全文获取类型
收费全文 | 856篇 |
免费 | 21篇 |
国内免费 | 9篇 |
专业分类
886篇 |
出版年
2024年 | 2篇 |
2023年 | 14篇 |
2022年 | 14篇 |
2021年 | 4篇 |
2020年 | 15篇 |
2019年 | 13篇 |
2018年 | 24篇 |
2017年 | 28篇 |
2016年 | 35篇 |
2015年 | 10篇 |
2014年 | 67篇 |
2013年 | 155篇 |
2012年 | 5篇 |
2011年 | 46篇 |
2010年 | 38篇 |
2009年 | 42篇 |
2008年 | 46篇 |
2007年 | 60篇 |
2006年 | 48篇 |
2005年 | 30篇 |
2004年 | 19篇 |
2003年 | 20篇 |
2002年 | 18篇 |
2001年 | 22篇 |
2000年 | 13篇 |
1999年 | 16篇 |
1998年 | 12篇 |
1997年 | 14篇 |
1996年 | 9篇 |
1995年 | 7篇 |
1994年 | 9篇 |
1992年 | 2篇 |
1991年 | 3篇 |
1990年 | 2篇 |
1988年 | 1篇 |
1986年 | 3篇 |
1982年 | 1篇 |
1981年 | 2篇 |
1980年 | 1篇 |
1979年 | 8篇 |
1978年 | 1篇 |
1976年 | 5篇 |
1975年 | 2篇 |
排序方式: 共有886条查询结果,搜索用时 9 毫秒
181.
血管内皮生长因子(vascular endothelial growth factor,VEGF)是一高度特异作用于内皮细胞的糖蛋白,是目前发现的最重要的肿瘤血管生长因子之一.结直肠癌的生长、侵袭和转移与血管内皮生长因子有密切的关系,VEGF在结直肠癌治疗中的作用日益突出.本文就VEGF的功能、在结直肠癌中的表达和治疗的作用作一综述. 相似文献
182.
Richard Joel Wassersug 《Journal of religion and health》2009,48(3):381-390
Classicists have argued that angels in Christian theology were modeled on the eunuchs of antiquity; with angels providing
the same services to the Lord in Heaven that eunuchs provided to emperors on Earth. I apply this idea toward understanding
the cherubim on the ark in Exodus 25 and the death of Aaron’s sons in Leviticus 10. I also suggest that the angel-eunuch analogy
can help us understand the psychological impact of androgen deprivation therapy on modern prostate cancer patients. Appreciating
this analogy can help prostate cancer patients accept and adapt to the changes they experience.
Dr. Richard Joel Wassersug , PhD, is a Full Professor in Dalhousie University’s Department of Anatomy and Neurobiology, with cross appointments in Biology and Psychology. With coauthors in psychology, anthropology, medicine, and philosophy he now studies the psychological impact of androgen deprivation in historical and contemporary societies. The rationale for this research is to develop strategies for helping men recognize, accept, and adjust to the effects of medical treatments that impact on their gender identity (i.e., sense of masculinity) and sexuality (for example, potency and sex drive). 相似文献
Richard Joel WassersugEmail: |
Dr. Richard Joel Wassersug , PhD, is a Full Professor in Dalhousie University’s Department of Anatomy and Neurobiology, with cross appointments in Biology and Psychology. With coauthors in psychology, anthropology, medicine, and philosophy he now studies the psychological impact of androgen deprivation in historical and contemporary societies. The rationale for this research is to develop strategies for helping men recognize, accept, and adjust to the effects of medical treatments that impact on their gender identity (i.e., sense of masculinity) and sexuality (for example, potency and sex drive). 相似文献
183.
Imagining the Future of Photoacoustic Mammography 总被引:1,自引:0,他引:1
van der Burg S 《Science and engineering ethics》2009,15(1):97-110
How can a realistic ethical imagination about the future of a technology take shape? This article contains a reflection which is based on the experiences of an embedded ethicist in the context of biophysical research conducive to the development of photoacoustic mammography, which is intended for the non-invasive detection of breast cancer. Imagination in this context already informs the activities of the biophysical researchers, but its role is limited: biophysical future scenarios concentrate on the technological advances that photoacoustics could bring about. In this article it is argued that it is advisable to also consider the medical practice and the ways in which this practice is likely to change as an effect of the introduction of photoacoustic mammography into it. On the basis of this more encompassing imaginative endeavor it is possible to get a clearer idea about how new technologies are able to contribute to human well being, which is informative for the setting of research-goals/priorities and a responsible implementation of new technologies into the world. 相似文献
184.
Janice Bowie Barbara Curbow Thomas Laveist Sheila Fitzgerald Kenneth Pargament 《Journal of religion and health》2001,40(4):411-422
In this study, we investigated the relationship between religious coping style and anxiety related to breast cancer and the use of mammography in a sample of African American women. We also assessed the relationship of breast cancer anxiety to related variables such as church affiliation and attendance, church teachings on health, and acceptance of those teachings. 相似文献
185.
食管癌研究的历史回顾和哲学思考 总被引:7,自引:3,他引:4
食管癌研究可分为病因学、发病机制和防治三个部分,涵盖了流行病学、生物化学、病理学、肿瘤学、分子生物学等多个学科。尽管两千多年前,我国学者以开始记载和描述食管癌,但直到近代特别是现代科学技术的进步才对食管癌有了系统的认识。回顾食管癌的研究史,不难看出,正确的研究方法和科学思路在揭示食管癌发病机制和控制食管癌发病率和死亡率中起关键的作用。辨证地剖析机体内部和外界环境之间的关系,人群研究和实验室研究,个体化局部治疗和全身综合治疗,基础和临床研究,传统方法和现代高科技的有机结合,国内外合作研究与小范围研究,研究者与食管癌患者之间的关系等方面的关系,是指导食管癌 研究的重要环节。 相似文献
186.
