Learning new names for new objects: cortical effects as measured by magnetoencephalography

We tracked the evolvement of naming-related cortical dynamics with magnetoencephalography when five normal adults successfully learned names and/or meanings of unfamiliar objects. In all subjects, the learning of new names was associated with pronounced cortical effects. The learning effect was of long latency and emerged as a change of activation in the same cortical network that was active during naming of familiar items. In four out of five subjects, the cortical learning effect occurred in the inferior parietal lobe. In three of these subjects, the cortical effect was left-sided. These results suggest that the inferior parietal lobe plays an important role in the acquisition of novel words, presumably as a part of working memory systems.     

时间记忆层次网络模型的实验检验

实验采用分类性实验材料,使被试在对词单项目加工时形成较清晰的群集,进而形成时间组块,目的在于对时间记忆层次网络进行直接检验。其中时序判断用反时间时和正确率两种反应指标,时距估计用再现和口头估计两种方法。结果发现,时间信息记忆既存在层次网络的特征,又存在线性结构的特征。     

Liberal bias mediates emotion recognition deficits in frontal traumatic brain injury

It is well-known that patients having sustained frontal-lobe traumatic brain injury (TBI) are severely impaired on tests of emotion recognition. Indeed, these patients have significant difficulty recognizing facial expressions of emotion, and such deficits are often associated with decreased social functioning and poor quality of life. As of yet, no studies have examined the response patterns which underlie facial emotion recognition impairment in TBI and which may lend clarity to the interpretation of deficits. Therefore, the present study aimed to characterize response patterns in facial emotion recognition in 14 patients with frontal TBI compared to 22 matched control subjects, using a task which required participants to rate the intensity of each emotion (happiness, sadness, anger, disgust, surprise and fear) of a series of photographs of emotional and neutral faces. Results first confirmed the presence of facial emotion recognition impairment in TBI, and further revealed that patients displayed a liberal bias when rating facial expressions, leading them to associate intense ratings of incorrect emotional labels to sad, disgusted, surprised and fearful facial expressions. These findings are generally in line with prior studies which also report important facial affect recognition deficits in TBI patients, particularly for negative emotions.     

孤独症谱系障碍者的生物运动探测障碍：基于行为与神经的证据

关于孤独症谱系障碍个体探测生物运动的能力是否受损,已有行为研究尚存分歧。导致分歧的原因可能是实验刺激、实验任务和测量指标存在差异。然而,神经研究却一致证实其潜在的神经机制存在异常。领域特殊性观点认为该障碍可能是基于后侧颞上沟功能异常的社会性功能障碍,也可能是基于镜像神经元功能异常的社会性功能障碍;而领域一般性观点认为该障碍可能是基于背侧视觉流功能异常的视运动知觉障碍,也可能基于脑功能联结异常的弱中央统合障碍。据此,本文将从研究范式、行为表现及潜在机制三个方面梳理相关研究,以期为后续研究提供新方向。     

判断框架对时序知觉位置启动效应的影响

研究采用包含两种判断框架（判断刺激出现的先后次序）的时序判断任务探讨了决策偏向对时序知觉位置启动效应的影响。实验结果表明,时序知觉中存在着位置启动效应,而且在两个靶刺激出现时间间隔不同时,被试在“哪个靶刺激先出现”和“哪个靶刺激后出现”两种判断框架下的正确率存在显著差异,但在两个靶刺激同时出现时并没有出现显著的判断框架效应。因此,本研究推测时序知觉位置启动效应的作用机制不仅包括知觉增强加工过程,而且也与认知决策有关,这为反应偏向理论提供了新的支持证据。     

左右半球在语篇理解中的协同作用

通过2例一侧颞叶损伤患者研究了一侧颞叶损伤及两侧半球的协同作用对语篇理解的影响,并探讨了发生此种影响的可能机制。结果表明一侧颞叶的损伤将导致患者语篇水平的理解障碍及语言推理能力的下降;提示语篇理解需双侧半球的协同作用,而推理能力下降可能是引发语篇理解障碍的原因之一。     

Individual differences in vulnerability to subjective time distortion1

Time duration is perceived to be longer when accompanied by dynamic sensory stimulation than when accompanied by static stimulation. This distortion of time perception is thought to be due to the acceleration of an internal pacemaker that has been assumed to be the main component of temporal judgments. In order to investigate whether the function of the internal pacemaker is modality dependent or independent, we examined the correlation of visual flicker and auditory flutter effects on a temporal production task. While seeing a 10‐Hz visual flicker or hearing a 10‐Hz auditory flutter, participants estimated a duration of 2500 ms as accurately as possible by pressing a button. The results showed a significant within‐individual correlation between the time distortion due to visual flicker and that due to auditory flutter. Additionally, we found that time distortion due to auditory flutter tended to be larger in female participants than in male participants. These results suggest that the mechanisms underlying subjective time dilation are similar between vision and audition within individuals, but that they vary across individuals.     

The interaction of temporal generalization gradients predicts the context effect

In a temporal double bisection task, animals learn two discriminations. In the presence of Red and Green keys, responses to Red are reinforced after 1-s samples and responses to Green are reinforced after 4-s samples; in the presence of Blue and Yellow keys, responses to Blue are reinforced after 4-s samples and responses to Yellow are reinforced after 16-s samples. Subsequently, given a choice between Green and Blue, the probability of choosing Green increases with the sample duration-the context effect. In the present study we asked whether this effect could be predicted from the stimulus generalization gradients induced by the two basic discriminations. Six pigeons learned to peck Green following 4-s samples (S(+)) but not following 1-s samples (S(-)) and to peck Red following 4-s samples (S(+)) but not following 16-s samples (S(-)). Temporal generalization gradients for Green and Red were then obtained. Finally, the pigeons were given a choice between Green and Red following sample durations ranging from 1 to 16 s. Results showed that a) the two generalization gradients had the minimum at the S(-) duration, an intermediate value between the S(-) and the S(+) durations, and the maximum at the S(+) as well as more extreme durations; b) on choice trials, preference for Green over Red increased with sample duration, the context effect; and c) the two generalization gradients predicted the average context effect well. The Learning-to-Time model accounts for the major trends in the data.     

Dopamine regulation of human speech and bird song: a critical review

To understand the neural basis of human speech control, extensive research has been done using a variety of methodologies in a range of experimental models. Nevertheless, several critical questions about learned vocal motor control still remain open. One of them is the mechanism(s) by which neurotransmitters, such as dopamine, modulate speech and song production. In this review, we bring together the two fields of investigations of dopamine action on voice control in humans and songbirds, who share similar behavioral and neural mechanisms for speech and song production. While human studies investigating the role of dopamine in speech control are limited to reports in neurological patients, research on dopaminergic modulation of bird song control has recently expanded our views on how this system might be organized. We discuss the parallels between bird song and human speech from the perspective of dopaminergic control as well as outline important differences between these species.