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331.
Item response theory (IRT) and categorical data factor analysis (CDFA) are complementary methods for the analysis of the psychometric properties of psychiatric measures that purport to measure latent constructs. These methods have been applied to relatively few child and adolescent measures. We provide the first combined IRT and CDFA analysis of a clinical measure (the Short Mood and Feelings Questionnaire—SMFQ) in a community sample of 7-through 11-year-old children. Both latent variable models supported the internal construct validity of a single underlying continuum of severity of depressive symptoms. SMFQ items discriminated well at the more severe end of the depressive latent trait. Item performance was not affected by age, although age correlated significantly with latent SMFQ scores suggesting that symptom severity increased within the age period of 7–11. These results extend existing psychometric studies of the SMFQ and confirm its scaling properties as a potential dimensional measure of symptom severity of childhood depression in community samples.  相似文献   
332.
A fMRI study of word retrieval in aphasia   总被引:9,自引:0,他引:9  
The neural mechanisms underlying recovery of cognitive functions are incompletely understood. Aim of this study was to assess, using functional magnetic resonance (fMRI), the pattern of brain activity during covert word retrieval to letter and semantic cues in five aphasic patients after stroke, in order to assess the modifications of brain function which may be related to recovery. Four out of five patients had undergone language recovery, according to standard testing, after at least 6 months of rehabilitation. The cerebral activation of each patient was evaluated and compared with the activation pattern of normal controls studied with the same fMRI paradigm. In the patients, the pattern of brain activation was influenced by the site and extent of the lesion, by the degree of recovery of language, as reflected by task performance outside the scanner, and by task requirements. In the case of word retrieval to letter cues, a good performance was directly related to the activation in Broca's area, or in the right-sided homologue. On the other hand, in the case of semantic fluency, the relationship between performance level and activation was less clear-cut, because of extensive recruitment of frontal areas in patients with defective performance. These findings suggest that the performance in letter fluency is dependent on the integrity of the left inferior frontal cortex, with the participation of the homologous right hemispheric region when the left inferior frontal cortex is entirely of partially damaged. Semantic fluency, which engages the distributed network of semantic memory, is also associated with more extensive patterns of cerebral activation, which however appear to reflect retrieval effort rather than retrieval success.  相似文献   
333.
A pure case of autopsy-confirmed dementia with Lewy bodies (DLB) is described. The patient presented with distinctive verbal fluency deficits in the context of mild language impairment, intact recognition memory, and impaired paragraph recall. Neuroimaging (CT and SPECT) showed progressive medial temporal lobe atrophy. Neuropathology revealed Lewy bodies, degeneration in the substantia nigra, nucleus basalis of Meynert (Nakano & Hirano, 1984), and locus ceruleus, but no pathology characteristic of Alzheimer's disease. It is in this sense that the case is "pure" DLB. Early neuropsychological diagnosis of DLB is essential (Salmon et al., 1996) given the potentially fatal hazard of neuroleptics (McKeith et al., 1992) and the difficulties associated with clinical neurological diagnoses (Litvan et al., 1998).  相似文献   
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流畅性可以影响再认,而且仅影响熟悉性加工的观点已得到大量研究的证实。近年一些研究者采用掩蔽启动范式并结合修改的R/K范式、独立判断的R/K范式等实验范式,操控测验项目的流畅性,发现流畅性影响的可能是猜测或者回想加工,因而质疑这个结论。为解释流畅性对再认的影响,流畅性归因理论侧重对流畅性的归因、冲突-归因理论侧重期待流畅性和实际流畅性之间的冲突、预激活-适应模型侧重启动刺激引起的神经活动激活或适应、线索-学习理论侧重流畅性线索的有效性。未来研究应关注流畅性对来源和联结记忆的影响,并考察流畅性对再认的影响在不同年龄人群或遗忘症人群中的表现是否一致。  相似文献   
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Two patterns of data predict that similarity has a positive effect and a negative effect on visual working memory (VWM) processing. We assume that these two empirical outcomes do not distinguish categorical similarity from feature-space proximity, resulting in this divergence. To investigate how categorical similarity and feature-space proximity modulate VWM, we tested memory for an array of pictures drawn from either mixed categories or a single category in which feature-space proximity varied along a morph continuum in a change-detection task. We found that memory under the mixed-category condition was better than that under the single-category condition, whereas memory under high feature-space proximity was superior to that under low feature-space proximity. These patterns were unaffected by manipulations of stimulus type (faces or scenes), encoding duration (limited or self-paced), and presentation format (simultaneous or sequential). These results are consistent with our hypotheses that categorical similarity inhibits VWM, whereas feature-space proximity facilitates VWM. We also found that memory for items with low feature-space proximity benefited more from mixed-category encoding than that for items with high feature-space proximity. Memory for faces benefited more from mixed-category encoding than scenes, whereas memory for scenes benefited more from feature-space proximity than faces. These results suggest that centre-surround inhibition organization might underlie similarity effects in VWM. Centre-surround inhibition organization for complex real-world objects could have both categorical level and feature-space level. The feature-space level might differ by category.  相似文献   
339.
While there is an ample amount of consumer behavior research that recruits processing fluency as an explanatory construct, the question how to best measure the fluency experience has received little attention. Therefore, there is a lack of consistency in measuring the construct, particularly with regard to the use of single‐item versus multi‐item measures. The current research, thus, aims to investigate how processing fluency can be consistently measured across different experimental fluency manipulations and which type of measure has the highest validity. Based on classic scale development procedures, we propose a reliable and valid multi‐item measure and compare this measure against a single‐item measure in terms of predictive validity. We show that both measures mediate the effect of five established fluency manipulations and that the single‐item measure is sufficient. In addition to providing a measure for future research that can be adapted to different empirical settings, we provide empirical evidence on the replicability of fluency effects and on the theoretical conjecture that people have a uniform fluency experience across different manipulations of fluency.  相似文献   
340.
为考察计算流畅性对小学低年级儿童数学焦虑的影响及作用机制,对592名小学二年级儿童的计算流畅性、数学学习兴趣、教师支持和数学焦虑进行测查。结果发现:(1)计算流畅性不仅通过数学学习兴趣间接影响数学焦虑,也可通过数学学习兴趣进而通过教师支持间接影响数学焦虑;(2)对计算流畅性和数学学习兴趣得分进行潜剖面分析,可将儿童区分为三种类型:低能力-低兴趣型、高能力-高兴趣型和低能力-高兴趣型;(3)低能力-低兴趣型儿童的数学焦虑得分显著高于其他两类,而低能力-高兴趣型和高能力-高兴趣型儿童的数学焦虑得分则无显著差异。上述结果表明计算流畅性、数学学习兴趣和教师支持在预防和干预小学低年级儿童的数学焦虑中具有重要作用。  相似文献   
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