肿瘤疫苗治疗肿瘤的前景

肿瘤疫苗的发展已经历了一个多世纪,20世纪50年代,人们开始了自体肿瘤疫苗的研究.使肿瘤疫苗(主动性免疫治疗)成为继手术、放疗、化疗之后的肿瘤治疗方法.肿瘤疫苗作为主动特异性免疫治疗,在临床中起到越来越重要的作用,人们开始尝试利用多种方法制备肿瘤疫苗并利用其促进机体免疫应答,从整体细胞,分子水平调控机体对肿瘤的免疫.目前肿瘤疫苗的研制已取得很大进展,给人类战胜肿瘤提供很大希望。     

Countertransference as active imagination: imaginative experiences of the analyst

Active imagination is at the heart of Jung's elucidation of depth psychology. Yet, in the discourse of present day analytical psychology theory it is not always given the serious attention accorded to some other Jungian concepts. Active imagination emerges spontaneously within the 'third' area--the imaginal or dynamic field--in-between patient and analyst. It is commonly regarded as the patient's experience but I am proposing that, looked upon as the analyst's experience as well, active imagination offers a distinctly Jungian way of understanding some forms of countertransference. I am describing what I think many present-day analytical psychologists already do in their clinical practice but, as far as I know, it has not been theorized in quite this way before. The intention is to exploit the unique contribution of our Jungian heritage by reframing certain profoundly symbolic countertransference-generated imagery as active imagination. In this article these are differentiated from other less complex forms of imaginative countertransference through examples from clinical practice. The point is that such countertransference experiences may activate the symbolic function in the analyst and thus contribute to the mediation of emergent consciousness in the analysand.     

Recovery and Renewal: Journey of Hope to the Gulf Coast

When a group of 20 college students and seven adult leaders traveled to the Gulf Coast to repair houses damaged by Hurricane Katrina, they did not realize the multiple ways that they themselves would be renewed. Finding God in the struggle, celebrating diversity, and living with gratitude became the result that subtly changed many lives. Fredrica R. Halligan, Ph.D. is a spiritually-oriented clinical psychologist. She is currently Director of the Counseling Center at Western Connecticut State University and author of Listen Deeply to God: Exploring Spirituality in an Interreligious Age.     

Naturalistic Recovery From Nonsuicidal Self‐Injury: A Phenomenological Inquiry

The authors conducted a phenomenological inquiry of 12 individuals who recovered from nonsuicidal self‐injury without psychotherapeutic or medical intervention. Results indicated that participants’ naturalistic recovery emanated from their recognition of serious physical damage, corrective interpersonal influences, and movement from unhealthy to healthy surroundings. Implications of these findings for clinical practice and future research are discussed.     

右美托咪定对鼻内镜手术患者血流动力学及苏醒期的影响

探讨鼻内镜手术时应用右美托咪定对其血流动力学及苏醒期的影响。选择100例行鼻内镜的择期手术患者,随机分为两组,右美托咪定组（D组）,持续泵入右美托咪定0.4μg·kg-1·h-1从麻醉诱导开始到拔管结束;对照组（C组）,持续泵入相同剂量的生理盐水。诱导药物均为依托咪酯0.3mg/kg,舒芬太尼0.4μg/kg,罗库溴铵0.6mg/kg,术中以丙泊酚6mg·kg-1·h-1、瑞芬太尼0.1μg·kg-1·min-1维持。观察并记录诱导前5min,手术开始后10min及30min,手术结束时,拔管时及拔管后2min的MAP及HR;记录术野质量和术中出血量、手术时间和拔管时间、拔管时躁动的发生率、呛咳评分、拔管后患者的Ramsay镇静评分。结果 D组在拔管时及拔管后2min血压和心率与C组相比降低（P〈0.05）;D组的术野质量优于C组（P〈0.05）,术中出血量D组少于C组（P〈0.05）;两组的手术时间和拔管时间差异无统计学意义;拔管时躁动的发生率及呛咳评分D组低于C组（P〈0.05）;D组拔管后患者的Ramsay镇静评分高于C组（P〈0.05）。术中应用右美托咪定,可使鼻内镜手术患者术中血流动力学更稳定,苏醒期更为平稳。     

Guidance systems across Europe: heritage,change and the art of becoming

Guidance systems exist within learning, working and welfare cultures, which are upheld by prevailing institutions and stakeholders. Implementing a lifelong approach questions rooted codes and idiosyncrasies of the sectors across which guidance is distributed. To support individuals' careers, unlock their potential and increase their contribution to the economy i.e. support their process of becoming, lifelong guidance must strive for effective systems' integration across policy fields, cultures and organisations. This article departs from national experiences and discusses how cultures and institutional contexts generate resistance to change, but can also be the departure point for the successful development of lifelong support to people's careers.     

Psychology Without Psy Professionals: Exploring an Unemployed Centre Families Project as a Mental Health Resource

The activities and technologies of the psychology (Psy) disciplines, in the process of privileging professional understandings of distress, could be seen to be potentially facilitating corrosion in the capacity of the lay public to understand and ameliorate their distress. This paper draws on the experiences of people who use an Unemployed Centre Families Project in the South of England to provide an example of community mental health work that does not draw on the dominant discourses, institutions or practitioners of the Psy sciences. Through interviews with centre users, staff and volunteers, a picture emerges of a community space that provides a variety of services, projects and opportunities that have a very considerable positive impact on the mental well‐being of the centre users. This picture highlights non‐medical intersubjective processes that offer possibilities for recoveries from mental distress but that are often neglected and subordinated in the professional worlds of Psy and psychiatry. Such centres facilitate social networks and practical help, and transitions in identity can be beneficial for those experiencing mental distress. In so doing, they make prominent some of the key limitations of biomedical approaches to recovery. Copyright © 2015 John Wiley & Sons, Ltd.     

Know before whom you stand: Mikael Enckell’s Companions of the Unknown [Okändhetens följeslagare]

Mikael Enckell’s book is discussed as a combined self-analytic tour de force and psychoanalytic supplement to Jewish philosophy represented by Frans Rosenzweig and others. The author discusses Enckell’s views on the roots of psychoanalysis in Jewish thought, anti-Semitism, historiography, the importance of human dialogue, revelation and psychic integration, atheism, and the nature of recovery in psychoanalysis. Enckell’s views of a triad of human activities open to conflict and ambiguity – Judaism, poetry, and psychoanalysis – are supplemented by a short discussion on the role of annihilation anxiety in these areas.