循证医学与靶向治疗——心血管病治疗前沿领域的辩证思考

循证医学与靶向治疗均透露着哲学的智慧,体现着哲学思想。循证医学符合现代医学科学性、先进性、系统性要求,集中体现了科学的医学认识论和实践观：靶向冶疗理论认为疾病的产生有具体的原因,最好的治疗是从病因学的角度,从基因蛋白的水平找准靶点进行治疗,靶向治疗理论贯穿了唯物主义可知论的观点。在心血管病治疗的临床实践中我们应当将循证医学与靶向治疗两者有机地统一,通过优势互补,取长补短,弥补两种方法各自的不足,发扬其长处,共同促进心血管病治疗学的发展。     

用科学的证据和科学的管理指引心血管疾病的防治

心血管疾病的防治不仅仅是心血管医生的问题,还是一个在循证医学引领下的一个全民生活方式改变的问题,也需要多学科相关专业的联盟,涉及心血管疾病治疗规范的形成与普及,对于疾病发生、发展各个阶段的科学管理更是冠心病的防治效果的重要保障。本文针对心血管病冠心病预防的具体实施,从几方面打开了一个全新的视野。     

简论惠栋标帜"汉学"的易学特色

论文分"崇尚汉易家法"、"融通汉易师法"、"批评图书易学"种"学术价值与思想意义"四部分,论述了乾嘉著名易学大师惠栋的易学研究。论文指出:一、惠栋研究《周易》,重视汉易的家法,融通汉易师法,提倡复归汉代的象数易学,体现了他对传统易学的继承与超越;二、作为经学大师,惠栋企图借鉴汉代象数易学理论来指导易学研究,既是他诠释易学当代价值的认真尝试,也是他以独特的方式延续了象数易学的生命;三、惠栋梳理汉易各家源流、勾勒其象数学特点,祛除宋儒图书易学中的臆说的流弊,成为清代易学研究的一个成功典范,具有转变当时学风与确立十八世纪经学研究方向的意义。     

类别不确定下的特征推理是基于类别还是基于特征联结

共有3个实验探讨归类不确定情况下的特征推理是基于类别进行还是基于特征联结进行。实验1在中文条件下重复了Verde等人2005的实验,得出了与之相符的结果,这个结果用基于类别的理性模型的设想或者是用基于特征联结的设想都可以解释。实验2考察被试在靶类别的类别特征频次并且特征结合出现频次高低不同的条件下特征推理的情况,实验2的结果表明,高集中与低集中两种条件下特征推理没有显著差异,不符合特征推理是基于类别进行的设想,而与特征推理是基于特征联结进行的设想吻合。实验3进一步考察被试在特征结合出现的总频次并且靶类别中特征结合出现的总频次高低不同的条件下特征推理的情况,结果表明,在高结合条件下进行特征推理要优于在低结合条件,支持了在归类不确定情况下的特征推理是基于特征联结进行的设想。据此可以认为,人们的特征推理是基于特征之间联结的频次进行,而不是基于类别进行     

Beliefs About Psychological Services (BAPS): development and psychometric properties

A scale to measure attitudes towards seeking psychological help was developed (Beliefs About Psychological Services [BAPS]) and evaluated. This scale was based on items gathered from students, colleagues, and the authors when asked about common positive and negative attitudes toward psychologists and their services. Items were also based on the Fischer and Turner (1970 Fischer, EH and Turner, JLeB. 1970. Orientations to seeking professional help: Development and research utility of an attitude scale. Journal of Consulting and Clinical Psychology, 35: 79–90. [Crossref], [PubMed], [Web of Science ®] [Google Scholar]) Attitudes Toward Seeking Professional Psychological Services (ATSPPH) measure. Three studies are reported describing the construction and evaluation of the psychometric properties of the BAPS. The BAPS is an 18-item measure consisting of three subscales: Intent, Stigma Tolerance, and Expertness. Support was found for the reliability and validity of the measure.     

