《黄帝内经》时间医学思想对急性心肌梗死时间节律的解释

《黄帝内经》“天人相应”理论比较完备地奠定了中医关于人体生物节律知识的基础,强调人体自然节律与四季日月昼夜节律之间的密切关系。在急性心肌梗死发病呈现显著的时间节律特征,以中医时间学理论进行解释,充分掌握急性心肌梗死发病的规律性,指导高危人群合理作息,减少急性心梗的发生。     

SPECIES,TEPEES, SCOTTIES,AND JOCKEYS: SELECTED BY CONSEQUENCES

“Ideas are like species: they must evolve.” This claim forms the conceptual core of an engaging book by Jonnie Hughes (2011), On the Origin of Tepees. Hughes asks: If evolution by natural selection explains the origin of the human species, then does selection by consequences also explain the origin of what we humans make and do? This question prompts consideration of three important analogies: between natural selection and artificial selection, between the law of natural selection and the law of effect, and between biological evolution and cultural evolution. These analogies in turn stimulate examination of the notions of purpose, design, and agency. Finally, discussion moves to the selectionism of Darwin and Skinner; although still controversial, this view remains the best way for natural science to understand the origins of adaptive behavior.     

Temporal perception is enhanced for goal-directed biological actions

ABSTRACT

Research into the visual perception of goal-directed human action indicates that human action perception makes use of specialized processing systems, similar to those that operate in visual expertise. Against this background, the current research investigated whether perception of temporal information in goal-directed human action is enhanced relative to similar motion stimuli. Experiment 1 compared observers’ sensitivity to speed changes in upright human action to a kinematic control (an animation yoked to the motion of the human hand), and also to inverted human action. Experiment 2 compared human action to a non-human motion control (a tool moved the object). In both experiments observers’ sensitivity to detecting the speed changes was higher for the human stimuli relative to the control stimuli, and inversion in Experiment 1 did not alter observers’ sensitivity. Experiment 3 compared observers’ sensitivity to speed changes in goal-directed human and dog actions, in order to determine if enhanced temporal perception is unique to human actions. Results revealed no difference between human and dog stimuli, indicating that enhanced speed perception may exist for any biological motion. Results are discussed with reference to theories of biological motion perception and perception in visual expertise.     

The Structure of Evolutionary Theory : on Stephen Jay Gould's Monumental Masterpiece

Stephen Jay Gould's monumental The Structure of Evolutionary Theory “attempts to expand and alter the premises of Darwinism, in order to build an enlarged and distinctive evolutionary theory … while remaining within the tradition, and under the logic, of Darwinian argument.” The three branches or “fundamental principles of Darwinian logic” are, according to Gould: agency (natural selection acting on individual organisms), efficacy (producing new species adapted to their environments), and scope (accumulation of changes that through geological time yield the living world's panoply of diversity and morphological complexity). Gould's efforts to contribute something important to each of these three fundamental components of Darwinian Theory are far from successful.     

Children's Judgments of Certainty and Uncertainty on a Problem Where the Possible Solutions Differ in Likelihood

In this study the author examined why children and adults think they need to eat. Preschoolers through adults were provided with physiological, social, psychological, and routine causes for eating breakfast, lunch, snack, and dinner, and were asked to either agree or disagree with the causal responses provided. A 4 Reason × 4 Meal repeated measures analysis of variance revealed significant main effects for meals and reasons, as well as significant Meal × Reason and Meal × Reason × Grade interactions. The effect sizes ranged from 0.1 to 0.7. Across all age groups, participants acknowledged physiological needs and desires (fulfilling hunger and needs to stay healthy) and routine (e.g., it is dinner time) as the primary causes for eating breakfast, lunch, and dinner. However, for snack physiological needs were the primary reason. Second-grade students onward spontaneously produced biological justifications such as the need for energy and nutrition as important reasons for food consumption. These results lend support to the developmental model that children's and adults’ understanding of eating changes in middle childhood.     

The concept of evolution and revolution

We hypothesize that there exist certain similarities between the strategies adopted by a biological organism, an individual or a social group, when faced by an aggressor. These strategies consist in either minimizing the aggression or else combating it immediately, in order to preserve, in the short term, the identity of the system under attack. One of the strategies commonly adopted for this purpose is retrocession, permitting the biological, neurobiological organism, or the social individual or group to elude certain environmental elements and return to a situation in which other escape routes may be taken.

In the long term, preservation of the external identity is accomplished by modification of the internal identity. Man uses in vivo or, after “extrusion,” ex vivo immunizing and cognitive functions to cope with the environment. He is thus able to create, ex vivo, therapeutic techniques by manipulating internal identity. In order to accomplish this, a profound knowledge is needed, at the level of each individual, of the functional mechanisms of biological and neurobiological identities.

Though social and biological sciences are progressing, they have great difficulties in finding the common language necessary to communicate productively. Analogies between these two domains, that we shall attempt to illustrate, may contribute to facilitating such communication.     

Organisms,machines, and societies: From the vertical structure of adaptability to the management of information

The adaptability of organisms and human societies depends on the synergistic orchestration of processing modes at many different levels of organization, each with unique informational characteristics. Digital information technology is a narrow transect of this spectrum. Adaptability theory provides a tool for analyzing the interactions between these fundamentally different modes of processing and for delineating the factors that can lead to either positive or negative consequences for human life.     

Economic and biological influences on key pecking and treadle pressing in pigeons

Pigeons were studied on a two-component multiple schedule in which the required operant was, in different conditions, biologically relevant (i.e., key pecking) or nonbiologically relevant (i.e., treadle pressing). Responding was reinforced on a variable-interval (VI) 2-min schedule in both components. In separate phases, additional food was delivered on a variable-time (VT) 15-s schedule (response independent) or a VI 15-s schedule (response dependent) in one of the components. The addition of response-independent food had different effects on responding depending on the operant response and on the frequency with which the components alternated. When components alternated frequently (every 10 s), all pigeons keypecked at a much higher rate during the component with the additional food deliveries, whether response dependent or independent. In comparison, treadle pressing was elevated only when the additional food was response dependent; rate of treadling was lower when the additional food was response independent. When components alternated infrequently (every 20 min), pigeons key pecked at high rates at points of transition into the component with the additional food deliveries. Rate of key pecking decreased with time spent in the 20-min component when the additional food was response independent, whereas rate of pecking remained elevated in that component when the additional food was response dependent. Under otherwise identical test conditions, rate of treadle pressing varied only as a function of its relative rate of response-dependent reinforcement. Delivery of response-independent food thus had different, but predictable, effects on responding depending on which operant was being studied, suggesting that animal-learning procedures can be integrated with biological considerations without the need to propose constraints that limit general laws of learning.