Developmental dissociation of visual dorsal stream parvo and magnocellular representations and the functional impact of negative retinotopic BOLD responses

Localized neurodevelopmental defects provide an opportunity to study structure–function correlations in the human nervous system. This unique multimodal case report of epileptogenic dysplasia in the visual cortex allowed exploring visual function across distinct pathways in retinotopic regions and the dorsal stream, in relation to fMRI retinotopic mapping and spike triggered BOLD responses.     

Development of rule-based eye-hand-decoupling in children and adolescents

In the present study, we characterize how the ability to decouple guiding visual information from a motor action emerges during childhood and adolescence. Sixty-two participants (age range 8–15 yrs.) completed two eye-hand coordination tasks. In a direct interaction task, vision and motor action were in alignment, and participants slid their finger along a vertical touch screen to move a cursor from a central target to one of four peripheral targets. In an eye-hand-decoupled task, eye and hand movements were made in different planes and cursor feedback was 180° reversed. We analyzed whether movement planning, timing and trajectory variables differed across age in both task conditions. There were no significant relationships between age and any movement planning, timing, or execution variables in the direct interaction task. In contrast, in the eye-hand-decoupled task, we found a relationship between age and several movement planning and timing variables. In adolescents (13–15 yrs.), movement planning and timing was significantly shorter than that of young children (8–10 yrs.). Eye-hand-decoupled maturation emerged mainly during late childhood (11–12 yrs.). Notably, we detected performance differences between young children and adolescents exclusively during the eye-hand decoupling task which required the integration of rule-based cognitive information into the motor action. Differences were not observed during the direct interaction task. Our results quantify an important milestone for eye-hand-decoupling development in late childhood, leading to improved rule-based motor performance in early adolescence. This eye-hand-decoupling development may be due to frontal lobe development linked to rule-based behavior and the strengthening of fronto-parietal networks.     

Calibration and Alignment are Separable: Evidence From Prism Adaptation

In 2 prism adaptation experiments, the authors investigated the effects of limb starting position visibility (visible or not visible) and visual feedback availability (early or late in target pointing movements). Thirty-two students participated in Experiment 1 and 24 students participated in Experiment 2. Independent of visual feedback availability, constant error was larger and variable error was smaller for target pointing when limb starting position was visible during prism exposure. Independent of limb starting position visibility, aftereffects of prism exposure were determined by visual feedback availability. Those results support the hypothesis that calibration is determined by limb starting position visibility, whereas alignment is determined separately by visual feedback availability.     

Task preparation in macaque monkeys (<Emphasis Type="Italic">Macaca mulatta</Emphasis>)

We investigated whether macaque monkeys possess the ability to prepare abstract tasks in advance. We trained two monkeys to use different stimulus-response (S-R) mappings. On each trial, monkeys were first informed with a visual cue which of two S-R mapping to use. Following a delay, a visual target was presented to which they would respond with a left or right button-press. We manipulated delay time between cue and target and found that performance was faster and more accurate with longer delays, suggesting that monkeys used the delay time to prepare each task in advance. Electronic Publication     

抑制控制在类比映射发展中的作用:认知负荷的影响

本研究采用负启动范式,设置不同的认知负荷任务,探究抑制控制在儿童和成人类比映射中的作用。实验一中,31名7岁儿童、33名10岁儿童和34名成人完成高认知负荷的相对大小类比映射的负启动任务。结果表明,所有群体均出现负启动效应,且负启动效应随年龄增长而减小。实验二中,30名7岁儿童、30名10岁儿童和32名成人完成低认知负荷的相对大小类比映射的负启动任务。结果表明,所有群体均出现负启动效应,但负启动效应无显著年龄差异。本研究的结果揭示了抑制控制和认知负荷在类比映射发展中的重要作用。     

THE WHOLE BRAIN AS THE BASIS OR THE ANALOGICAL EXPRESSION OF GOD

Abstract. As human beings we inevitably try to explain our experience. In philosophical language, we deal with transcendent assertions and aspirations. The issue, then, is: how can we talk about what matters, given the structures inherent in language and basic to the way we are made? Instead of the philosophical category of Being, I advance a case for giving the human brain privileged status as an analogical expression of God, the symbol-concept of what matters most, and then suggest the illumination which can come with using that analogical expression, especially as that analogy connects us with the environment at the limbic level and constructs our world at the cerebral level.     

梨状皮层或苍白球损毁对大鼠空间认知能力的影响

在Ｍｏｒｒｉｓ迷宫中,梨状皮层或苍白球损毁大鼠的空间认知作业成绩较显著低于控制组,搜索目标以趋向式策略为主,与正常大鼠搜索策略的差异提示：①梨状皮层和苍白球参与了空间认知加工;②在图认知系统中梨状皮层和苍白球居辅助层次。     

Conceptual Integration of Arithmetic Operations With Real‐World Knowledge: Evidence From Event‐Related Potentials

Research on language processing has shown that the disruption of conceptual integration gives rise to specific patterns of event‐related brain potentials (ERPs)—N400 and P600 effects. Here, we report similar ERP effects when adults performed cross‐domain conceptual integration of analogous semantic and mathematical relations. In a problem‐solving task, when participants generated labeled answers to semantically aligned and misaligned arithmetic problems (e.g., 6 roses + 2 tulips  = ? vs. 6 roses + 2 vases  = ?), the second object label in misaligned problems yielded an N400 effect for addition (but not division) problems. In a verification task, when participants judged arithmetically correct but semantically misaligned problem sentences to be “unacceptable,” the second object label in misaligned sentences elicited a P600 effect. Thus, depending on task constraints, misaligned problems can show either of two ERP signatures of conceptual disruption. These results show that well‐educated adults can integrate mathematical and semantic relations on the rapid timescale of within‐domain ERP effects by a process akin to analogical mapping.     

内隐学习的主观测量标准

近40年来,验证知识的内隐性一直是内隐学习研究的焦点。传统三大范式常以自由言语报告或是迫选测验作为验证知识内隐性的外显指标,然而各种迹象表明,言语报告和迫选测验存在一定的局限性。由此,Dienes等人提出了内隐学习的主观测量。文章将从言语报告和追选测验的局限性着手,阐述主观测量诞生的必要性及其在衡量知识意识性上的效度。