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41.
A cellular analogue of operant conditioning.   总被引:2,自引:2,他引:0       下载免费PDF全文
Using the hippocampal-slice preparation, we attempted to model operant conditioning in vitro by reinforcing pyramidal cell bursting responses with local micropressure applications of transmitters and drugs. The same injections were administered independently of bursting to provide a "noncontingent" control for direct pharmacological stimulation or facilitation of firing. The results suggested that the bursting responses of individual CA1 pyramidal neurons may be reinforced in a dose-related manner by response-contingent (but not noncontingent) injections of dopamine and the selective dopamine D2 agonist, N-0923. N-0924, a stereoisomer of N-0923 that is largely devoid of D2-agonist activity, failed to reinforce CA1 bursting. Burst-contingent injections of the excitatory neurotransmitter glutamate also failed to reinforce CA1 bursting; indeed, the glutamate applications (whether contingent or random) reduced the likelihood of bursts while increasing the frequency of solitary spikes. Reinforcement delays exceeding 200 ms largely eliminated the reinforcing efficacy of the D2 agonist N-0437 in CA1 operant conditioning. The results are consistent with the suggestion that the behaviorally reinforcing effects of dopaminergic agents can be modeled in vitro in the hippocampal-slice preparation.  相似文献   
42.
证素辨证新体系的内容及科学意义   总被引:31,自引:0,他引:31  
提取并规范50项辨证要素,构建起证素辨证新体系,是继承基础上的创新.证素的纲领性与组合的复杂性,是科学的认知论,符合中医辨证思维规律.  相似文献   
43.
Recently Kretchmar attempted to apply and to explore Husserl’s transcendental phenomenological method in relation to clarifying, in the context of sport particularly, the main features of competition. He concludes with the strong claim that competition is unintelligible unless understood in relation to the four elements of plurality, comparison, normativity, and disputation. Roughly, the idea is that competition needs to be understood as a context in which more than one competitor is involved; where competitors are compared; that comparisons are evaluations of their performance/entry in the competition; and that the expected result of the latter is a matter of dispute between or among contestants. In investigating these points some refinement of this basic outline is attempted against occasional reference to others who in the past made similar claims about the conditions of competition. I conclude that Kretchmar’s claims are mistaken.  相似文献   
44.
从《太玄》看扬雄的人性论思想   总被引:1,自引:0,他引:1  
一般讲扬雄的人性论,都以《法言》为依据,认为他是“善恶混”派的代表.并认为他的人性论缺乏内在超越的根据,比较接近于荀子。本文认为《太玄》中蕴涵丰富的人性论思想,研究扬雄的人性论,应以《太玄》为基础。扬雄的人性论本于其天道观,有很强的超越性,扬氏以五行为架构,提出了非常具体的超越途径,其思想接近于性善说.  相似文献   
45.
This study examined the effect of a principle of social influence—authority—on the informational elements in an investigative interview. Community participants told the truth or lied about a mock crime in a high or low authority context. Informational elements were coded from their oral responses in the interviews and written responses in a statement prior to the interviews. Rapport was rated by the interviewers and participants. The authority condition produced effects on the informational elements in both the interviews and written statements but mainly for truth tellers. Rapport also had direct effects on the informational elements but authority did not affect rapport and rapport did not mediate the effect of authority on the informational elements. These findings had theoretical, empirical, and practical implications.  相似文献   
46.
Benjamin Schnieder 《Synthese》2008,162(1):101-115
The Conjunction Principle says, roughly, that if the truth of a conjunction can be brought about, then the truth of each conjunct can be brought about. The current essay argues that this principle is not valid. After a clarification of the principle, it is shown how a proper understanding of the involved notions falsify the principle. As a corollary, a recent attack on van Inwagen’s Consequence Argument will be rebutted, because it relies on the invalid conjunction principle.  相似文献   
47.
Abstract

Age-related EEG activity change is a prominent feature that reflects the functional development of the brain. The current study investigated the beta and mu rhythms of 16 children (7.7 ± 1.5 years, 5 to 9.6 years) and 13 adults when a self-determining arm motion was performed. The results indicated that mu power was decreased during movement and returned to baseline level after the movement for both children and adults. However, although a decrease in beta power was observed for both children and adults during movement, the post-movement beta power rebound (PMBR) was observed in adults but not in children. These results suggest that motor-related mu suppression develops early in children; PMBR develops later and may be associated with a more prolonged motor development process.  相似文献   
48.
49.
藏明 《管子学刊》2011,(1):37-41,69
鲁国与齐国由于地理环境、经济发展状况以及统治政策的不同,造成了鲁学与齐学在诸多方面存在差异。但是到了战国中后期,阴阳家邹衍对鲁学与齐学进行了兼采,形成了独具特色的阴阳五行学说。特别是其五德终始说,既对稷下的学术著作《黄帝四经》、《管子》有所借鉴,又对鲁学的主体儒学的仁义思想、经世致用理论有所吸收,进而使鲁学与齐学达到了初步的融通。  相似文献   
50.
孙超 《管子学刊》2011,(1):64-69
《孟姜女传说》是中国四大民间传说之一。2006年山东淄博将其申报为国家级非物质文化遗产后,就其真正的归属地问题却产生了争议。通过文献考索与田野调查,我们认为:齐鲁,特别是淄博泰山齐长城遗址及周围地区是孟姜女传说的发源地。秦始皇之所以进入《孟姜女传说》,其直接因素是他修了"万里长城",而深层原因是他的齐鲁文化情结。"文化素"是波亚托斯提出的概念,指的是通过符号感觉到或认识到的文化单位。从"礼义"、"歌哭"等文化素分析来看,齐鲁文化是《孟姜女传说》最核心的精神内核,齐鲁是它的文化出生地及传播的中心地带。  相似文献   
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