Optimism across cultures: In response to the severe acute respiratory syndrome outbreak

Based on our early research, we predicted that the Chinese may be more optimistic and less pessimistic than North Americans in response to negative life events. A survey was conducted to investigate optimism cross culturally in the context of the severe acute respiratory syndrome (SARS) outbreaks in Canada and China. Chinese students in Beijing and European Canadians in Toronto answered questions about their perceptions of SARS. No significant cultural difference was found on dispositional optimism, as measured by the Revised Life Orientation Test (LOT-R). Unrealistic optimism was measured in the context of SARS. Both groups demonstrated unrealistic optimism (i.e. reporting that the self was less likely than an average person to get infected with SARS). Such optimistic bias was stronger among Chinese than among Canadians. Compared to the actual infection rates in Beijing and Toronto, both Chinese and Canadian participants overestimated their own chances of getting infected, indicating that they were being pessimistic. Indeed, Chinese were less pessimistic than Canadians. In addition, even though the Chinese reported more inconvenience brought by SARS than did Canadians, they also reported more positive changes brought by SARS, reflecting the Chinese dialectical views of events. Implications for research on optimism in context are discussed.     

The psychology behind the masks: Psychological responses to the severe acute respiratory syndrome outbreak in different regions

Severe acute respiratory syndrome (SARS) was first reported in China, and spread to 29 regions, affecting over 8000 people worldwide. For the general public, the psychological impact of SARS may have been greater than the physical health danger of the disease. The present paper proposes the influence of psychological factors on people's cognitive, affective, and behavioral responses during the SARS outbreak. The various papers in this special issue of the Journal reveal how people have reacted during the SARS outbreak: People's general coping styles may be related to their health behavior during the outbreak. Cultural differences were evident in the perception of SARS, and individuals' perceptual styles may have influenced their ability to cope with the outbreak. The way in which individuals coped with SARS-related stressful events was different from their usual practices of managing daily stress. Individual differences in the adoption of preventive measures were related to the distinct susceptibility to several social-cognitive biases.     

1例妊娠合并急性白血病患者带来的分析与思考

通过对1例妊娠合并急性白血病患者的病例资料进行回顾分析,从孕期化疗的特点来探讨其终止妊娠及进一步化疗治疗的时机与方式,以及从该患者治疗和妊娠之间的矛盾来讨论医生在母体和婴儿生存权益的重要性,总结出医护人员的人性化与职责,深入伦理学思考临床医生对类似患者的最佳治疗应该作出的判定与决策,从而有利于构建和谐社会。     

非ST段抬高急性冠脉综合征药物治疗规范化分析

回顾性分析我院收治的129例非ST段抬高急性冠脉综合征患者的临床资料。对比在非ST段抬高急性冠脉综合征诊治上与最新指南的差距,找出改进措施。结果表明我院的临床实践与最新指南存在较大差距,在强化抗栓,调脂治疗,B受体阻滞剂及血管紧张素转换酶抑制荆类药物使用上均有待提高。今后应采取更加积极的措施,规范用药,以达到更好的预后和转归效果。     

肺炎支原体感染与婴幼儿哮喘

呼吸道感染是婴幼儿哮喘发病的重要因素,肺炎支原体 （mycoplasma pneumoniae,Mp） 与婴幼儿哮喘的关系是近年研究的热点之一。Mp作为社区获得性常见病原体之一在婴幼儿感染率有增高趋势。Mp感染导致婴幼儿哮喘初次和反复发作可能的机制为：Mp感染可直接损伤呼吸道上皮细胞、影响细胞及体液免疫、粘液分泌和呼吸道上皮内神经调节机制紊乱;反复发作与呼吸道对刺激因子呈现高反应性、呼吸道慢性炎症及婴幼儿特应性体质有关。大环内酯类药物具有抗炎和免疫调节作用,用于治疗Mp相关喘息性疾病时取得了一定疗效。     

急性应激障碍（ASD）研究述评

急性应激障碍是个体在亲历、目击或面临一个对自己或他人具有死亡威胁、严重伤害的创伤事件后的2天至4周内所表现的应激反应。急性应激障碍的症状主要表现为分离、再历、回避和过度警觉。文章回顾了以往的相关研究,从急性应激障碍的测评方法、发生率、与创伤后应激障碍和创伤记忆的关系、心理治疗和干预等方面进行了综述。最后对未来可能的研究方向提出了展望     

