Inter-male aggression in mice: Influence of gonadectomy and prior fighting experience

Groups of adult male mice of the Rockland-Swiss strain were paired 0, 2, 7, or 15 times with adult male stimulus animals rendered non-aggressive by extirpation of olfactory bulbs. All animals were castrated and tested until fighting ceased, following which each was given testosterone replacement and tested until fighting was reinstated. More than 50% of mice with no pre-castration fighting experience fought following gonadectomy. Castrated animals permitted 15 pre-castration pairings fought significantly longer than did animals of any of the other treatment groups. Finally, there was no difference among the groups with regard to the latency to resume fighting following the commencement of testosterone replacement. It is concluded that fighting experience enhances the persistence of the behavior following castration.     

Effects of some physiological and pharmacological manipulations on shock- facilitated mouse killing by onychomys leucogaster (Northern grasshopper mouse)

Onychomys leucogaster (northern grasshopper mice) were induced to kill mice with response-contingent shock, and the effects of several physiological, pharmacological, and endocrinological variables were assessed. Lesions of the septum facilitated mouse killing, while lesions of the amygdala abolished spontaneous mouse killing and delayed shock-facilitated killing. Chlorpromazine (2.5–5 mg/kg) and chlordiazepoxide (5–10 mg/kg) facilitated mouse killing on postdrug trials but did not affect killing when the animals were drugged. Adrenalectomy, castration, and castration adrenalectomy did not alter the frequency of kill nor were sex-related differences in killing noted. These results were compared to those found by others studying the effects of lesions and drugs on mouse killing by rats.     

Anxiety: the importunate companion. Psychoanalytic theory of castration and separation anxieties and implications for clinical technique

In this article I consider the implications of our differing psychoanalytic theories of anxiety on clinical technique. Drawing on differentiations between the focus on separation or castration anxiety and the relative neglect of the latter in contemporary writing, I look in detail at two clinical examples of psychoanalysis in borderline young adults to exemplify the issue. 1     

The dangers and deprivations of too-good mothering

The paper explores Winnicott's ideas on the detrimental effects of mothering which is too well adapted to infant needs. Winnicott claimed that such too-good mothering, when pursued beyond the baby's earliest months, led to two possible outcomes: the child would either reject the mother or would remain in a state of arrested development, merged with her. The paper follows the development of a baby girl, observed by the Bick method, and illustrates how her mother's devoted and sensitive care effectively deprived her of the development of some aspects of the sense of self and of possibilities for negotiation, concern and reparation. The baby developed a paranoid orientation and later rejected her mother after the birth of her sister. The paper also mentions the alternative outcome of a persisting state of passive merger with the mother and ends by hoping for further exploration of the means by which some sensitive, responsive parents may inadvertently ‘worse than castrate’ their children by depriving them of an autonomous sense of agency.     

Phallic and seminal masculinity: A theoretical and clinical confusion

Both inside and outside psychoanalysis, the word, 'seminal', is used to praise a creative contribution to science and culture. Rarely, however, does it refer to male procreativity, to the structures and functions that subserve it or to the anxiety related to a threat to it. This situation becomes evident in the concept of castration anxiety, which typically refers, with Freud, to cutting off the penis and not to extirpating the testicles. This phallic theory has been debated, repudiated and ignored. While there is an alternative literature on non-phallic masculinity, it is scattered and rarely refers to seminal function. Freud's theory meets his requirement for a well-articulated representation of absolute loss as an experience, but this clear structure – and its repudiation – obscure the observation and theory of the internal world of the male. I propose the concepts of 'seminal masculinity' and 'seminal castration', which I ground in Melanie Klein's concept of depressive anxiety. I contrast them with phallic masculinity and phallic castration anxiety, which I ground in her concept of paranoid–schizoid anxiety. I argue that they meet Freud's requirement that castration be a potential experience and that understanding masculinity demands such a basis.     

Regional studies of brain biogenic amines in castrated muricidal and non-muricidal wistar rats

Castrated Wistar rats were isolated for 8 months and their muricidal behavior was investigated. Significantly fewer (35%) of such rats became muricidal (CM) compared to controls. The steady-state levels of 5-HT, 5-HIAA, DA, DOPAC, and NE, as well as the changes in synthesis or utilization rats of 5-HT and DA, were analyzed in 15 brain areas derived from CM rats and non-muricidal (CNM) control subjects. In CM rats, higher 5-HT levels were recorded in 5 areas considered to be involved in muricidal behavior: raphe, amygdala, olfactory tubercles, olfactory bulbs, and striatum. The alterations of serotonergic neurotransmission in castrated muricidal rats differ strikingly from those observed in non-castrated muricidal rats. An increase of 5-HT level and in the 5-HT synthesis index as well as a lower 5-HT utilization index were recorded in the raphe of CM rats. Our data suggest that the decrease of 5-HT levels generally said to be the main alteration in the muricidal rat's brain has to be reconsidered. Increased DA levels were observed in CM rats: raphe (50%), amygdala, olfactory tubercles, striatum, and septum (40%), while DA was decreased in cortical areas. There were slight increases of DA synthesis indices in the septum, olfactory tubercles and striatum with a decreased utilization index in the olfactory tubercles. Few alterations in NE levels were observed in CM rats: a decrease in the olfactory tubercles, superior colliculus, and striatum and an increase in temporal cortex. The monoaminergic alterations correlate with the modulation of muricidal behavior. Some areas (the olfactory tubercles, raphe, striatum, and temporal cortex) seem to be particularly involved. © 1992 Wiley-Liss, Inc.     

Case study: Analysis of a traumatized hemophiliac boy

The author presents a case study of a hemophiliac boy in four‐times‐a‐week analysis from the age of four to six and a half years. An extensive narrative of various phases of the analysis including the termination provides the reader access to the material for discussion of therapeutic action. Her analytic technique is based on a developmental point of view and illustrates the use of limits, play, and interpretation based on countertransference. She understands the boy's symptoms of preferring to be a girl, asking to cut his penis off, and wishing to die as defenses against the fear of castration, which in his case is aggravated by the actual threat of repeated medical interventions, and by the underlying fear of a lack of body composition. An unusual feature of the case is the illustration of the symptom, the analysis, and the recovery of the male self, captured in a complex collage that was made over the course of the relatively short analysis.     

Relationship between sexual activity and intraspecific fighting in male mice

Significantly more male mice having cohabited and mated with intact females subsequently displayed intraspecific fighting behavior after castration than males having cohabited with noncycling (ovariectomized) females. Also, intact males that failed to achieve a criterion for aggression during three screening tests subsequently showed a marked increase in fighting after having had copulatory experience relative to males that lived with ovariectomized females. Lastly, spontaneously aggressive males copulated more frequently than nonfighters.     

Reasonable Partiality to Domestic Animals

The paper deals with partiality flowing from special relationships. Two main problems are discussed. The first concerns the relationship between partiality and genuine moral obligations. If partiality can bring about such obligations only if it is reasonable, what requirements should it meet in order to be reasonable? The second problem is one of animal ethics. Can the concept of reasonable partiality help us articulate what is morally at stake in a current discussion about the treatment of domestic animals, viz. the European discussion about the castration of pigs?