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161.
A common assumption is that phonetic sounds initiate unique processing in the superior temporal gyri and sulci (STG/STS). The anatomical areas subserving these processes are also implicated in the processing of non-phonetic stimuli such as music instrument sounds. The differential processing of phonetic and non-phonetic sounds was investigated in this study by applying a “sound-morphing” paradigm, where the presence of phonetic features were parametrically varied, creating a step-wise transition from a non-phonetic sound into a phonetic sound. The stimuli were presented in an event-related fMRI design. The fMRI-BOLD data were analysed using parametric contrasts. The results showed a higher sensitivity for sounds containing phonetic features compared to non-phonetic sounds in the middle part of STG, and in the anterior part of the planum temporale (PT) bilaterally. Although the same areas were involved in the processing of non-phonetic sounds, a difference in activation was evident in the STG, with an increase in activation related to increment of phonetic features in the sounds. The results indicate a stimulus-driven, bottom-up process that utilizes general auditory resources in the secondary auditory cortex, depending on specific phonetic features in the sounds. 相似文献
162.
Naeser MA Martin PI Theoret H Kobayashi M Fregni F Nicholas M Tormos JM Steven MS Baker EH Pascual-Leone A 《Brain and language》2011,119(3):206-213
This study sought to discover if an optimum 1 cm2 area in the non-damaged right hemisphere (RH) was present, which could temporarily improve naming in chronic, nonfluent aphasia patients when suppressed with repetitive transcranial magnetic stimulation (rTMS). Ten minutes of slow, 1 Hz rTMS was applied to suppress different RH ROIs in eight aphasia cases. Picture naming and response time (RT) were examined before, and immediately after rTMS. In aphasia patients, suppression of right pars triangularis (PTr) led to significant increase in pictures named, and significant decrease in RT. Suppression of right pars opercularis (POp), however, led to significant increase in RT, but no change in number of pictures named. Eight normals named all pictures correctly; similar to aphasia patients, RT significantly decreased following rTMS to suppress right PTr, versus right POp. Differential effects following suppression of right PTr versus right POp suggest different functional roles for these regions. 相似文献
163.
Rothwell JC 《Human movement science》2011,30(5):906-915
Transcranial magnetic stimulation is increasingly used as a tool to explore cortical motor function in healthy subjects and in patients with neurological disease or injury. This review describes a “twin coil” TMS approach that allows investigation of time related changes in functional connectivity between primary motor cortex and other areas in preparation for a forthcoming movement. Investigations into premotor–motor interactions show that these are specific to the type of task that is performed as well as the muscles used to control the movement, allowing us to monitor information flow within motor networks with millisecond time resolution. 相似文献
164.
Since about two decades neuroscientists have systematically faced the problem of consciousness: the aim is to discover the neural activity specifically related to conscious perceptions, i.e. the biological properties of what philosophers call qualia. In this view, a neural correlate of consciousness (NCC) is a precise pattern of brain activity that specifically accompanies a particular conscious experience. Almost all studies aimed at investigating the NCC have been carried out in the visual system. One of the most promising paradigms is based on sensory stimuli which elicit bistable percepts, as they allow to decouple subjective perception from the characteristics of the physical stimulation. Such kind of perception can be produced in the visual modality by using particular images (e.g. Rubin's vase/face figure) or by presenting two dissimilar stimuli separately to the two eyes (binocular rivalry). The stimuli compete for perceptual dominance and each image is visible in turn for a few seconds, while the other is suppressed. The use of this methodology has led to important findings concerning visual consciousness, which are briefly discussed. For the investigation of auditory consciousness, a similar stimulation paradigm can be achieved by using dichotic listening, consisting in two different stimuli presented each to one ear, which compete for perception (binaural rivalry). The principal aim of the present mini-review is to discuss the few contributes facing the issue of auditory consciousness and to advance the use of dichotic listening and binaural rivalry as valid tools for its investigation. 相似文献
165.
