听而不“闻”?人声失认症的神经机制

人声身份识别对于社交交流的许多方面都至关重要, 大多数个体都能根据声音识别其声源者, 然而人声失认症患者似乎已经丧失了这种能力。人声失认症是指人声身份加工的不同阶段出现障碍, 症状主要包括获得性人声失认症, 发展性人声失认症及其亚型。获得性人声失认症患者受损脑区主要包括颞叶, 赫氏脑回和颞极, 发展性人声失认症主要与右后侧颞上沟的非典型性反应和颞叶与杏仁核间的功能联结障碍有关。以后的研究可以重点关注人声失认症的筛选方法, 界定范围和文化差异等方面。     

The Influence of Acetaminophen and Observational Conditioning on the Acquired Capability for Suicide

The effects of acetaminophen and a reading task on physical pain tolerance and fearlessness about death were tested in 106 undergraduate students. Participants were randomized into four groups, each receiving either acetaminophen or no medication, along with either a control or experimental reading task. It was predicted that acetaminophen would increase pain tolerance and fearlessness about death, that the experimental reading task would decrease both outcomes, and that the interventions would interact (i.e., acetaminophen would dampen the effects of the reading task). Multivariate analysis of variance was used to test hypotheses. No significant interaction was found (p = .17) and there was no effect for acetaminophen (p = .56), but individuals administered the experimental reading task demonstrated significantly higher physical pain tolerance (p < .05).     

The long-term outcome of a personal network-oriented HIV prevention intervention for injection drug users: The SAFE study

Social influence processes have been found to affect numerous drug and health-related behaviors. We postulated that by using a network-oriented intervention it may be possible to capitalize on social influence processes to reduce human immunodeficiency virus (HIV) risk behaviors. The present study used an experimental study design for delivering a psychoeducational acquired immunodeficiency syndrome (AIDS) preventive intervention to injection drug sharing networks. Participants were recruited from the ALIVE study, an epidemiological study in Baltimore. In the present paper we examine the self-reported behavioral outcomes of 117 injection drug users 18 months after the baseline interview. HIV seronegative experimental participants reported significantly less frequent needle sharing and less injecting of heroin and cocaine than controls. In multiple logistic regression models of HIV seronegative participants, there was a significant negative association between assignment to the experimental group and the HIV-related behaviors of needle sharing and sharing of cookers in the prior 6 months; controls were 2.8 times more likely than experimentals to report needle sharing and were 2.7 times more likely to report sharing cookers. The results of this 18-month follow-up suggest that among injection drug users network-oriented interventions may be a promising approach to HIV prevention.     

RELIGION VERSUS SCIENCE: THE CONFLICT IN REFERENCE TO TRUTH VALUE,NOT CASH VALUE

Abstract. The rift between science and religion needs to be assessed not merely on pragmatic grounds, on the basis of the effect of scientific versus religious beliefs on people's behavior, as John Caiazza's essay does, but also and above all in regard to the cogency of the respective beliefs in reference to what we can reasonably assume is the true face of reality. About such truth value, the conflict is not irremediable; there are elements of belief regarding the nature of reality that are strikingly similar regardless of whether one arrived at them on the basis of faith in revealed knowledge or on the basis of knowledge acquired by reasoning from or in reference to experience. Two such items are selected here by way of example: belief that in certain states of mind and consciousness individuals can experience union with something larger or deeper than themselves, and belief that the universe we inhabit is the result of an original creative act.     

Rapid word identification in pure alexia is lexical but not semantic

Following the notion that patients with pure alexia have access to two distinct reading strategies-letter-by-letter reading and semantic reading-a training program was devised to facilitate reading via semantics in a patient with pure alexia. Training utilized brief stimulus presentations and required category judgments rather than explicit word identification. The training was successful for trained words, but generalized poorly to untrained words. Additional studies involving oral reading of nouns and of functors also resulted in improved reading of trained words. Pseudowords could not be trained to criterion. The results suggest that improved reading can be achieved in pure alexia by pairing rapidly presented words with feedback. Focusing on semantic processing is not essential to this process. It is proposed that the training strengthens connections between the output of visual processing and preexisting orthographic representations.     

The contextually controlled, feature-mediated classification of symbols

The classification of names of people or objects based on the features acquired by the names and the sorting instructions provided is a commonplace occurrence. For example, given the names Renoir, Pollock, James and Voltaire the average adult would be able to classify them differentially based on the instruction to classify them based on vocation or nationality. In general, such a repertoire reflects the reclassification of symbols (i.e, the names of individuals) in terms of contextual cues (instructions to sort by vocation or nationality) and the features acquired by the symbols (the specific nationalities and vocations). The present experiment studied this phenomenon with the use of arbitrary stimuli that did not have clear preexperimental associations. Two of 4 participants classified the symbols into different equivalence classes based on the prevailing contextual cues and the features that had been acquired by the symbols. Using an ABA reversal design we then demonstrated that 1 participant classified the symbols in accordance with the contextual cues and acquired features when present, but not in the absence of the contextual cues. A 3rd participant showed symbol classification that differed from that predicted by the procedures, and the 4th classified the symbols based on one set of features but not on context. These data describe one set of conditions that could account for the establishment of complex classification repertoires that occur in natural settings.