基因-脑-行为视角下的自伤行为产生机制

自伤是遗传与环境共同作用的结果。目前对于自伤行为的探讨已深入到基因及神经系统层面，基因-脑-行为的综合视角为客观揭示自伤产生机制提供了一条有效途径。本文将在已有研究的基础上，结合分子遗传学和神经生物学的最新成果，对自伤候选基因多态性及其可能的脑机制进行系统阐述，并提出今后应在基因多态性的交互作用及其脑机制、积极环境下自伤行为研究、自伤青少年的追踪研究以及自伤行为的系统性探讨等方面进一步深化。     

Mind matters: A narrative review on affective state-dependency in non-invasive brain stimulation

Variability in findings related to non-invasive brain stimulation (NIBS) have increasingly been described as a result of differences in neurophysiological state. Additionally, there is some evidence suggesting that individual differences in psychological states may correlate with the magnitude and directionality of effects of NIBS on the neural and behavioural level. In this narrative review, it is proposed that the assessment of baseline affective states can quantify non-reductive properties which are not readily accessible to neuroscientific methods. Particularly, affective-related states are theorized to correlate with physiological, behavioural and phenomenological effects of NIBS. While further systematic research is needed, baseline psychological states are suggested to provide a complementary cost-effective source of information for understanding variability in NIBS outcomes. Implementing measures of psychological state may potentially contribute to increasing the sensitivity and specificity of results in experimental and clinical NIBS studies.     

Rethinking Traumatic Brain Injury from Intimate Partner Violence: A Theoretical Model of the Cycle of Transmission

ABSTRACT

Despite growing evidence of the repeated nature of traumatic brain injury (TBI) in women experiencing intimate partner violence (IPV), there is no theoretical model depicting TBIs as a cyclical process throughout a lifetime. Situational analysis methodology was used on interviews with 10 women who self-reported passing out from being hit in the head during an episode of IPV to create a theoretical model depicting the cycle of transmission of TBI. We define the cycle of transmission of TBI as the way that women experience multiple TBIs over the course of their lifetime and how TBI can be perpetuated in a family or community. The cycle begins in childhood or adolescence, when women receive a TBI from abuse, sports, or motor vehicle accident. They enter into abusive relationships with men who are also described as living with a TBI and the women receive other TBIs during this relationship. With repeating head trauma, women described increasing TBI symptoms: problems with memory, cognition, executive functioning, depression, and concentration. If they do seek help, they must choose between healthcare and protective shelter. With either choice, the element of instability could be introduced and the cycle of transmission continues. This theoretical model shows that it is necessary to move beyond individual behaviors to think about how TBIs are transmitted through communities and how untreated symptoms can impact help-seeking behavior and perpetuate other risk factors for receiving a TBI.     

Ten Principles for Interpreting Neuroscientific Pronouncements Regarding Human Nature

As the field of brain research continues to advance, much is being discovered about the various aspects of the brain that are associated with certain feelings, thoughts, and behaviors. However, certain studies, or popularized accounts thereof, overreach in their pronouncements, drawing unwarranted conclusions regarding human nature. There are ten principles that will assist the non‐specialist in critically assessing both now and future discoveries reported from the neurosciences, with a focus on helping theologians using neuroscientific data in multidisciplinary work regarding human nature.     

JAMES B. ASHBROOK AND HIS HOLISTIC WORLD: TOWARD A “UNIFIED FIELD THEORY” OF MIND,BRAIN, SELF,WORLD, AND GOD

James B. Ashbrook's “new natural theology in an empirical mode” pursued an integrated understanding of the spiritual, psychological, and neurological dimensions of spiritual life. Knowledge of neuroscience and personality theory was central to his quest, and his understandings were necessarily revised and amplified as scientific findings emerged. As a result, Ashbrook's legacy may serve as a case example of how to do religion‐and‐science in a milieu of scientific change. The constant in the quest was Ashbrook's core belief in the basic holism of brain, mind, personality, the nature of reality, and the underlying reality of God.     

Involving Police Departments in Early Awareness of Concussion Symptoms during Domestic Violence Calls

ABSTRACT

Police officers around the world respond to and investigate calls regarding domestic violence (DV) daily. Police departments operate with standard protocols, particularly when engaging in investigations that involve allegations of strangulation or sexual assault. Operating under advisement of the Maricopa County Attorney’s Office, the Mesa Police Department (Mesa, AZ) has established protocols for detecting, recording, and prosecuting DV cases that involve strangulation and sexual assault. Allegations of strangulation (defined as impeded breathing) or sexual assault prompt officers to offer a forensic nursing exam (FNE) combined with strangulation treatment by forensic nurses at the Mesa Family Advocacy Center. Recognizing the potential for head injury to the assault victim in all DV situations, including intimate partner violence (IPV), the police department has added concussion-awareness training, as well as a point-of-incident investigative tool for its officers to record neurological function of the victim. Officers were instructed to use the ConQVerge device to measure and record the Near Point of Convergence (NPC) as a test of neurological impairment in suspected head injuries. In this article, we discuss the challenges and opportunities for assisting victims of DV strangulation and sexual assault (including non-DV sexual assault) with on-site assessment and consent for further medical assessment and treatment. Additionally, rates of domestic assault victims that report a crime, but decline to follow through with forensic medical tests, are reported for the first time. Lessons learned from the project that inform strategic operations in this space are offered to other agencies prior to the implementation of similar procedures.     

Fire & Language: The Two-Faced Process of Progress in Deep-Structural Sociocultural Evolution

Abstract

This paper attempts to show how the inherent structure of human becoming is evolutionarily determined to work toward a “meta-system transition” to a higher order of control with a growing risk of extinction as humanity approaches the “event horizon.” The “double helix” of progress technological and social caused manifold cultural surface structures according to the law of increasing entropy, which, however, are mechanically determined to reunite following the same law. Separate individual centers of cybernetic processing thus gradually turn themselves into discursive (“neural”) units, possibly collapsing into a super-conscious single will once information transmission in the network reaches a certain density and noise decreases below a certain threshold.     

Alter Egos: Notes on the basic Processes of specular Identification

Although identity is always dependant on observing minds, identification in physics and biology remains merely external, avoiding therefore the more serious problems of identity which arise in the presence of observed minds. Minds are defined in this paper as specular machines, i.e. systems capable of crossed self‐representations. Specularity is introduced as the primary condition of any objective identification, and self‐identification is presented as the core of specularity. Elementary illustrations are given of the role of specularity in both sociology and psychopathology.