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591.
Laura A. Berg S. Robert Young Karen A. Brooks Allison M. Davis S. Terry Smith 《Journal of genetic counseling》1996,5(1):27-38
In order to determine the incidence of familial and hereditary ovarian cancer in a referral patient population, we conducted a retrospective study of 44 patients from a consecutive set of 62 patients treated for ovarian carcinoma at the Gynecologic Oncology Clinic at the Richland Memorial Hospital Center for Cancer Treatment and Research between January 1, 1993 and December 31, 1993. In our study of the referred patients, only two (4.55%) reported a history of at least one first-degree relative also being affected with ovarian cancer. However, 13 patients (29.55%) reported a family history consistent with one of the hereditary ovarian cancer syndromes. In addition to having a suggestive family history, these 13 families demonstrated several cardinal features of hereditary cancer syndromes including early onset, bilaterality, multiple primary tumors, and transmission. Race was the only significantly different demographic factor between the hereditary and sporadic ovarian cancer groups. All 13 patients who appeared to have a hereditary form of cancer were Caucasian. 相似文献
592.
Leonard A. Jason Renee Taylor Lynne Wagner Jay Holden Joseph R. Ferrari Audrius V. Plioplys Sigita Plioplys David Lipkin Morris Papernik 《American journal of community psychology》1995,23(4):557-568
Most of the Chronic Fatigue Syndrome (CFS) epidemiological studies have relied on physicians who refer patients having at
least 6 months of chronic fatigue and other symptoms. However, there are a number of potential problems when using this method
to derive prevalence statistics. For example, some individuals with CFS might not have the economic resources to access medical
care. Other individuals with CFS might be reluctant to use medical personnel, particularly if they have encountered physicians
skeptical of the authenticity of their illness. In addition, physicians that are skeptical of the existence of CFS might not
identify cases. In the present pilot study, a random community sample (N=1,031) was interviewed by telephone in order to identify and comprehensively evaluate individuals with symptoms of CFS and
those who self-report having CFS. Different definitions of CFS were employed, and higher rates (0.2%) of CFS were found than
in previous studies. Methodological benefits in using more rigorous epidemiological methods when estimating CFS prevalence
rates are discussed.
The authors appreciate the generous financial support of the CFIDS Association and Minnan, Inc. We also are grateful for many
helpful suggestions provided by Judith A. Richman, William McCready, Wendell Richmond, and Stephen E. Goldston. Finally, we
are very thankful to the many undergraduate volunteers who helped us complete this study, and they include Cheryl Stenzel,
Georgina DeLa Torre, Vickie Chrisos, Don Banik, Hillary Loeb, Leslie Ramesack, Ellen Diamond, Rob Bleeker, Gib Garza III,
Mindy Silverstein, Kadip Sen, Meredith Lombrazo, Brian Miller, Caroline Marsden, Lorraine Whitmore, Stan Gayot, Karen Costakis,
and Dave Sobotka. 相似文献
593.
人格特征对胃癌发病的影响 总被引:12,自引:0,他引:12
使用C型行为特征问卷、生活事件量表和RBC-C_(3b)R、RBC-IC、RCIA、CIC和C_3等免疫功能的检测,调查和检测了30名胃癌患者和50名健康者。结果表明:(1)胃癌组比健康组在焦虑、抑郁、愤怒内泄、控制等方面得分高,在愤怒外泄、乐观、社会支持等方面得分低;(2)胃癌患者在确诊前8年内有76%的患者遇到生活事件,在确诊前3年内有62%的患者遇到生活事件;(3)胃癌组RBC-C_(3b)R含量低,RCIA含量和CIC水平上升。初步结论:胃癌的发生与患者的一些行为特点有关,主要是抑郁并不表达愤怒;生活事件可作为应激源诱发胃癌;其机制可能与免疫功能有关。 相似文献
594.
Frank Baker James Zabora David Jodrey Adrienne Polland Deborah Marcellus 《Journal of clinical psychology in medical settings》1995,2(4):357-372
A sample of 437 patients completed self-report measures of quality of life and social support while they were being evaluated for bone marrow transplantation (BMT) at The Johns Hopkins Oncology Center. Generally, the candidates showed reasonably high levels of quality of life (QOL) on the Satisfaction with Life Domains Scale (SLDS), their present ranking on the Cantril Self-Anchoring Ladder of Life, and their scores on the Bradburn Positive Affect Scale. The level of QOL of these candidates for transplant was significantly related to their level of social support. Both availability and adequacy of social support for these transplant candidates were found to be significantly related to QOL as measured by the SLDS. Availability of social support as measured by patient membership in religious and other organizations was significantly related to Positive Affect but not Negative Affect. The Family APGAR and Relational Support Scales measures of social support were significantly correlated with both Positive and Negative Affect. 相似文献
595.
