INTERSPERSED REQUESTS: A NONAVERSIVE PROCEDURE FOR REDUCING AGGRESSION AND SELF-INJURY DURING INSTRUCTION

Interspersed requests are simple commands, with a high likelihood of being followed correctly, that are interspersed among instructional trials to increase the probability that a learner will attempt to perform new or difficult tasks without engaging in aggression or self-injurious behavior. This report presents two assessments of the effect of interspersed requests on aggression and self-injury during instruction. The participants were individuals with severe mental retardation who used aggression and self-injury to avoid difficult instructional situations. Results from both studies indicate that interspersed requests were effective at increasing the responsiveness of the learners to instructions and reducing levels of aggression and self-injury.     

USING TIME DELAY TO PROMOTE SPONTANEOUS SPEECH IN AN AUTISTIC CHILD

One of the frequently observed deficits in autistic children is their lack of spontaneous speech. We used a multiple baseline across behaviors to investigate the effectiveness of a time delay procedure for inducing spontaneous speech in a 10-year-old male autistic child during play. We first taught the child to imitate the experimenter's verbal prompts that described the child's motor response. Once the child reached criteria on imitation, we implemented baseline wherein an immediate verbal prompt for speech was provided after each of the child's motor responses. Intervention consisted of a gradual delay in the presentation of the verbal prompts. The time delay effectively increased the child's spontaneous speech on trained items; some generalization to untrained items also occurred, but only within the same behavioral class of car play. Generalization was also observed across settings. Spontaneous speech remained at high levels during the 4-month maintenance for the behavior of car play but decreased for a second behavior. Decreases in the child's response latencies suggest that spontaneous speech may be an anticipatory verbal response.     

TRAINING MILDLY HANDICAPPED PEERS TO FACILITATE CHANGES IN THE SOCIAL INTERACTION SKILLS OF AUTISTIC CHILDREN

We evaluated the effects of a peer-training strategy, consisting of direct prompting and modeling, on the occurrence and duration of interactions between autistic students and nonautistic peer-trainers. Data were obtained in both training and generalization settings. The results of a multiple-baseline design across students demonstrated that: (a) the direct prompting procedure produced immediate and substantial increases in the occurrences and durations of positive social interactions between the peer-trainers and autistic students; (b) these increases were maintained across time at levels above baseline during subsequent free-play probes; (c) these findings were judged by teachers to be socially valid; (d) untrained peers increased their interactions with the autistic students in three of the four groups; (e) generalization of behavior change across settings occurred only after specific programming; and (f) interactions between untrained peers and peer-trainers decreased following training. Variables that may account for the results and the implications of these findings for peer-mediated interventions are discussed.     

ACQUISITION OF SIGN LANGUAGE BY AUTISTIC CHILDREN. I: EXPRESSIVE LABELLING

There has been growing interest in teaching sign language to autistic children who have failed to develop speech. However, controlled experimentation in this area is nonexistent. In the present study, four nonverbal autistic children were taught expressive sign labels for common objects, using a training procedure that consisted of prompting, fading, and stimulus rotation. The efficacy of the procedure was demonstrated in a multiple-baseline design across objects. The results were reliable, replicable across children, and generalizable across therapists. A stimulus control analysis demonstrated that, for three of the children, correct signing was controlled solely by the visual cues associated with the presentation of a given object and was independent of the auditory cues related to the same object. These latter results are discussed with respect to the known perceptual and linguistic deficits of autistic children.     

GENERALIZED IMITATION AND RESPONSE-CLASS FORMATION IN CHILDREN WITH AUTISM

An experimental analysis of imitation was conducted to examine the influence of response topography on generalization of imitation across three response types. Four children with autism were presented with both reinforced training trials and nonreinforced probe trials of models from vocal, toy-play, and pantomime response types. The probe trials were used to examine generalization within each response type. A multiple baseline design was used to analyze percentage of matching and nonmatching responses to models across response types. This study, the first to analyze imitative response classes in children with autism, showed that imitation generalized from reinforced training models to nonreinforced probe models within a response type, but it did not generalize across response types. Thus, functional response classes determined by topographical boundaries were exhibited within generalized imitation.     

