Functional recovery of skilled forelimb use in rats obliged to use the impaired limb after grafting of the frontal cortex lesion with homotopic fetal cortex

The long-term effect of transplanting embryonic frontal cortex into a unilateral frontal cortex lesion has been studied in adult rats. Before surgery, activity in an open field, muscular strength of both forelimbs, and performance in a paw-reaching-for-food task were scored in 26 rats. In 21 animals a unilateral cortex lesion was then made in the forelimb motor area of the hemisphere contralateral to the preferred paw in the paw-reaching-for-food task, while the other 5 animals were sham-operated. On retesting, the lesion animals changed the preferred paw. A solid homotopic transplant of embryonic tissue (embryonic day 17) was then placed in the lesion cavity in 11 of the lesion rats. Three months later neither lesion alone nor lesion plus transplantation affected open field behavior and muscular strength, but the lesion permanently affected performance in the paw-reaching-for-food task, as shown by a change of preferred paw and a functional deficit in the paw contralateral to the lesion. Transplantation ameliorated the deficits caused by the lesion, but this was only evident when animals were forced to reach with the paw contralateral to the lesion plus transplant. The behavioral results were independent of the size of the lesion and graft. Connections between graft and host tissue were studied by means of the fluorescent tracer 1,1'-dioctadecyl-3,3,3'3'-tetramethylindocarbocyanine perchlorate (DiI). A dense array of labeled fibers was found in the host cortex adjacent to the transplant. The results suggest that functional recovery depends on grafting but is only evident when the animal is obliged to use the affected limb.     

The ADHD Response-Inhibition Deficit as Measured by the Stop Task: Replication with DSM–IV Combined Type, Extension, and Qualification

Although response inhibition has been proposed as a core element of child attention-deficit hyperactivity disorder (ADHD), the literature is heavily reliant on studies using DSM–III–R diagnostic criteria, older methods of measuring response inhibition, samples of boys, and failing to control thoroughly for comorbid problems—both as diagnoses and as subclinical variation. The present study replicated a deficit in response inhibition in the ADHD combined type (DSM–IV, American Psychiatric Association, 1994) using samples matched on age and sex. The study replicated an effect size of approximately d = .6 in boys with ADHD, and observed an even larger effect size for girls, although the Sex × Group interaction was nonsignificant. Children with ADHD also had problems with response output, shown by variable responding. Excluding comorbid conduct disorder, reading disorder, generalized anxiety disorder, obsessive–compulsive disorder, major depression, and posttraumatic stress disorder from the sample did not alter the results. Correlations indicated that response inhibition was associated with both attentional problems and reading level. Covarying for reading problems did not eliminate the ADHD group effect, but the association of response inhibition with reading clearly requires further examination. Overall, the study supported the role of response inhibition in the DSM–IV ADHD combined type, but with key qualifications as to degree of specificity in reference both to comorbid problems and other executive functions.     

Sequenced neurocognitive and behavioral parent training for the treatment of ADHD in school-age children

The present study examines the potential of sequencing a neurocognitive intervention with behavioral parent training (BPT) to improve executive functions (EFs), psychiatric symptoms, and multiple indices of functional impairment in school-age children aged 7 to 11 years who have been diagnosed with attention-deficit/hyperactivity disorder (ADHD). Specifically, in a randomized controlled trial design, 85 children were assigned to either Cogmed Working Memory Training (CWMT) followed by an empirically supported, manualized BPT intervention, or to a placebo version of CWMT followed by the same BPT intervention. Working memory maintenance (i.e., attention control/short-term memory), working memory processing and manipulation, ADHD and oppositional defiant disorder (ODD) symptoms, impairment in parent–child dynamics, familial impairment, and overall functional compromise were evaluated as outcomes. The results suggest specific effects of the combined CWMT and BPT program on verbal and nonverbal working memory storage and nonverbal working memory processing and manipulation but no incremental benefits in regard to ADHD symptoms, ODD symptoms, and functional outcomes. The present findings do not support the hypothesis regarding the complementary and augmentative benefits of sequenced neurocognitive and BPT interventions for the treatment of ADHD. These results, the study’s limitations, and future directions for research are further discussed.     