HAMIT COSKUN Ph.D. 《创造性行为杂志》2011,45(1):59-75
The present experiment examined whether or not the type of associations (close (e.g. apple‐pear) and distant (e.g. apple‐fish) word associations) and memory instruction (paying attention to the ideas of others) had effects on the idea generation performances in the brainwriting paradigm in which all participants shared their ideas by using paper slips (Paulus & Yang, 2000). All participants were randomly subjected to exercising on either close or distant word associations ten minutes before the brainstorming session started. The findings showed that exercising on the close associations prior to the brainstorming session led to the generation of more unique ideas, category scanning, and depth of ideas than exercising on the distant ones in a subsequent brainstorming task. Memory instruction led to the generation of fewer ideas than no memory instruction. These findings were discussed from the aspect of the associative memory approach and cognitive stimulation approaches. 相似文献
166.
Esther M. Albers J. Marianne Riksen-Walraven Carolina de Weerth 《Infant behavior & development》2010,33(4):401-408
This study examined whether the quality of caregiver behavior in child care centers contributes to infant cognitive development at 9 months of age. Sixty-four infants (34 boys) were observed with their primary caregivers in child care centers at 3, 6, and 9 months of age. Caregiver behavior was rated for sensitivity and for stimulation of infant development during one-to-one caregiving interactions. Infant cognitive development was assessed using the Bayley Scales of Infant Development-II (Mental Development Index). Higher levels of developmental stimulation in the centers predicted higher levels of infant cognitive development at 9 months, beyond infant cognitive development at 3 months (just before entering child care), parental education, and maternal sensitivity. The results suggest that even small increases in developmental stimulation provided in child care centers in the first year of life may foster infants’ cognitive development. 相似文献
167.
168.
Neuropsychological Sequelae of Subthalamic Nucleus Deep Brain Stimulation in Parkinson's Disease: A Critical Review 总被引:6,自引:0,他引:6
Neuropsychologists are increasingly involved in surgical candidacy evaluations and postoperative neurobehavioral assessments of patients with movement disorders, most notably those with disease (PD). We review here the initial studies regarding neuropsychological outcomes of deep brain stimulation (DBS) within the subthalamic nucleus (STN) for treatment of PD. Overall, these initial investigations provide preliminary support for the cognitive and neurobehavioral safety of STN DBS. Improvements in self-reported symptoms of depression and diminished verbal fluency were the most common findings, whereas changes in global cognitive abilities, memory, attention, and frontal/executive functions were inconsistent and most often described as nominal and/or transient. The generalizability of this literature is hindered by several methodological limitations, including small samples and the absence of appropriate control participants. The clinical and theoretical implications of these initial studies are highlighted and recommendations are offered to guide future research. 相似文献
169.
George A. Ulett Danny Wedding 《Journal of clinical psychology in medical settings》2003,10(2):129-131
Recent studies have demonstrated an alternative to drug treatment for patients presenting with anxiety disorders. This new technique involves electrical stimulation of the peripheral nervous system to induce chemical changes in the brain that can support and promote healing. This method was developed in part from studies of ancient Chinese acupuncture, but it is noninvasive and does not require needles, and it does not depend on prescientific rituals or metaphysical theories. Endorphins, natural neuropeptides active in basal brain structures, act upon anxiolytic receptors. Solid evidence from fMRI and neurochemical studies show that a simple office procedure involving electrical stimulation can stimulate the expression of endorphins in the brain. Patients have demonstrated symptom relief from this simple adjunctive treatment with a concomitant reduction in dependency on psychotropic medications. 相似文献
170.
This paper highlights the neuropsychological sequelae of posteroventral pallidotomy (PVP) and deep brain stimulation (DBS) of the subthalamic nucleus (STN) and the internal segment of the globus pallidus (GPi) at 3/6 months postoperatively. Results are based on our extensive experience with PVP and our preliminary observations with DBS. Patients with borderline cognitive or psychiatric functioning risk postoperative decompensation. Nonlateralizing attentional and hemisphere-specific impairments of frontostriatal cognitive functions followed unilateral PVP. "Frontal" behavioral dyscontrol was observed in approximately 25% of patients. Three cases of staged bilateral PVP suggest that premorbid factors may predict outcome, although lesion size and location are also critical. Older patients are at risk for significant cognitive and behavioral decline after bilateral STN DBS, while GPi DBS may be safer. 相似文献