自闭症儿童依恋研究述评

摘要　　研究者曾一度认为自闭症儿童无法建立起依恋关系。本文系统回顾了自闭症儿童依恋研究的最新进展,将自闭症儿童是否存在依恋行为（尤其是安全型依恋行为）、依恋发展解释理论、研究方法、类型分布以及影响因素等问题进行了详细梳理,并结合研究分析,提出有关自闭症儿童依恋研究的几点启示,以供参考。     

Social and attention‐to‐detail subclusters of autistic traits differentially predict looking at eyes and face identity recognition ability

This study distinguished between different subclusters of autistic traits in the general population and examined the relationships between these subclusters, looking at the eyes of faces, and the ability to recognize facial identity. Using the Autism Spectrum Quotient (AQ) measure in a university‐recruited sample, we separate the social aspects of autistic traits (i.e., those related to communication and social interaction; AQ‐Social) from the non‐social aspects, particularly attention‐to‐detail (AQ‐Attention). We provide the first evidence that these social and non‐social aspects are associated differentially with looking at eyes: While AQ‐Social showed the commonly assumed tendency towards reduced looking at eyes, AQ‐Attention was associated with increased looking at eyes. We also report that higher attention‐to‐detail (AQ‐Attention) was then indirectly related to improved face recognition, mediated by increased number of fixations to the eyes during face learning. Higher levels of socially relevant autistic traits (AQ‐Social) trended in the opposite direction towards being related to poorer face recognition (significantly so in females on the Cambridge Face Memory Test). There was no evidence of any mediated relationship between AQ‐Social and face recognition via reduced looking at the eyes. These different effects of AQ‐Attention and AQ‐Social suggest face‐processing studies in Autism Spectrum Disorder might similarly benefit from considering symptom subclusters. Additionally, concerning mechanisms of face recognition, our results support the view that more looking at eyes predicts better face memory.     

Home,homelessness and nowhere-ness in early infancy

The construction of a sense of home in early infancy is a complex achievement. It is intertwined throughout life with the child’s pursuit of a safe physio-mental coverage. This process will be described as an interaction between: (a) a safe dwelling in the body-as-mother (constitution); (b) the internalisation of the mother-as-me (internal object space) and (c) establishing Oedipal triangular space which is responsible for the capacity to move between narcissism-as-a-home and the world-as-a-home. The construction of a home as an interplay between these elements is accompanied by distinct anxieties and unconscious phantasies. Disruptions in this early process, due to deficit, internal object relations or environmental factors, might lead to severe pathologies, mindlessness, hatred, violence and murderousness. A distinction will be made between these mental states of being-at-home, homelessness and nowhere-ness based on the corresponding levels of early development and typical anxieties. Home and homelessness are seen as more developed states of object relating accompanied by some capacity for feelings of loss, mourning and longing. Nowhere-ness, however, stems from early states of anxieties-of-being which are characterised by confusion between self and object, by nameless grief, nameless dread and devastation. The varieties of home, homelessness and nowhere-ness will be discussed with the help of clinical material taken from an analysis of a refugee child on the autistic spectrum and of his father. The role of psychoanalysis and of the psychoanalyst in promoting the creation of an internal home will be described with reference to technique.     

Sex-specific variation in facial masculinity/femininity associated with autistic traits in the general population

Reports linking prenatal testosterone exposure to autistic traits and to a masculinized face structure have motivated research investigating whether autism is associated with facial masculinization. This association has been reported with greater consistency for females than for males, in studies comparing groups with high and low levels of autistic traits. In the present study, we conducted two experiments to examine facial masculinity/femininity in 151 neurotypical adults selected for either low, mid-range, or high levels of autistic traits. In the first experiment, their three-dimensional facial photographs were subjectively rated by 41 raters for masculinity/femininity and were objectively analysed. In the second experiment, we generated 6-face composite images, which were rated by another 36 raters. Across both experiments, findings were consistent for ratings of photographs and composite images. For females, a linear relationship was observed where femininity ratings decreased as a function of higher levels of autistic traits. For males, we found a U-shaped function where males with mid-range levels of traits were rated lowest on masculinity. Objective facial analyses revealed that higher levels of autistic traits were associated with less feminine facial structures in females and less masculine structures in males. These results suggest sex-specific relationships between autistic traits and facial masculinity/femininity.     

消化性溃疡发病机理和治疗新理念

消化性溃疡的发病机理十分复杂,自从发现幽门螺杆菌(Helicobacterpylori,下称Hp)以来,人们对Hp发病机理的认识和治疗策略上都发生了根本性变化,为了阐明消化性溃疡的发病机理和治疗新理念,本文从以下几个问题进行讨论:(1)"溃疡愈合"和"溃疡治愈"与溃疡愈合质量关系;(2)Hp发现是消化性溃疡病因学和治疗学上的一场革命,根除Hp才能降低或预防溃疡复发;(3)保护胃及十二指肠黏膜屏障是治疗消化性溃疡最基本的手段;(4)消化性溃疡治疗新策略应该是:保护胃黏膜;抑制胃酸;根除Hp。希望对读者在对消化性溃疡发病机理的认识和治疗原则上有所指导。