How young adults address their parents reflects their perception of parenting

A speaker's use of a title for the listener shows the speaker's deference to the listener. Previous studies suggested that the use of kinship terms in the family also shows deference to the listener. The present study focused on young adults' use of kinship terms for their parents to investigate whether their use of kinship terms reflects their perception of their parenting. The participants were 329 Japanese college students, who answered a questionnaire about their forms of address for their parents, perceived parental emotional accessibility, and perceived parental control. They also reported their satisfaction with their parent–child relationships and the frequency of parent–child communication. The results suggest that young adults who use kinship terms for their parents perceive their parents to be more emotionally accessible and communicate with their parents more than those who do not. Young adults who use kinship terms for their father are also more satisfied with their father–child relationships than those who do not. Young adults' use of kinship terms might signal not only their deference to their parents, but also their acceptance of their parent–child relationships.     

Chinese college students' general and relationship‐specific representations of adult attachment: Variable‐centred and person‐centred analysis

Formerly, researchers often treated adult attachment as a trait‐like construct with consistency across relationship contexts. However, recent studies have shown that people possess multiple relationship‐specific attachment representations, and inter‐correlations among them are only in a small‐to‐medium range. The aim of this study is to test whether these variable‐centred results could be replicated in China and further supplement them with a person‐centred analysis focusing on identifying prototypical patterns of multiple working models across relationships. We administrated measurements of general and four relationship‐specific (mother/father/best friend/romantic partner) working models and indicators of psychological adjustment upon 302 Chinese college students. Results from variable‐centred analysis demonstrated the cross‐relationship variability in working models. Furthermore, global indicators of psychological adjustment were better predicted by general models, while relationship‐specific indicators were better predicted by corresponding relationship‐specific models. These results largely replicate previous Western studies, supporting the existence of multiple attachment representations in China. In person‐centred analysis, a latent profile analysis identified four typical classes of working model profiles: all‐average, all‐secure, romantic‐insecure and peer‐secure. These classes differed not only in the cross‐relationship variability of their working models, but also in their levels of psychological adjustment. These interesting patterns may have theoretical implications and are worthy of further examination.     

A model of communicative perspective-taking for typical and atypical populations of children

Successful communication requires that individuals attend to the perspective of their conversational partners and use this information to modify their behavior accordingly. This paper presents a framework by which to understand children’s communicative perspective-taking skills and, within this framework, outlines three routes by which children’s communicative perspective-taking performance can be disrupted. First, children may have difficulty in communicative contexts due to deficits in mentalizing ability whereby they are unable to appreciate another’s perspective. Second, children may have intact mentalizing abilities but do not have the cognitive skills to support the use of this information when generating communicative behaviors. Third, decreased social exposure may lead to exacerbated deficits in either mentalizing ability or the use of mentalistic information within communicative contexts. Patterns within both typical and atypical populations (i.e., autism, ADHD, and mood disorders) are reviewed.     

The Culture-Embedded Social Problem of Elder Mistreatment: A Review of International Literature on Asian Elders

Elder mistreatment is now recognized as a worldwide social problem occurring in all racial and ethnic groups. The research on elder mistreatment started in the late 1970s and expanded its focus to ethnic elderly groups including Asian elders in the mid-1980s. Many researchers have explored the issues of elder mistreatment in conjunction with Asian elders’ culture and immigration backgrounds. This article reviews the state of the literature on elder mistreatment among Asians living in Asia or abroad to identify future directions of research, prevention, intervention, and policy. This research indicates that prevention, education, and intervention must take into account the cultural backgrounds of Asian elders and their family members. There is clearly a need for greater research into appropriate elder mistreatment prevention and intervention with Asian elders and their family members.