sequences, and motor learning. Abnormal functioning of SMA is increasingly reported in stuttering, and has been recently indicated as an additional “neural marker” of DS: anatomical and functional data have documented abnormal structure and activity of the SMA, especially in motor and speech networks. Its connectivity is often impaired, especially when considering networks of the left hemisphere. Compatibly, recent data suggest that, in DS, SMA is part of a poorly synchronized neural network, thus resulting in a likely substrate for the appearance of DS symptoms. However, as evident when considering neural models of stuttering, the role of SMA has not been fully clarified. Herein, the available evidence is reviewed, which highlights the role of the SMA in DS as a neural “hub”, receiving and conveying altered information, thus “gating” the release of correct or abnormal motor plans.     

小学生近似数量系统敏锐度的发展趋势及其与数学能力的关系：抑制控制的中介作用

采用测量法和问卷法考察了172名小学生近似数量系统敏锐度的发展,以及抑制控制在近似数量系统敏锐度与数学能力关系中的中介效应。结果表明：(1)随着年龄增长,小学生的近似数量系统敏锐度逐渐提高;(2)近似数量系统敏锐度(负相关序列中的韦伯系数)和抑制控制均能显著正向预测小学生的数学能力;(3)抑制控制在小学生近似数量系统敏锐度(负相关序列中的韦伯系数)与数学能力的关系中起部分中介作用。     

多巴胺系统基因对注意网络的调控作用

多巴胺是脑内重要的神经递质之一,与注意活动紧密相关。本文选取作用于突触前膜、间隙和后膜的多巴胺系统基因——多巴胺转运蛋白基因、儿茶酚氧化甲基转移酶基因和多巴胺受体基因,整合影像遗传学研究,探讨多巴胺基因对注意网络的调控。元分析发现背侧和腹侧注意网络的主要脑区均有较大的基因调控效应,且腹侧网络的效应值显著大于背侧网络,表明多巴胺系统基因在全脑范围内调控注意网络,且对腹侧网络的调控作用更强于背侧网络。     

论行政调解的法制建构

行政调解是我国调解制度的重要构成部分,是"大调解"纠纷解决机制的重要环节,对解决社会纠纷、化解社会矛盾具有特殊重要的地位和功能。但是我国行政调解法律制度至今尚未建立起来。本文认为,我国调解法律制度建设的目标是在《人民调解法》的基础上,制定统一的《调解法》,建构较为完备的调解法律制度。当前的重点是建立和完善行政调解制度,建议在《调解法》制定之前由国务院制定《行政调解条例》,建立较为完整的行政调解法律制度,国务院行政法规制定以前,各省、自治区、直辖市人大常委会可以先行制定行政调解的地方性法规,将行政调解纳入法治轨道。进而,本文围绕构建我国行政调解法律制度,对我国行政调解的概念界定、行政调解主体、行政调解的范围、行政调解的基本原则、行政调解的程序和行政调解协议的法律效力等问题进行了较为系统的探讨。     

“垂衣裳”与儒家礼制

“垂衣裳”早见于《易传·系辞下》,最初用以形容包括尧、舜在内的圣王形象.“衣裳”的色彩、图案、样式被认为源于圣人观象,体现“乾坤尊卑”之理.儒家将“衣裳”视为标示等级和管理社会的工具,认为“衣裳”根源于‘礼”,服务于“礼”,损益于“礼”,具有礼乐教化的功能.“垂衣裳而治”就是圣王以服制垂示天下,而天下大治.从“垂衣裳”可以窥探儒家“无为而治”之究竟.     

The effects of motion on in-vehicle touch screen system operation: A battle management system case study

The use of in-vehicle touch screen devices is currently common in both military and civilian vehicles; despite this, the effects of motion on touch screen device operation within vehicles remains largely unexplored. This article describes a study that examined, using driving simulation, the influences of motion on performance, workload and usability when using a touch screen in-vehicle battle management system. Acting in the role of battle management system operator, 20 participants undertook four simulated drives, two under high motion (representative of an unsealed road) and two under normal motion (representative of a sealed road), whilst performing various battle management tasks. In the high motion condition, lower accuracy and longer task completion times were found, along with greater levels of subjective and physiological workload and lower levels of perceived device usability, when compared to the normal motion condition. The findings indicate that, compared to normal motion, the high motion condition impaired key aspects of battle management system operation. In closing, the importance of considering motion and its effects during touch screen system design is discussed.     

Les apprenti-e-s face aux contraintes en formation professionnelle en alternance : entre souffrance et plaisir

This paper focuses on the Swiss dual system of vocational education and training (VET), on the basis of the results of a study on VET dropouts. The adopted theoretical framework and method of analysis is the psychodynamic of work, which makes it possible to stress the specific constraints of a system that is closely related to the world of work. The various forms of suffering evoked by apprentices, as well as the strategies implemented to cope with it, are highlighted. The analyses also stress the pleasure young people can experience in VET. Between pleasure and suffering, these elements make it possible to consider both the assets and the shortcomings of this education system.     

Structural properties of personal meaning systems: A new approach to measuring meaning of life

This article introduces a new qualitative–quantitative approach to assess meaning of life. The participants described their sources of meaning and how they were interconnected. Four quantitative measures for (1) the accessibility of meaning-related knowledge, the degree of (2) differentiation and (3) elaboration of personal meaning systems, and (4) their coherence were calculated. The sample consisted of 59 theology and science students. The study tested (a) whether the structural properties of personal meaning systems predicted health and well-being, and (b) reflected different degrees of expertise in constructing meaning. Differentiation, elaboration, and coherence measures correlated with health and well-being and predicted life satisfaction. Theology students presented more differentiated, elaborated, and coherent personal meaning systems than science students. Both results indicate that assessing structural properties of personal meaning systems can be a promising new approach to measure meaning of life.     

EPS Mid-Career Award 2014

In visual search, observers try to find known target objects among distractors in visual scenes where the location of the targets is uncertain. This review article discusses the attentional processes that are active during search and their neural basis. Four successive phases of visual search are described. During the initial preparatory phase, a representation of the current search goal is activated. Once visual input has arrived, information about the presence of target-matching features is accumulated in parallel across the visual field (guidance). This information is then used to allocate spatial attention to particular objects (selection), before representations of selected objects are activated in visual working memory (recognition). These four phases of attentional control in visual search are characterized both at the cognitive level and at the neural implementation level. It will become clear that search is a continuous process that unfolds in real time. Selective attention in visual search is described as the gradual emergence of spatially specific and temporally sustained biases for representations of task-relevant visual objects in cortical maps.