急性心肌梗死患者PCI术后无复流的相关因素探讨

探讨急性心肌梗死(AMI)患者PCI术后发生无复流的的相关因素.入选急诊PCI术中血管造影显示无复流患者110例入选无复流组;纳入同期行急诊PCI术经冠脉造影示血流正常的患者110例为正常血流组,搜集相关数据并进行单因素与二分类Logistic回归分析,再通过ROC曲线探讨入院后EPO对无复流发生的预测价值.最后显示EPO、血糖、中性粒细胞计数是无复流的独立预测因素;ROC曲线下面积0.75.当截点值取14.21mIU/ml时,EPO对PCI术后发生无复流预测价值较高.     

Interpreting coronary-prone behaviour: Relationships among type a behaviour,hopelessness, anger management and social contact

Abstract

Two approaches to interpreting relationships among psychosocial risk factors for coronary heart disease are contrasted: the profile approach which focuses on predictive validity and confounding; and the theoretical approach which emphasises internal validity. These approaches are explored by applying them to a set of correlations found among Type A behaviour, hopelessness, anger management and social contact in a female sample. Type A behaviour was positively correlated with hopelessness and with anger expression, whilst anger management was related to the availability of social contact. The relationships between Type A, anger expression and hopelessness also appeared to be moderated by degree of social contact. These results are interpreted from the profile perspective and from that of Price's cognitive social learning theory. The relative merits of the two approaches are considered and a case is made for encouraging more theoretically based research on coronary-prone behaviour.     

Effects of a post-hospitalization group health education programme for patients with coronary heart disease

Abstract

Effects of a post-hospitolization group health education programme for patients with coronary heart disease. A health education programme was offered to groups of coronary heart patients and their partners after discharge from hospital. A randomized pre-test post-test control group design was used to evaluate the effects of this experimental intervention. The health education programme was offered to 109 coronary heart patients in groups of between five and eight patients together with their partners in addition to standard medical care and physical training. A control group of 108 patients received only standard medical care and physical training.

The intervention consisted of eight weekly two-hour group health education sessions and one follow-up session. All sessions focused on the promotion of healthy habits and the reduction of adverse psychosocial consequences of the incident.

In the short term (about four months after the incident) the health education programme showed statistically significant intervention effects on knowledge about coronary heart diseases, smoking cessation, healthy eating habits and the number of consultations with the family physician, but no effects on emotional distress. In the long term (one year after the incident) there was only a significant intervention effect on smoking cessation.

These results suggest that the effects of the programme are modest, especially in terms of maintenance of behavioural change. As a consequence, it is suggested that the programme should not be offered to all coronary patients during cardiac rehabilitation, but only to those who can be expected to profit most from it.     

Vital exhaustion measures and their associations with coronary heart disease risk factors in a sample of spanish-speakers

Abstract

The main purpose of this research was to study the reliability and conceptual validity of two Spanish language measures of Vital Exhaustion (VE), a short-term risk factor for coronary artery disease (CAD). The English version of the Maastricht Questionnaire for Vital Exhaustion was used to make a Spanish language questionnaire (VEQ) and a Spanish language interview (VEI) whose scoring systems were equal to the original version. These instruments were administered to a sample of healthy working men (n = 100) and women (n = 130) in Caracas, Venezuela. Participants also completed questionnaires designed to measure anger-expression and social support and were assessed by means of the Structured Interview to measure Type A Behaviour Pattern (TABP). Information about other CAD-risk factors, such as age, smoking behavior, and health habits, were collected.

High reliability coefficients, .85 and .91, were found for the VEI and VEQ, respectively. Principal component analysis provided one-factor solutions for each instrument. The pattern of correlations between VE, assessed by the VEI, and other personality characteristics was rather similar to the pattern observed in other cultures. In general significant, but modest, correlations were observed between VE and TABP, anger expression, a negative self-concept, and low social support. We conclude that VE appears to be a meaningful construct in this particular cultural context.     