We surveyed 111 genetic counselors providing cancer risk counseling (CRC) in order to document their billing and record-keeping practices. Of the 75 respondents, billing was generally done under the supervising physician with a wide variation in charges. Follow-up telephone interviews with 28 counselors who charge patients revealed that billing was usually done using the CPT codes for consultations, and the ICD-9 diagnostic codes for cancer (if applicable), a medical complaint, or a family history of cancer code. Most counselors exclude some clinical information from the patient's medical record. In consultation notes, 81% of counselors document a discussion of genetic testing, but only 37% document the patient's actual testing decision, and only 19% document test results. In anticipation of increased referrals for CRC, data are needed on the components of a CRC visit, the amount of time required to provide CRC, patient outcomes measures, and charges and reimbursement. The feasibility and advisability of keeping results separate from the patient's medical record also needs to be addressed. 相似文献
596.
Many studies have reported that individuals frequently over- or underestimate their risk of developing cancer both before and after they attend genetic counseling for breast and/or ovarian cancer. Using a combination of interviews and written questionnaires, we investigated counselees' understanding of their risk of developing cancer before and after genetic counseling. We demonstrate that although 76% of the sample thought that their risk was elevated relative to women in general, only a small proportion (17%) were willing or able to provide a numerical estimate of their risk of developing cancer before they attended the clinic. Following the consultation, 43% indicated that their risk of developing cancer was lower than they had anticipated. Twenty-two percent described their risk in absolute rather than relative terms, i.e., that they would definitely (not) develop cancer in the future. The implications of these findings for further research are discussed. 相似文献
597.
John D. Loeser 《Theoretical medicine and bioethics》1991,12(3):213-225
Chronic pain leads to individual suffering and to major costs for all developed countries. Previous studies suggest that both the incidence of disabling chronic pain and the amount of health care consumption due to chronic pain are rapidly increasing. Western medicine is not only often ineffective but may be one of the causes of this epidemic. This article will address the issue of chronic pain of unknown etiology and has the goals of: (1) identifying the factors which have led to our confusion about this topic, and (2) proposing alternative ways of conceptualizing chronic pain and its ensuing behaviors and social consequences. It is concluded that it is essential to discriminate between tissue damage, pain, suffering, pain behaviors, health care consumption, impairment and disability if one is to develop a meaningful conceptualization of the medical, social, economic and political problems of chronic pain. Successful treatment must be defined in behavioral terms such as restoration of normal activities. Disabling chronic pain is often a sign of overwhelming stress engendered by the individual's failure to cope with the demands of industrialized society. 相似文献
598.
从心血管疾病的美国模式看肿瘤的中国模式 总被引:2,自引:1,他引:1
近年来,心脑血管疾病和癌症的死亡率在世界范围内已上升至前三位。自从美国通过改变生活方式,以控制心血管疾病的方针以来,心血管疾病的患病率减少了50%,死亡率降低了25%,人们称之为心血管疾病的美国模式。与此相应的是上海市癌症俱乐部提出了“群体抗癌”的新模式,倡导了“第四医学”和“第三人生”的新理论,10年努力的结果,使癌症患者的5年生存率延长了3倍,10年生存率延长了2-3倍,创造了癌症康复的中国模 相似文献
599.
Craig A. Mason Derek A. Chapman Keith G. Scott 《American journal of community psychology》1999,27(3):357-381
Epidemiological methodology is used to examine the relationship between early childhood risk factors and future identification as having a Severe Emotional Disturbance or as having an Emotional Handicap (SED/EH) at age 13. Data were obtained from 1979/1980 Florida birth records that were electronically linked with 1992/1993 Florida school records. An epidemiological perspective was chosen due to its ability to model both individual and community-level risk. In regards to increasing an individual's risk of SED/EH, two factors, gender (being male) and low maternal education (mother not completing high school at the time of the child's birth), were found to have particularly strong effects. When examining effects of these risk factors upon overall rates of SED/EH in the community, maternal education and marital status (being unmarried at the time of the child's birth) were associated with a large proportion of the cases. Health/biological markers were moderately associated with SED/EH on the individual level, but were related to a relatively small percentage of cases in the population. In addition, effects varied based upon ethnic/cultural heritage. Researchers are encouraged to consider using an epidemiological perspective and its potential utility in the field of community psychology and public policy is discussed. 相似文献
600.
Josephine Green Martin Richards Frances Murton Helen Statham Nina Hallowell 《Journal of genetic counseling》1997,6(1):45-60
In familial breast/ovarian cancer, the information that the proband is able to supply about other family members is of critical importance for genetic counseling. This frequently requires family communication. Forty-six women attending a cancer genetics clinic were interviewed as part of a longitudinal study. Nearly all reported affected maternal, rather than paternal relatives, which may indicate lack of awareness by women with paternal histories. There was also much more communication among female relatives. Mothers, where they were still alive, were key figures in supplying family information. Although the majority of the sample contacted at least one relative regarding counseling, most named a relative with whom they did not feel able to communicate on this subject. Probands balanced the perceived obligation of passing on information with that of not causing alarm. Communication, both obtaining and giving information, was impeded by adoption, divorce and remarriage, family rifts, and large age gaps between siblings. 相似文献