成人股骨头坏死的治疗进展

股骨头坏死（ONFH）是一种进展性和致残性疾病,保存自身股骨头是临床治疗所追求的最理想目标,早中期的治疗方案主要采用非手术疗法和保髋的姑息性手术,目前为止还没有一种治疗方法能达到理想的治疗效果。近年来,骨髓间充质于细胞（MSCs）移植治疗ONFH是目前研究热点之一,有望成为一种有效的治疗方法,晚期行人工髋关节置换术是唯一的和最佳的选择。因此,早期诊断,采用综合性治疗方案保全自身髋关节是治疗本病的主要方向。     

Age and Emotion in Adulthood

Evidence suggests that positive affect rises from youth through young and then older adulthood, but may decline after one’s mid-70s. Negative affect appears to decrease steadily from early adulthood to older adulthood, but this decline may taper off in the oldest years. The relationship between age and affect in adulthood is further complicated by the effects of moderators, such as extraversion and marital status. Despite these complexities, recent empirical studies and current theory have furthered the understanding of age and affect in adulthood, although important questions remain.     

Continuity of aggression from childhood to early adulthood as a predictor of life outcomes: implications for the adolescent‐limited and life‐course‐persistent models

Using data from the Columbia County Longitudinal Study, a 40‐year longitudinal study following an entire county's population of third‐grade students from age 8 to 48, we examine questions about the long‐term consequences of aggressive and antisocial behavior in childhood, adolescence, and young adulthood. We found moderate levels of continuity of aggression from age 8 to 48 both for males and for females. Contrary to what some have proposed, we found that continuity of aggressiveness is owing to not only the high‐aggressive participants staying high but also owing to the low‐aggressive participants staying low. Compared with life‐course‐persistent low aggressives, we found that life‐course‐persistent high aggressives had consistently poorer outcomes across domains of life success, criminal behavior, and psychosocial functioning at age 48 (e.g., arrests, traffic violations, aggression toward spouse and divorces, depression, health, occupational and educational attainment). In contrast, adolescent‐limited and child‐limited aggressives did not differ from life‐course‐persistent low aggressives on the age 48 outcomes. Finally, the outcomes for late‐onset (early adulthood) aggressives were also problematic in some domains though not as problematic as those for life‐course‐persistent aggressives. Aggr. Behav. 35:136–149, 2009. © 2009 Wiley‐Liss, Inc.     

成人言语输入对儿童早期单词获得影响的个案追踪

追踪观察一名婴儿(6~20个月), 分析其中看护者的言语输入特征及婴儿早期词汇获得的发展变化。主要对成人言语输入中动、名词比例、单词在句中的位置、具体环境等因素及婴儿早期动、名词理解和产生等方面进行探讨。结果显示, 成人言语输入中动词比例显著高于名词, 更多动词位于句首或句尾使得主语和宾语省略; 同时, 这种动词优势的输入特征促进儿童早期动词获得, 使得婴儿早期语言样本中动、名词理解相对比例与成人言语输入一致。这一结果表明, 婴儿词汇发展初期就已经利用言语或社会线索, 同时这种早期词汇组成中较高的动词比例进一步支持“名词优势”理论存在跨语言差异     

BIOTECHNOTHEOLOGY AND DEMYTHOLOGIZATION OF STEM‐CELL RESEARCH

Biotechnology deals not only with new types of therapies for preventing and curing diseases but also with the creation of new technologies for the production of human flesh. Its ultimate aim is to create a new human body, a new person. Biotechnology wears the cloak not only of a new scientific paradigm but also of a kind of messianic religion. To develop new therapies, to destroy illnesses, to transform the human body into a nonmortal one—these are some of the promises it makes. In time, many of these promises will undoubtedly prove to be illusory, but they will nevertheless continue to have a significant impact on the way people think. Through a process that I call biotechnotheological analysis I show that biotechnology could eventually become not only a type of secular religion but even a type of mythic para‐Christian religion, one that incorporates the two most significant processes at work in every mythical religion: the process of mimesis and the ritual of the scapegoat. The essay is an attempt to understand biotechnological achievements, especially in stem‐cell research, in this new biotechnotheological way.     

胰岛细胞再生研究的临床应用前景

胰岛细胞再生是治愈1型糖尿病和胰岛β细胞功能丧失的2型糖尿病的根本途径。体外再生和体内再生两种策略都是通过将干细胞或其他类型体细胞分化或转化为胰岛细胞后发挥胰岛素分泌功能,从而治疗糖尿病。基础研究显示,两者存在着各自的优势和面临的问题。胰岛细胞再生治疗的临床应用前景尚需要进一步加以考证。     

老年人依恋对主观幸福感的影响:孤独感与自尊的中介作用

采用亲密关系经历量表（ECR）、UCLA孤独量表、罗森伯格自尊量表和纽芬兰纪念大学幸福感量表（MUNSH）对311名老年人进行调查,探讨老年人依恋对主观幸福感的影响,以及孤独感和自尊的中介作用。结果发现：（1）孤独感在依恋焦虑对主观幸福感的影响中起部分中介作用,孤独感在依恋回避对主观幸福感的影响中起完全中介作用;自尊在依恋焦虑、依恋回避对主观幸福感的影响中不起中介作用;（2）孤独感、自尊在依恋焦虑、依恋回避对主观幸福感的影响中起链式中介作用。     

视觉预期的类型及神经机制

视觉预期是一种运用视觉信息的部分资源和先行资源对即将发生的事件进行预测的能力。为了人们更加清楚地认识视觉预期的内在加工过程,同时也有助于国内外研究者更为科学深入地探讨这种自上而下的加工,本文主要从婴幼儿和成人运动员两方面来阐述视觉预期的相关研究。首先从婴幼儿对物体相关属性和行为目标的视觉预期两方面探讨了视觉预期的类型,然后论述了成人视觉预期的神经机制。最后,指出今后的研究应加强视觉预期相关技术在临床诊断中的应用,注重环境在视觉预期中的作用,从神经网络角度研究视觉预期的神经基础。     

青年子女的传统孝观念及其与早期父母教养行为的关系

采用孝道认知量表和简式父母教养方式问卷, 调查了479名青年子女的传统孝观念, 探讨在青年独生和非独生子女群体中, 传统孝观念的保持情况, 以及传统孝观念与早期(18岁以前)父母教养行为的关系。结果发现:(1)青年子女的传统孝观念整体上有弱化的趋势;独生子女和非独生子女的孝观念并无显著差异;(2)性别对传统孝观念存在一定影响, 女性尊亲恳亲和奉养祭念的孝观念显著强于男性;(3)父母的教养行为与子女孝观念的强弱有密切关联, 且这种关联因家庭结构的不同而存在差异。     

老年人夫妻依恋稳定性及其与配偶支持的关系

通过追踪研究,考察了老年人夫妻依恋的稳定性及配偶支持情况对夫妻依恋稳定性的影响.共有75名配偶健在的老年人参与了间隔3年的两次调查,第一次参与研究时的年龄范围为60~84岁.老年人夫妻依恋问卷和配偶支持问卷分别用来测量夫妻依恋和经历生活事件时夫妻间的支持情况.结果表明:(1)老年人夫妻依恋安全、依恋焦虑和依恋回避的跨时间稳定性较低;(2)对于依恋的变化,配偶支持是较生活事件发生数量更有效的预测指标,觉知到的配偶支持水平和支持满意度能够显著预测依恋安全、依恋焦虑和依恋回避分数的改变.