Psychometric properties of the Type D scale (DS14) in Norwegian cardiac patients

Bergvik, S., Sørlie, T., Wynn, R. & Sexton, H. (2010). Psychometric properties of the Type D scale (DS14) in Norwegian cardiac patients. Scandinavian Journal of Psychology. The combination of negative affectivity (NA) and social inhibition (SI) – the Type D Personality – is associated with poor outcomes in coronary artery disease (CAD) patients. A Norwegian translation of the standard instrument measuring Type D (DS14) was tested on 432 CAD patients receiving coronary revascularization treatment. Factor analysis produced two factors with high inter‐item reliability, indicating that the Norwegian DS14 has acceptable psychometric properties. Eighteen percent were classified as Type D, lower than has been reported elsewhere. Type D was associated with anxiety, depression, and passive coping. NA correlated positively with depression, anxiety, and passive coping. SI correlated positively with depression and anxiety, and negatively with active coping. The prevalence of Type D was higher among women, and negatively correlated with time since treatment. The variation in Type D prevalence among studies needs further elucidation as does the predictive power of continuous scoring of the Type D trait.     

心脏冠状动脉多层CT检查——临床上我们是否应用得当?

心脏冠状动脉多层CT扫描目前在对心脏进行整体扫描进而发现冠状动脉狭窄或冠状动脉钙化方面应用较多,但从经济费用-临床效益比值考虑,是否所有患者均需进行此项检查值得商榷。为降低患者就诊成本,我们认为,对于年轻非糖尿病患者可先根据Framingham冠心病危险量表进行测算患者未来10年出现冠心病的危险度,如果根据此量表计算的患者未来10年出现冠心病的危险度10%的中度以上危险度的患者,才应该给予心脏冠状动脉多层CT扫描检查以了解其是否需要进一步深入治疗。     

从冠心病主要危险因素的流行特点谈医学模式的转变

随着人民生活水平的提高,冠心病的发病率呈逐年上升趋势,不仅造成个人很高的致残率或致死率,而且给家庭和社会带来沉重的经济负担,冠心病已成为当前一个重要的公共卫生问题。而冠心病是一个多病因疾病,是可防可控的。充分了解冠心病危险因素的流行现状及危害,转变理念,着眼预防,逐步改变目前"重治轻防"的医学模式,是我们心血管医生神圣的使命。     

冠心病患者对比剂诱发肾病的临床研究

为了比较两种水化方法对对比剂肾病(CIN)的影响,我们选住院行经皮冠状动脉介入治疗(PCI)94例肾功能不全患者,随机分为氯化钠水化组、碳酸氢钠水化组测定术后4天血肌酐水平变化。结果显示,氯化钠水化组6例发生CIN(13.3%),碳酸氢钠水化组3例CIN(6.3%),提示对于慢性肾功能不全患者碳酸氢钠水化方案更优。     

妊娠期急性脂肪肝诊治中的科学思维应用

现代科学思维方法中系统思维及模糊思维方法具有普遍适用意义。妊娠期急性脂肪肝临床上极为罕见,并发症多,病死率极高,1例并发腹部卒中的妊娠期急性脂肪肝患者通过科学诊疗转危为安,及时终止妊娠、对症处理、多学科协作联合治疗,积极预防并发症是确保救治成功的关键。本文尝试介绍科学思维方法在该病诊疗中的一些体会。     

20]0版欧洲心肌再血管化指南解读

2010年9月欧洲心脏病协会（ESC）和欧洲心胸外科协会（EACTS）领导下的联合项目组、指南委员会及其评审专家共N起草的一份经多方权衡、以患者为中心、以证据为导向的关于心肌再血管化治疗的操作指南。指南涉及冠心痛患者的评估、治疗决策、二级预防等,第一次将冠状动脉旁路移植和经皮介入治疗在同一指导性文件中加以讨论。为利于临床医师阅读,撰写本指南解读。