Gender differences in acute and chronic stress in Wistar Kyoto (WKY) rats

While females are considered more susceptible to depressive behavior, this assertion is not strongly supported by the experimental literature. Since stress contributes to depressive behavior, male and female Wistar Kyoto (WKY) rats were exposed to either one session (acute stress) or 5 sessions (chronic stress) of restraint plus cold in order to study depressive behavior in male and female rats. After their respective treatment exposure, rats were tested in the open field test (OFT) and for retention of a passive-avoidance (P-A) task. One stress session resulted in significant immobility in the OFT for males, whereas 5 sessions were required to produce similar immobility in female rats. Acute stress interfered with the retention of the P-A response for males, while both acute and chronic stress produced poor P-A responses in female rats. Food consumption decresed, progressively, as a function of stress sessions, in female rats, whereas feeding in males returned to control levels after five stress days. Both acute and chronic stress exacerbated the stress ulcer response in male rats, but not in female rats. Chronic, but not acute, stress resulted in an increase in serotonin transporter mRNA levels in the dorsal raphe nucleus of both male and, female rats. The general consensus from these data suggested that female rats were more vulnerable to chronic stress and consequently supported the notion that females may be more susceptible to stress induced behavioral depression.     

突发公共卫生事件下心境障碍的特点与应对

突发公共卫生事件会给较大范围的人群造成相当的心理压力和情绪问题。突发事件发生时,社会心理因素对突发事件控制效果和进程的影响越来越显著,因疫情、疾病、生活、工作以及社会和人际关系等因素而致的情绪问题非常突出。突发事件时情绪问题的表现有疑病、恐慌、焦虑、抑郁和强迫心理等,对此应采取相应的对策,而不同群体如罹患人群、隔离人群、家属、普通就医者及一般公众的情绪问题有其独特的表现和应对措施。突发事件为情绪问题的研究提供了广阔的前景。     

急性情绪应激对大鼠行为和脑神经颗粒素磷酸化水平的影响

为探讨急性情绪应激对大鼠旷场行为的影响,以及脑神经颗粒素（Neuroganin,NG）变化与应激性行为效应之间的相互关系。以急性不确定性空瓶刺激,建立情绪应激动物模型。将40只雄性SD大鼠随机分为情绪应激组1（ES1,接受情绪应激和旷场测试）、情绪应激组2（ES2,只接受情绪应激）、正常对照组1（C1,无情绪应激,但接受旷场测试）和正常对照组（C2,无情绪应激,也无旷场测试）（n=10）。以旷场行为和高架十字迷宫任务来评定大鼠应激后的行为变化,Western印迹杂交法（Western blotting）测定海马和前脑皮层中的NG含量和磷酸化水平。结果表明：（1） 应激后ES1组的水平活动增加,与C1组比较,差异有显著性, p<0.01;（2）ES1组海马和前脑皮层的NG磷酸化水平高于C1和C2组,差异有显著性, 均为p<0.05; ES2组的前脑皮层NG的磷酸化水平高于C1组,差异有显著性,为p<0.05;（3） 海马的NG磷酸化水平与水平活动之间的相关达显著水平。提示急性情绪应激能导致动物明显的行为改变如焦虑,这种行为改变可能与脑内NG磷酸化水平的变化有关。水平活动可能是反映急性情绪应激的较敏感行为指标,海马NG磷酸化水平可能是预测急性情绪应激所致焦虑或抑郁行为的较敏感生物学指标     

What happens before and after acute enactments? An exercise in clinical validation and the broadening of hypotheses

This paper seeks to validate clinical facts and theoretical hypotheses that have been discussed before and that address configurations involving chronic and acute enactments. Its validation process compares clinical material from psychoanalytic work in different psychoanalytic cultures - work from South America-Uruguay (Yardino), Europe-Spain (Sapisochin), South Africa (Ivey), Europe-UK (Bateman). It documents clinical facts described in four articles and confirms that during chronic enactments the analytic dyad gets caught up in a dual relationship that veils and congeals the triangular situation because acknowledging it would be traumatic. The lack of triangular space impedes the formation of symbols as well as dreaming and creates non-dreams-for-two. During chronic enactments analysts use their implicit alpha-function to assemble traumatic areas. These areas emerge as a mix of discharges and non-dreams that are dreamed through acute enactments. Acute enactments occur when chronic enactments dissolve and patients experience an abrupt contact with reality. The attenuated trauma is then dreamed alive. The linking of new symbols develops a network of symbolic thought and creates dreams-for-two and broadens the patient's mental universe. The validation process has deepened our vision concerning clinical facts, especially in relation to: (1) the wavering between acute and chronic enactments, (2) analysts' inhibitions and feelings of guilt, and (3) the influence of analysts' personalities on the configurations they describe. These theoretical hypotheses have been confirmed and broadened not only in relation to the vicissitudes of dream work in traumatic areas, but also in relation to defenses such as thin or thick skin, and in relation to listening in countertransferential detours.