蒙汉族大学生父母教养方式、成人依恋与心理困扰的关系研究

通过整群抽样方法抽取了576名大学生,对其施测父母养育方式量表、亲密关系体验量表和心理困扰量表,运用结构方程模型技术,分别考察了父母养育方式的蒙汉族差异以及成人依恋模式在父母养育方式和心理困扰间的中介作用。结果表明:(1) 蒙古族父母对孩子的关爱程度和给孩子的自主性要显著高于汉族;(2) 汉族的成人依恋模式在父母过度保护与抑郁-焦虑-压力之间起着部分中介作用,而蒙古族成人依恋的中介作用不明显,但母亲的冷漠拒绝和过度保护会导致个体依恋回避和依恋焦虑,父亲的冷漠拒绝和过度保护会影响个体的抑郁和焦虑,母亲的过度保护和父亲的冷漠拒绝会影响个体的压力。     

Executive Functioning Among College Students With and Without History of Childhood Maltreatment

This study utilized performance-based and self-report measures to examine differences in executive functions in college students with and without histories of childhood maltreatment. On the performance-based measures of executive function, all scores fell within the normal range for age. However, participants in the childhood maltreatment group reported more problems with metacognition than those without history of maltreatment. Severity of childhood maltreatment was associated with poorer cognitive inhibition/switching and phonetic fluency. Although significant group differences were found on a laboratory-based task of executive function, performance across the other tasks was generally similar. However, those with a history of maltreatment reported more problems with metacognition, suggesting a potential avenue for brief interventions focused on improving metacognitive skills important for success in the college environment. Implications and suggestions for future research are discussed.     

非雄激素依赖型前列腺癌与肿瘤干细胞——浅析辩证思维之于临床医学的方法论作用

在前列腺癌的治疗中,由于癌细胞的不断“升级”使得治疗屡屡受挫。近来提出的肿瘤干细胞理论认为:肿瘤是一种干细胞疾病,只有消灭了“种子”,才能克服癌症。从自然辩证法的角度,结合肿瘤干细胞理论对前列腺癌的诊疗加以分析,解释非雄激素依赖型前列腺癌的发病机制,以一种新的思维指导临床治疗。     

植入前组织配型孕育“救星同胞”的伦理思考

应用植入前遗传学诊断技术在胚胎植入母体子宫前,对人类白细胞组织相容性抗原配型检测,选择与现存患儿相同HLA配型的胚胎进行受孕,孕育一个组织配型相同的脐带血干细胞供者。在某种意义上说,该项技术的应用是创造人来获得移植组织,由此引发系列伦理争议。讨论孕育"救星同胞"这一医学实践内在需要的伦理规范。     

Adolescent psychopathy features: 6-year temporal stability and the prediction of externalizing symptoms during the transition to adulthood

This study investigated the 6-year stability and predictive validity of adolescent psychopathy features during the transition to young adulthood. It represents one of the longest outcome studies of youth psychopathy to date, and therefore addresses a primary criticism of the research area (i.e., lack of demonstrated associations between child and adult psychopathy features). Recruited participants were 475 males enrolled in the Minnesota Twin and Family Study who had completed a research-based measure of psychopathy features consisting of separate emotional detachment (or affective) and antisocial tendencies (or behavioral) subscales. These psychopathy features and various externalizing symptoms (i.e., conduct problems, impulsivity, and substance use disorder) were assessed through rating scales and structured diagnostic interview at an intake assessment (ages 16-18) and 6-year follow-up. Consistent with prediction, adolescent psychopathy features displayed moderate stability across the transition from adolescence to adulthood [intraclass correlation coefficients (ICCs) = 0.40-0.41]. The antisocial tendencies subscale was uniquely related to most externalizing symptoms both in adolescence and in adulthood, whereas the emotional detachment subscale showed appropriate discriminant validity in its lack of association with externalizing symptoms. These findings suggest that psychopathy features are relatively stable from adolescence to adulthood and provide possible insights into the development and maintenance of externalizing difficulties during the adult transition.     

Spatial limits on referred touch to an alien limb may reflect boundaries of visuo-tactile peripersonal space surrounding the hand

In this study, the spatial limits of referred touch to a rubber hand were investigated. Participants rated the strength of the perceived illusion when the rubber hand was placed in one of six different spatial positions (at a distance of 17.5-67.5cm horizontal from the participant's own hand). The results revealed a significant nonlinear relationship in the strength of the illusion, with the strongest ratings given when the two hands were closest; decaying significantly after a distance of 30cm. The time taken to elicit the illusion followed a similar trend. These results may reflect the response properties of bimodal visuo-tactile cells encoding peripersonal space around the hand.     

成人依恋、情绪调节与主观幸福感:重新评价和表达抑制的中介作用

通过对1163名大学生被试进行成人依恋关系、情绪调节策略的使用以及主观幸福感的测查,该研究从情绪调节这一新的视角,深入探讨了成人依恋对主观幸福感产生影响的可能机制。结果发现:重新评价策略的使用在依恋安全对主观幸福感影响中具有重要的中介作用;依恋回避直接影响个体的主观幸福感;表达抑制对主观幸福感影响不显著。这些结果表明重新评价策略的使用是成人依恋关系影响个体主观幸福感的一个重要途径。     

Memory influences on hippocampal and striatal neural codes: effects of a shift between task rules

Interactions with neocortical memory systems may facilitate flexible information processing by hippocampus. We sought direct evidence for such memory influences by recording hippocampal neural responses to a change in cognitive strategy. Well-trained rats switched (within a single recording session) between the use of place and response strategies to solve a plus maze task. Maze and extramaze environments were constant throughout testing. Place fields demonstrated (in-field) firing rate and location-based reorganization [Leutgeb, S., Leutgeb, J. K., Barnes, C. A., Moser, E. I., McNaughton, B. L., & Moser, M. B. (2005). Independent codes for spatial and episodic memory in hippocampal neuronal ensembles. Science, 309, 619-623] after a task switch, suggesting that hippocampus encoded each phase of testing as a different context, or episode. The task switch also resulted in qualitative and quantitative changes to discharge that were correlated with an animal's velocity or acceleration of movement. Thus, the effects of a strategy switch extended beyond the spatial domain, and the movement correlates were not passive reflections of the current behavioral state. To determine whether hippocampal neural responses were unique, striatal place and movement-correlated neurons were simultaneously recorded with hippocampal neurons. Striatal place and movement cells exhibited a response profile that was similar, but not identical, to that observed for hippocampus after a strategy switch. Thus, retrieval of a different memory led both neural systems to represent a different context. However, hippocampus may play a special (though not exclusive) role in flexible spatial processing since correlated firing amongst cell pairs was highest when rats successfully switched between two spatial tasks. Correlated firing by striatal cell pairs increased following any strategy switch, supporting the view that striatum codes change in reinforcement contingencies.     

成人依恋的测量：亲密关系经历量表（ECR）中文版

为了促进在中国开展有关成人依恋的研究,对目前国外该领域中广泛采用的“标准”成人依恋量表——“亲密关系经历量表（ECR）”——进行了中文版修订。371名中国大学生接受了测试,并用自尊量表,他人观量表等作为检验效度的依据。其中59人在四周后进行了重测。对其中的231名正处于恋爱中的被试的结果进行了统计分析,包括采用项目反应理论进行项目分析、信效度检验。结果表明,该量表的中文版具有较好的信度（内部一致性、和重测信度）以及效度（构想效度和效标效度）