Transcranial magnetic stimulation as a tool for cognitive studies

Transcranial Magnetic Stimulation (TMS) is a tool for the non-invasive stimulation of the human brain. It allows the activation of arbitrary sites of the superficial cortex and, combined with other brain-imaging techniques such as EEG, PET, and fMRI, it can be used to evaluate cortical excitability and connectivity. This is of major importance in, for example, the study of cognitive processes such as language, learning, memory and self-representation, which are thought to be represented in multiple brain areas. The mechanisms of action of TMS are known on a basic level, but its effect on the activation state of brain tissue is still poorly understood. Clinical applications of TMS have also been proposed and guidelines for its safe use drafted.     

从面孔模块到马赛克──视觉特异性加工的脑机制

“脑功能的模块性”是视觉乃至整个认知神经科学的研究热点。特异性的面孔加工模块被当作是认知模块假说的最好证据。但综述跨学科的正反两方面实验证据表明,视觉加工存在特异性,并没有普遍的模块式的亚单元,而是“马赛克”镶嵌式的组构。     

左前额叶参与非相关词对的语义编码过程──来自光学成像的佐证

通过研究左前额叶在非相关同对的语义编码过程中的作用,探讨近红外光学成像技术用于脑高级认知活动检测的可行性。被试在两种实验条件下分别学习视觉呈现的20个汉字非相关词对,要求被试或将词对组成一个有意义的句子(深加工),或判断两个词是否具有相同的结构组合(浅加工)。光学成像器即时记录连续光透过额骨及前额皮层后760nm和850nm的漫射光强变化,以此推测相应脑组织的血容量变化。结果表明,与浅加工相比,左下前额叶在深加工时的血容量增多,尤其是背外侧部分。     

Understanding Biology in Religious Experience: The Biogenetic Structuralist Approach of Eugene d'Aquili and Andrew Newberg

What are the biological bases of religious experience? Are there biological constraints upon or determinants of religious narratives and practices? How does understanding the biology of religious experience inform the ongoing reconstruction of religious rituals and myths? In The Mystical Mind, Eugene d’Aquili and Andrew Newberg address these central questions and others from a distinct perspective called biogenetic structuralism. They propose a model of how brain activity gives rise to mystical experiential states, examine how neurobiological responses to rhythmic behavior form religious ritual, and point toward the development of a megatheology, or a theological system appealing to the widest scope of religious world‐views. This paper is a critical review of d’Aquili and Newberg's exciting work.     

The Biological Basis of Social Interaction

The fact that brain disorder can impair social interactions in different ways suggests that social competence has multiple components that have foundations in brain systems. The physiological basis of one aspect of social cognition, theory of mind, is just beginning to be understood. Brain-imaging studies suggest that a network of areas linking medial prefrontal and temporal cortex forms the neural substrate of mentalizing, that is, representing one's own and other people's mental states. The medial prefrontal areas are prominent also in tasks that involve self-monitoring, whereas the temporal regions are prominent also in tasks that involve the representation of goals of actions. We speculate that the precursors of mentalizing ability derive from a brain system that evolved for representing agents and actions, and the relationships between them.     

Traumatic Brain Injury Outcome in Older Adults: A Critical Review of the Literature

This paper is a critical overview of the literature on older adults' outcome after traumatic brain injury (TBI). Eighteen outcome studies were reviewed. Results indicated that older patients demonstrated an increased risk for negative outcome following TBI when compared to younger patients with similar injury severity. Poorer outcome was characterized by higher mortality rates, decreased likelihood of returning to preinjury living arrangement, and declines in cognitive and affective functioning. In the studies reviewed, discharge destination, global outcome scales, and standardized neuropsychological tests were the primary measures of outcome from elderly TBI. Conceptual and methodological difficulties including variability in the definition of and inadequate measures of recovery from elderly TBI, inadequate control groups, and poor follow-up were discussed. Recommendations for future outcome research to increase uniformity in defining recovery in order to enhance comparability between studies and to tailor cognitive rehabilitation to the special needs of the older TBI patient were provided.     

Proximal and distal effects of play on child compliance with a brain-injured parent.

Individuals with brain injury may experience severe cognitive and other impairments. For brain‐injured parents, such deficits may be associated with child behavior problems, including noncompliance. We assessed the effects of a play period conducted by a brain‐injured father on the compliance of his son, who had become uncooperative with his father after the injury. The child consistently demonstrated improved compliance during proximal and distal compliance sessions that followed father‐son play periods.     

初始信念、组织诱引对员工心理契约变化的影响

心理契约是员工——组织关系的重要形式,组织中的心理契约是发展变化的。该研究采用追踪设计,以189名大学本科毕业生为研究对象,考察员工入职前初始信念和入职后组织提供的诱引因素以及两者之间的交互作用如何影响员工对组织义务感的改变。研究发现：组织支持对关系型义务感和交易型义务感的变化都有明显的影响作用,其对关系型义务感的影响强于对交易型义务感的影响;员工入职前初始信念对员工义务感发展的影响作用受到组织诱引包括工作奖赏和组织支持的调节     

应激对记忆影响的脑科学研究及其教育启示

大量脑科学的研究揭示,应激对与海马相关的陈述性记忆的调节主要通过应激激素,尤其是糖皮质激素的分泌而发生作用,而影响的方向取决于一些调节变量,包括糖皮质激素升高的水平以及记忆的不同阶段等。研究发现基底外侧杏仁核是糖皮质激素对记忆不同阶段产生差异性影响的关键部位。因此,在教育过程中,既要科学地认识应激对记忆的消极影响,又要有效利用应激对记忆产生的调节作用,来提高学生的学习效率。     

Risk Taking in Adolescence: New Perspectives From Brain and Behavioral Science

ABSTRACT— Trying to understand why adolescents and young adults take more risks than younger or older individuals do has challenged psychologists for decades. Adolescents' inclination to engage in risky behavior does not appear to be due to irrationality, delusions of invulnerability, or ignorance. This paper presents a perspective on adolescent risk taking grounded in developmental neuroscience. According to this view, the temporal gap between puberty, which impels adolescents toward thrill seeking, and the slow maturation of the cognitive-control system, which regulates these impulses, makes adolescence a time of heightened vulnerability for risky behavior. This view of adolescent risk taking helps to explain why educational interventions designed to change adolescents' knowledge, beliefs, or attitudes have been largely ineffective, and suggests that changing the contexts in which risky behavior occurs may be more successful than changing the way adolescents think about risk.