三维适形放疗治疗晚期腹部恶性肿瘤的临床受益和毒副反应

为观察三维适形放疗治疗晚期腹部恶性肿瘤的临床受益情况和毒副反应。对38例晚期腹部恶性肿瘤患者进行三维适形放疗,疗中和疗后进行临床受益情况和毒副反应的观察和评价。结果临床受益情况：有效为28．9％,稳定为42．1％,疼痛缓解率为28．9％;毒副反应主要为骨髓抑制、胃肠道反应、生化指标改变,除少数病例出现Ⅳ度生化指标改变外,其余均在Ⅲ度以下。结论三维适形放疗可以提高晚期腹部恶性肿瘤患者的生存质量,毒副反应轻微,是一种有效的姑息治疗手段。     

经济学评价在临床决策中的应用探讨

医生在临床工作中做出明确诊断,并据此给予有效的处理均属于决策过程。制定决策的整个过程,同时也是进行决策思维的过程。近年来,高新技术的迅猛发展以及医疗费用急剧增加,使制定决策更加复杂。如何进行正确的决策思维,做出最切实可行的和最佳的决策,对避免决策的盲目性具有重要的现实意义。     

Action naming in anomic aphasic speakers: effects of instrumentality and name relation

Many studies reveal effects of verb type on verb retrieval, mainly in agrammatic aphasic speakers. In the current study, two factors that might play a role in action naming in anomic aphasic speakers were considered: the conceptual factor instrumentality and the lexical factor name relation to a noun. Instrumental verbs were shown to be better preserved than non-instrumental verbs in a group of anomic aphasic speakers but not in a group of Broca's aphasic speakers. Name relation to a noun improved the performance of the anomic aphasic speakers as well. Again, no effect was found in the group of Broca's aphasic speakers. Verbs with a name relation to a noun were better retrieved in action naming than verbs without a name relation. These findings are discussed in terms of the spreading activation theory of Dell. (Dell, G. S. (1986). A spreading activation theory of retrieval in sentence production. Psychological Review 93, 283-321.).     

Do age-related word retrieval difficulties appear (or disappear) in connected speech?

We conducted a comprehensive literature review of studies of word retrieval in connected speech in healthy aging and reviewed relevant aphasia research that could shed light on the aging literature. Four main hypotheses guided the review: (1) Significant retrieval difficulties would lead to reduced output in connected speech. (2) Significant retrieval difficulties would lead to a more limited lexical variety in connected speech. (3) Significant retrieval difficulties would lead to an increase in word substitution errors and in pronoun use as well as to greater dysfluency and hesitation in connected speech. (4) Retrieval difficulties on tests of single-word production would be associated with measures of word retrieval in connected speech. Studies on aging did not confirm these four hypotheses, unlike studies on aphasia that generally did. The review suggests that future research should investigate how context facilitates word production in old age.     

The Mediating Effects of Benefit Finding on the Relationship Between the Identity Centrality of Negative Stressful Events and Identity Achievement

Which types of benefit finding in negative events central to identity lead to higher identity achievement? This study examined the relationships between the identity centrality of negative events, benefit finding, and identity achievement, with consideration of differences between benefit-finding domains. Participants included 245 undergraduates, who recalled a previous negative event and completed the Identity Scale, Centrality of Event Scale, and items regarding benefit finding. Path analysis showed that benefit finding regarding personal growth consistently correlated with identity achievement, while the effects of recognizing warmth in others were unstable depending on event category. The findings demonstrated the role of benefit finding regarding personal growth in promoting identity achievement and buffering the original adverse impact of negative events on identity.     

Individualism–collectivism and organ donation intentions

This article investigates the impact of individualism–collectivism on a person's willingness to donate organs. In Study 1, an online survey showed that individualism–collectivism was significantly and positively associated with participants' willingness to register as organ donors while perceived benefit mediated this relationship. Study 2 demonstrated the causal effect of individualism–collectivism on organ donation intentions using a priming technique. Participants primed with collectivism were more likely to register as organ donors than those primed with individualism. Our findings provide unique insights into whether cultural values (i.e., individualism–collectivism) can predict people's organ donation intentions.     

Thinking Inside the Tool Box: Creativity,Constraints, and the Colossal Portraits of Chuck Close

This article presents a problem‐solving model to examine the often problematic relationship between expertise and creativity. The model has two premises, each the opposite of a common cliché. The first cliché asserts that creativity requires thinking outside‐the‐box. The first premise argues that experts can only think and problem solve inside the tool boxes of their expertise. The second cliché, that creativity requires freedom from constraints, points to the problem with expertise. Free to do anything, experts repeat what has worked best in the past. A solution is suggested by the second premise: to circumvent the liabilities of expertise, creativity requires constraints of a particular paired kind. The model is introduced as an expansion of prior process models focused on problem identification and construction. Problem‐finding is reanalyzed as constraint‐finding. A case study shows how one recognized creator, painter Chuck Close, uses constraints as a tool to solve the expertise‐creativity problem.     

责任共担促进新手的互动决策获益：超扫描研究

采用基于近红外脑成像的超扫描技术, 考察了责任共担(即共同承担决策结果)对个体(专家和新手)的互动决策获益(即互动决策后个体的能力提升)的影响及脑机制。结果显示, 相比于非责任共担, 责任共担条件下新手的互动决策获益更高, 其与互动同伴在额极区域存在增强的脑间活动同步性; 并且, 额极的脑间活动同步性可预测新手的互动决策获益。综上, 责任共担可以有效促进新手的互动决策获益, 额极脑间活动同步性可能是潜在的脑机制。     

Creating analysts, creating analytic patients

This paper applies a contemporary, 'two-track'- transformational as well as archaeological - perspective on psychoanalytic process to clinical issues in the creation of analytic patients: case finding, recommending analysis, and recommending and negotiating the intensification of frequency of sessions in analytic psychotherapy. Central importance is assigned to the role of the mind and analytic identity of the analyst, including the analyst's capacity to maintain an internal analytic frame and analyzing attitude from the very first contact with the patient and throughout the treatment, the analyst's confidence in and conviction about the usefulness of analysis for a given analytic dyad and the role of the analyst's theory, which must be broad and consistent enough to allow the analyst to feel that he or she is operating analytically when addressing non-neurotic (unrepresented and weakly represented mental states) as well as neurotic structures.     

From Walls to Windows: Using Barriers as Pathways to Insightful Solutions

The purpose of this study was to explore and develop a conceptual model for how individuals unlock insight. The concept of insight — the ‘out of the box’ or ‘aha!’ solution to a problem — offers a framework for exploring and understanding how best to enhance problem solving skills due to the cognitive shift insight requires. Creative problem solving (CPS) is inherent to a variety of performance realms including effective decision making, innovation, and organizational development; however, related processes of insight, innovation and creativity remain intangible. The model, based on a review of the problem solving literature, proposes that insight involves a five stage, cyclical process emerging as: primary appraisal of the problem, secondary appraisal based on prior knowledge, initial focus, problem representation, and solution generation when, if no solution is found, the cycle begins again. The research has implications for individual, team and organizational settings suggesting that performance on a wide variety of problems may be improved by utilizing an integrated focus rather than a barrier or goal focus alone.