Visual attention capacity: a review of TVA-based patient studies

Psychophysical studies have identified two distinct limitations of visual attention capacity: processing speed and apprehension span. Using a simple test, these cognitive factors can be analyzed by Bundesen's Theory of Visual Attention (TVA). The method has strong specificity and sensitivity, and measurements are highly reliable. As the method is theoretically founded, it also has high validity. TVA-based assessment has recently been used to investigate a broad range of neuropsychological and neurological conditions. We present the method, including the experimental paradigm and practical guidelines to patient testing, and review existing TVA-based patient studies organized by lesion anatomy. Lesions in three anatomical regions affect visual capacity: The parietal lobes, frontal cortex and basal ganglia, and extrastriate cortex. Visual capacity thus depends on large, bilaterally distributed anatomical networks that include several regions outside the visual system. The two visual capacity parameters are functionally separable, but seem to rely on largely overlapping brain areas.     

对归纳推理贝叶斯模型的检验

作者用实验比较检验特征归纳的贝叶斯模型、关联相似性模型、基于特征的归纳推理模型和相似性覆盖模型这四种模型。以大学生为被试的实验结果表明：1）在强关联强度一致时,被试的归纳推理基本符合贝叶斯模型和关联相似性模型的预测,在弱关联强度一致时,不符合这四种模型预测;2）在关联强度不一致时,关联强度效应不符合贝叶斯模型的预测;3）在关联强度一致时,贝叶斯模型和关联相似性模型的预测结果是一致的,不能区分两个模型。实验结果较多地支持贝叶斯模型和关联相似性模型。     

CONSTRUCTING AND DERIVING RECIPROCAL TRIGONOMETRIC RELATIONS: A FUNCTIONAL ANALYTIC APPROACH

Participants were pretrained and tested on mutually entailed trigonometric relations and combinatorially entailed relations as they pertained to positive and negative forms of sine, cosine, secant, and cosecant. Experiment 1 focused on training and testing transformations of these mathematical functions in terms of amplitude and frequency followed by tests of novel relations. Experiment 2 addressed training in accordance with frames of coordination (same as) and frames of opposition (reciprocal of) followed by more tests of novel relations. All assessments of derived and novel formula‐to‐graph relations, including reciprocal functions with diversified amplitude and frequency transformations, indicated that all 4 participants demonstrated substantial improvement in their ability to identify increasingly complex trigonometric formula‐to‐graph relations pertaining to same as and reciprocal of to establish mathematically complex repertoires.     

School‐based integrated and segregated interventions to reduce aggression

The goal of the study was to assess two types of school‐based interventions—a class intervention (integrated) and a small group counseling (segregated) intervention for highly aggressive children—and to determine which is more efficacious in reducing individual and classroom aggression, lessening internalizing and externalizing behavior, and increasing positive classroom relationships. The study, conducted in Israel, included 904 children from 13 schools. In each school, one age level was selected and divided randomly into three experimental conditions: psychoeducational class intervention, small group counseling, and control. In all classrooms, the highly aggressive children were identified a priori (n=166). Analyses were conducted separately for the aggressive children and their nonaggressive classmates, in a nested procedure (mixed models). Results showed similar positive outcomes on all variables in both treatment groups, and higher compared with the control group. The discussion focuses on the strengths of each type of intervention. Aggr. Behav. 35:342–356, 2009. © 2009 Wiley‐Liss, Inc.     

A qualitative exploration into how the use of prayer in counselling and psychotherapy might be ethically problematic

Aim: This research article contributes to the debate on the value and limitation of the use of spiritual strategies, like prayer, in counselling (Foskett & Lynch, 2001) by disseminating the insights that were gained from a qualitative study of mainstream counsellors whose work includes prayer. Method: Participants were 19 British Association for Counselling and Psychotherapy (BACP)‐accredited and Churches Ministerial Counselling Service (CMCS)‐approved counsellors who use prayer in their practice. They were interviewed, and the data were analysed using Interpretative Phenomenological Analysis. Results: The data reveal that counsellors who use prayer are aware that ethical problems may be encountered: if prayer changes the way that the counsellor is perceived; when using prayer with issues of psychopathology; if the counsellor uses prayer to impose faith on a client; when being professionally held to account; if prayer is used for avoidance or as a defence; if prayer is used to enhance the counsellor's power; if prayer is not part of the client's agenda; if prayer is used routinely; if prayer cannot be challenged; if there is a cultural pressure to pray; and if the prayer method is not matched to the client – but that their concern over potential ethical issues is not of sufficient strength to override their therapeutic use of prayer if facilitated with due care.