我国人体器官捐赠移植立法问题研究

通过对我国人体器官捐赠移植立法的必要性和立法模式问题,以及我国人体器官捐赠移植法的体系和基本原则进行深入研究,指出我国人体器官捐赠移植立法宜采用统一立法模式,并遵循知情同意、人民健康第一、效用与公平、规范程序与便于操作、违法必究五项原则。     

建立鼻腔结构与功能自适应生物力学模型在鼻科疾病中的作用

鼻腔结构在与鼻腔物理力学环境发生交互关系时,能够根据周围环境调整自身结构和形状,即所谓鼻腔结构与功能自适应性.鼻腔结构与功能自适应生物力学模型模拟鼻腔结构异常产生功能障碍所继发的上呼吸道疾病发生发展过程,为鼻科某些常见病的发生发展过程进行量化分析,为鼻内窥镜手术在恢复重建鼻腔结构功能方面临床决策提供依据.     

论人体肾脏捐献中的合理补偿原则

无偿捐献作为当前获取肾脏的伦理原则,是最没有争议、最理想的,但是依靠单纯的无偿捐献所获器官远远不能满足医疗的需求。合理补偿原则既可以有效增加供体数量,又不违背伦理学原则,而且更具有道德上的广泛性和现实的可行性。相信合理补偿原则的实施将会大大促进我国器官移植事业的发展。     

我国人体器官移植的社会支持系统研究

供体来源不足严重制约了我国器官移植事业的发展。有鉴于此,建立一个非技术的人体器官移植的社会支持系统对促进我国器官移植事业的发展将具有重要意义。通过对该系统各组成部分如法律法规系统、组织管理系统、宣传教育系统、补偿系统的研究,旨在对我国器官移植事业的发展有所裨益。     

Ethical and Religious Aspects of Gamete and Embryo Donation and Legislation in Iran

During recent decades, new assisted reproductive technologies (ARTs) have improved significantly, but their ethical, social, psychological, religious and legal aspects are blurred and need further research. New techniques using donor sperm or egg allow for third party involvement in the procreation process, which has created new hope for infertile couples. The corresponding clinical applications also raise new religious questions, which require appropriate interpretation in order to make their use possible, particularly in religious communities. In this paper, we discuss the most important ethical issues and the Islamic view of third party reproduction. Likewise, the current method of third party reproduction in Iran will be described, and the advantages and disadvantages of the Act of Embryo Donation to Infertile Spouses will be stated. Consideration of this outlook could generate inspiration in many Islamic countries.     

骨源性因子ucOCN在运动抗抑郁中的作用机制

羧化不全骨钙素(ucOCN)是骨中成骨细胞分泌的特异性蛋白,因其在调控神经发育、神经可塑性等中的重要角色而受到神经科学领域关注。"骨-脑"串联"对话"是骨内分泌-神经介导的应答系统,ucOCN透过血脑屏障后介导单胺类神经递质、神经内分泌、神经免疫、神经再生及基因表达等机制,进而作用于海马CA3区、扣带回等脑区功能发挥来调节抑郁发生及改善。而ucOCN作为骨源性力学刺激敏感基因,运动上调其表达后进入血液循环,通过介导5-HT/GABA分泌、HPA轴功能、炎症反应、神经营养因子(BDNF等)表达或信号途径(如GSK3β/β-catenin、TLR4/miR-223/NLRP3等)激活等来实现"骨串联脑",发挥运动抗抑郁作用。通过对骨源性因子ucOCN介导脑区功能变化从而实现运动抗抑郁的作用机制进行探讨、梳理,一方面有助于更深入了解骨内分泌功能,另一方面为抑郁发生、改善和运动抗抑郁研究提供新的理论基础和研究思路。     

在校大学生捐精现状调查分析

了解在校大学生对捐精、精子库及供精人工授精后代的认知及其影响因素。对河南省4所高校在校学生发放“河南省在校大学生捐精认知调查问卷”进行调查，并进行统计学分析。结果显示，大多数学生知道捐精，但了解程度不够。男生、独生子女、医学生、城市学生对捐精知识的认知程度较高；影响捐精的主要因素为捐精知识的宣传程度、捐精对健康的影响等；担心个人隐私泄露、后代之间恋爱或结婚是在校大学生不支持捐精的主要原因。     

精子捐赠与伦理

引起男性不育的一个重要原因是无精症、死精症。精子捐赠的出现为这些患者带来了福音,使其享受天伦之乐成为可能,但同时也带来了一系列伦理学、社会学上的问题,包括子代的知情权问题、近亲结婚问题、家庭内部矛盾问题等等。因此要准确认识、运用和完善新的医学技术,并对其进行伦理和法律的规范,防止滥用。     

传统与改良鼻内镜下鼻骨复位术的病例对照研究

比较传统与改良鼻内镜下鼻骨复位术两种手术方式,探讨改良鼻内镜下鼻骨复位术的可行性与优势所在。局部麻醉下分别采用传统与改良鼻内镜下鼻骨复位术对闭合性单纯鼻骨骨折及部分合并鼻中隔骨折的患者进行复位后,比较两种手术方式患者的复位效果、术中出血、术后不适及住院时间。改良鼻内镜下鼻骨复位术较传统鼻内镜下鼻骨复位具有麻醉效果好、鼻...     

Kidney Transplants From Young Children and the Mentally Retarded

Kidney donation by young children and the mentally retarded has been supported by court decisions, arguments based on obligations inherent in family relationships, an array of contextual factors, and the principle of beneficence. These justifications for taking organs from people who cannot protect themselves are problematic and must be weighed against our obligation to protect the vulnerable. A compromise solution is presented that strongly protects young children and the mentally retarded but does not abdicate all responsibility to relieve suffering. Guidelines are proposed that prohibit the retrieval of kidneys from young children and the mentally retarded but permit one exception. They would allow retrieval of a kidney when the consequence to a first order relative with whom the donor has a meaningful and valuable relationship is otherwise imminent death. This would be done in accordance with additional guidelines that minimize harm to the donor. Since most patients with end stage renal disease can be maintained on dialysis the need for a kidney to prevent death should be an uncommon occurrence. This compromise is proposed as a solution to a dilemma that exists because two ethical principles are in conflict and one cannot be honored without violating the other.