Modulation of N400 in chronic non-fluent aphasia using low frequency Repetitive Transcranial Magnetic Stimulation (rTMS)

Low frequency Repetitive Transcranial Magnetic Stimulation (rTMS) has previously been applied to language homologues in non-fluent populations of persons with aphasia yielding significant improvements in behavioral language function up to 43 months post stimulation. The present study aimed to investigate the electrophysiological correlates associated with the application of rTMS through measurement of the semantic based N400 Event-related brain potentials (ERP) component. Low frequency (1 Hz) rTMS was applied to the anterior portion of the homologue to Broca’s area (pars triangularis), for 20 min per day for 10 days, using a stereotactic neuronavigational system. Twelve non-fluent persons with aphasia, 2-6 years post stroke were stimulated. Six participants were randomly assigned to receive real stimulation and six participants were randomly assigned to receive a blind sham control condition. ERP measures were recorded at baseline, 1 week and 2 months subsequent to stimulation. The findings demonstrate treatment related changes observed in the stimulation group when compared to the placebo control group at 2 months post stimulation indicating neuromodulation of N400 as a result of rTMS. No treatment related changes were identified in the stimulation group, when compared to the sham group from baseline to 1 week post stimulation. The electrophysiological results represent the capacity of rTMS to modulate neural language networks and measures of lexical-semantic function in participants with non-fluent aphasia and suggest that time may be an important factor in brain reorganization subsequent to rTMS.     

Portrayal of personality in Victorian novels reflects modern research findings but amplifies the significance of agreeableness

All literature embodies an implicit theory of personality and human nature (Hogan, 1976). The research described here investigates the implicit personality theory embedded in the behavior of 435 characters in 143 canonical Victorian novels. Characters were rated on the Web by 519 scholars and students of 19th-century British literature. Ratings included the characters’ goals, success in achieving goals, mate preferences and strategies, and personality according to the Five Factor Model. Results suggest that novels by Victorian authors largely reflect personality and human nature as understood by modern personality psychology, but Victorian authors amplify the significance of agreeableness and thus, whether intentionally or not, encourage cooperative impulses in readers.     

Liberal bias mediates emotion recognition deficits in frontal traumatic brain injury

It is well-known that patients having sustained frontal-lobe traumatic brain injury (TBI) are severely impaired on tests of emotion recognition. Indeed, these patients have significant difficulty recognizing facial expressions of emotion, and such deficits are often associated with decreased social functioning and poor quality of life. As of yet, no studies have examined the response patterns which underlie facial emotion recognition impairment in TBI and which may lend clarity to the interpretation of deficits. Therefore, the present study aimed to characterize response patterns in facial emotion recognition in 14 patients with frontal TBI compared to 22 matched control subjects, using a task which required participants to rate the intensity of each emotion (happiness, sadness, anger, disgust, surprise and fear) of a series of photographs of emotional and neutral faces. Results first confirmed the presence of facial emotion recognition impairment in TBI, and further revealed that patients displayed a liberal bias when rating facial expressions, leading them to associate intense ratings of incorrect emotional labels to sad, disgusted, surprised and fearful facial expressions. These findings are generally in line with prior studies which also report important facial affect recognition deficits in TBI patients, particularly for negative emotions.     

Differential recruitment of executive resources during mind wandering

Recent research has shown that mind wandering recruits executive resources away from the external task towards inner thoughts. No studies however have determined whether executive functions are drawn away in a unitary manner during mind wandering episodes, or whether there is variation in specific functions impacted. Accordingly, we examined whether mind wandering differentially modulates three core executive functions—response inhibition, updating of working memory, and mental set shifting. In three experiments, participants performed one of these three executive function tasks and reported their attentional state as either on-task or mind wandering at random intervals. We found that mind wandering led to poorer performance in the response inhibition and working memory tasks, but not the set-shifting task. These findings suggest that mind wandering does not recruit executive functions in a monolithic manner. Rather, it appears to selectively engage certain executive functions, which may reflect the adaptive maintenance of ongoing task performance.     

Type of physical exercise and inhibitory function in older adults: An event-related potential study

ObjectivesThe present study was to examine the relationship between exercise type and inhibitory function in older adults using neuroelectric indices.DesignA cross-sectional design was employed in the present study.MethodSixty adults (M = 69.42 years) were categorized into open-skill, closed-skill, and irregular exercise groups according to their history of exercise participation. The participants conducted a flanker task while their behavioral performance and event-related brain potentials were assessed.ResultsThe results indicated that regular exercisers, regardless of exercise type, exhibited a faster reaction time across conditions of the flanker task compared to irregular exercisers. For the P300 amplitude of the open-skill exerciser group, the peak amplitude was larger at the vertex site compared to the frontal site, whereas no site differences were observed in the closed-skill and irregular exerciser groups.ConclusionsThese findings extend current knowledge by suggesting that, for older adults, participation in physical exercise involving increased cognitive demand is associated with better neural efficiency in resource allocation for tasks that require interference control.     

Exploring the interplay between sport modality and cognitive function in open- and closed-skill athletes

The degree to which each sport modality relies on cognitive visual skills is hitherto under-researched. This study sought to further understanding of the relationship between sport modality and visual search ability, visual working memory, and reasoning. Ninety-five participants took part in the present study. In order to assess visual search ability, we employed the Visual Search Task. Visual working memory was assessed through the Corsi Block Tapping – Backwards Task. Reasoning abilities were assessed through the Cognitive Reflection Task. Results indicate that visual search skills appear to benefit to a higher extent from open-skill sports when compared to closed-skill sports. It is important to emphasize, however, that this result was associated with a small effect size. Moreover, the present findings indicate that closed-skill athletes do not differ in terms of visual search abilities, working memory, and reasoning abilities when compared to control individuals.     

挫折情境下自我肯定对执行功能的影响

为探讨挫折情境下自我肯定对执行功能的影响,创设挫折和非挫折情境,采用价值观自我肯定干预,通过Stroop范式和2-back范式分别测量抑制控制和工作记忆的刷新能力。结果发现,挫折情境下的Stroop任务和2-back任务反应时均高于非挫折情境;挫折情境下自我肯定组在Stroop任务和2-back任务上的反应时均显著低于非自我肯定组,而非挫折情境下两组的反应时没有显著性差异;Stroop效应量在情境与肯定条件上的交互作用不显著。结果表明挫折降低了执行功能的任务表现,自我肯定干预能够改善挫折情境下执行功能相关的任务成绩,促进了个体对工作记忆任务的刷新能力和Stroop任务的认知表现,但对抑制控制能力的改善没有明显作用。