June A. Peters Carol L. McAllister Wendy S. Rubinstein 《Journal of genetic counseling》2001,10(2):151-168
This is a report of the preliminary findings of a brief exploratory ethnographic study in a cancer diagnosis and treatment clinic. The main research purpose was to explore the meaning of cancer and cancer treatment to patients themselves and to their relatives and close friends. The methods are described in detail in a paper focusing on the experiences of being a novice ethnographer (Peters et al. (2001) J Genet Counsel 10(2):133–150.). The preliminary results of this exploratory fieldwork indicate that the experience of attending a cancer treatment clinic for evaluation and/or treatment is a complex social, emotional as well as medical process for patients and families. Themes with relevance to genetic counselors that emerged from this early observation period included ideas about causes of cancer, the complex nature of families and kinship, coping and support, use of food, and healing. These initial findings have implications for genetic counseling practice and hopefully will stimulate more qualitative social and behavioral research in cancer genetic counseling. 相似文献
187.
Anne E. Kazak Lamia P. Barakat Melissa Alderfer Mary T. Rourke Kathleen Meeske Paul R. Gallagher Avital Cnaan Margaret L. Stuber 《Journal of clinical psychology in medical settings》2001,8(4):307-323
This study presents initial data validating the use of a new instrument, the Impact of Traumatic Stressors Interview Schedule (ITSIS), to assess the occurrence of cancer-related posttraumatic stress in childhood cancer survivors and their mothers. Sixty-six child/adolescent cancer survivors and 64 of their mothers, as well as 130 young adult survivors, completed the ITSIS and other measures of posttraumatic stress and general distress. Five ITSIS factors were identified for the mothers and for the young adult survivors, and three ITSIS factors were identified for the child/adolescent survivors. Factors in all three samples reflected symptoms of posttraumatic distress, concern over medical late effects, communication, and changes in self due to cancer. Only young adult survivors had a factor reflecting a positive engagement with the cancer history. Factors correlated with validation measures in predicted ways. The findings further the conceptualization of posttraumatic stress in pediatric cancer by describing the traumatic experience for survivors and mothers. Comparing factors across samples allows an examination of different influences of cancer within families and over the course of development. 相似文献
188.
This article presents further clinical material from the Paris Psychosomatic School ( Aisenstein, 2006 ). The Freudian foundations of psychosomatics are detailed and post-Freudian developments focusing on the contribution of the Paris Psychosomatic School are outlined, in particular, the somatizing process as a result of regression and the somatizing process as a result of drive unbinding. The authors argue that the latter possibly gives rise to progressive and serious illness leading to death. The relationship of classical psychoanalysis to psychotherapeutic treatment from the angle of the Paris school is commented on. The authors then turn to two clinical presentations of women suffering from breast cancer. The method of evaluating the patients’ capacities for undergoing psychotherapeutic treatment and their mental capacity for healing is discussed. The face-to-face psychoanalytic treatment undertaken with the second case is discussed. Finally, the authors recall Freud’s insistence after 1920 on the opposition of the life drives and the death drives, which placed self-destruction at the centre of psychic functioning. They conclude that current research in biology and medicine, notably research concerning programmed cell death, will converge with psychoanalytic psychosomatics to illuminate somatizing processes and demonstrate the relevance of psychoanalytic treatment to patients who are capable of mental reorganization in the course of their illness and medical treatment. 相似文献
189.
Self-appraisal, coping efforts, muscle function, and activity and severity of disease were examined in out-patients with rheumatoid arthritis, osteoarthrosis or diabetes mellitus. Factor analysis of a 31-item self-appraisal and coping questionnaire yielded eight factors (self-appraisal, acceptance, minimization, planful problem-solving, avoidance, persistence, attribution of responsibility, and support seeking). For the factors of avoidance, minimization, and persistence, as well as for measures of activity and severity of disease, significant differences between the diagnostic groups were found. For patients with rheumatic arthritis, hierarchical regression analysis indicated disease duration to be associated with acceptance and with attribution of responsibility, and disability measures to be associated with self-appraisal. For patients with osteoarthrosis, they showed disability in muscle function to be associated with avoidance, and more negative self-appraisal as well as lower levels of support seeking to be associated with long disease duration. Results are discussed in terms of structural and adaptive defence forms and of adherence to a coping model ("medical model") which tends to foster acceptance and dependency. 相似文献
190.
Deborah L. Miller Sharon L. Manne Kathryn Taylor Jennifer Keates James Dougherty 《Journal of clinical psychology in medical settings》1996,3(2):115-130
This study examined the relations among optimism, coping, functional status, and psychological adjustment in 75 adults diagnosed with cancer. Both the positive and the negative aspects of psychological adjustment were assessed. All participants had been diagnosed with advanced stages of cancer (i.e., Stages II, III, and IV). Participants completed three assessments across a 4-month time period. Both optimism and coping were associated with psychological adjustment, even after controlling for functional status and prior adjustment. Additionally, optimism and coping were differentially related to distress and well-being. Optimism was strongly and positively associated with well-being and inversely related to distress. Escape-Avoidance coping was positively associated with distress and Accepting Responsibility coping was negatively associated with well-being. Comparisons between the current and prior studies indicated that individuals who are diagnosed with more advanced stages of cancer or who have survived bone marrow transplantation exhibit higher levels of optimism than do healthy individuals and individuals with early-stage disease. 相似文献