消费者对犯错品牌评价的时间打折效应及其影响因素

通过研究品牌犯错的时间打折效应,本文试图探讨潜在消费者（未购买者）对犯错品牌评价的心理倾向。实验1研究发现,随着品牌犯错事件时间距离的延伸,消费者对身体性危害-品牌犯错的评价不会改善,即没有出现时间打折效应,而对功能性危害-品牌犯错的评价则逐渐提高,从而表现出时间打折效应。但实验2研究进一步发现,随着品牌犯错事件相关性的增强,功能性危害-品牌犯错的时间打折效应也消失。结论：潜在消费者对犯错品牌评价的心理倾向表现为“消费者防御”,并且身体性危害-品牌犯错启动的消费者防御要强于功能性危害。     

趋近和回避动机的区分及其对心理病理学的影响

趋近和回避是动机的两种最基本形式, 反映着个体与环境的相互作用方式, 是个体适应环境的核心机能。回避动机保证了个体的生存, 趋近动机则促进个体的成长。两类动机系统在前额叶皮层呈不对称偏侧化分布, 趋近动机与左侧额叶皮层激活相连, 回避动机与右侧额叶皮层激活相连。Youngstorm 和Izard等认为两类动机系统失调可能与一系列的情绪和行为问题有关, 如躁狂、抑郁、焦虑和儿童多动症等。这一观点已得到一些相关研究和临床研究证实。建议未来研究关注趋近-回避动机区分与情绪和认知功能研究的融合, 进一步检验趋近-回避动机系统失调模型, 并加强趋近和回避动机系统的可塑性研究。     

教师关怀行为与学生学业成绩的关系:学习效能感的中介作用

采用教师关怀行为问卷、学生学习效能感问卷调查1430名中学生,考察教师关怀行为、学生学习效能感和学业成绩之间的关系.结果发现:(1)教师关怀行为的得分高于“3”,达到了3.54;学生的学习效能感的得分也比较高,得分为3.73;(2)教师关怀行为、学生学习效能感和学生的学业成绩及其各维度之间存在着显著的正相关;(3)学生学习效能感在教师关怀和学生的学业成绩之间起着部分中介作用,其中介效应值为0.25,并且学习效能感的两个维度中的学习能力效能感的中介效应(效应值为0.18)大于学习行为效能感(效应值为0.04)的中介效应.     

教师自主支持与初中生的学习投入:家庭社会阶层与学生自主动机的影响

采用学习氛围量表、主观社会阶层量表、学业调节问卷和修订的课堂投入问卷对1211名初中生进行调查,根据主观社会阶层得分在3分以下、6分以上的标准,筛选出491名典型低阶层(374人)与高阶层(117人)被试,考察教师自主支持与初中生学习投入的关系,以及学生自主动机在其中的中介作用和家庭社会阶层的调节作用.结果表明:(1)教师自主支持与初中生的学习投入之间存在显著正相关;(2)自主动机在教师自主支持与初中生的学习投入之间起部分中介作用;(3)家庭社会阶层在教师自主支持影响初中生自主动机进而影响其学习投入的过程中起到有中介的调节作用.     

家长投入对中小学生学业投入的影响:有中介的调节模型

以北京市12所中小学的4160名学生为调查对象,采用层次回归方法考察了家长投入对子女学业投入的影响以及家长自主支持/控制的教养风格和子女的学业心理需要满足在其中的作用。结果发现:(1)中小学生的家长投入程度随学段升高而降低;(2)家长注重在家辅导方面的投入,在参与社区及学校活动等方面的投入较为欠缺;(3)家长投入对子女的学业投入具有显著的正向预测作用;(4)家长自主支持/控制的教养风格在家长投入与子女学业投入的关系中起调节作用,且该调节效应部分地通过子女的学业心理需要满足这一中介变量产生作用。     

Ethanol state-dependent memory: involvement of dorsal hippocampal muscarinic and nicotinic receptors

In the present study, the effects of bilateral injections of cholinergic agents into the hippocampal CA1 regions (intra-CA1) on ethanol state-dependent memory were examined in mice. A single-trial step-down passive avoidance task was used for the assessment of memory retention in adult male NMRI mice. Pre-training intraperitoneal injection (i.p.) of ethanol (0.25, 0.5 and 1 g/kg) dose dependently induced impairment of memory retention. Pre-test administration of ethanol (0.5 and 1 g/kg, i.p.) induced state-dependent retrieval of the memory acquired under pre-training ethanol (1 g/kg, i.p.) influence. Pre-test intra-CA1 injection of physostigmine (2.5 and 5 μg/mouse, intra-CA1) or nicotine (0.3 and 0.5 μg/mouse, intra-CA1) improved pre-training ethanol (1 g/kg)-induced retrieval impairment. Moreover, pre-test administration of physostigmine (2.5 and 5 μg/mouse, intra-CA1) or nicotine (0.3 and 0.5 μg/mouse, intra-CA1) with an ineffective dose of ethanol (0.25 g/kg) significantly restored the retrieval and induced ethanol state-dependent memory. Pre-test intra-CA1 injection of the muscarinic receptor antagonist, atropine (4 and 8 μg/mouse, intra-CA1) or the nicotinic receptor antagonist, mecamylamine (2 and 4 μg/mouse, intra-CA1) 5 min before the administration of ethanol (1 g/kg, i.p.) dose dependently inhibited ethanol state-dependent memory. Pre-test intra-CA1 administration of physostigmine (0.5, 2.5 and 5 μg/mouse), atropine (2, 4 and 8 μg/mouse), nicotine (0.1, 0.3 and 0.5 μg/mouse) or mecamylamine (1, 2 and 4 μg/mouse) alone cannot affect memory retention. These findings implicate the involvement of a dorsal hippocampal cholinergic mechanism in ethanol state-dependent memory and also it can be concluded that there may be a cross-state dependency between ethanol and acetylcholine.     

Rigidity in social and emotional memory in the R6/2 mouse model of Huntington's disease

Four experiments were conducted to examine social and emotional memory in the R6/2 transgenic mouse model of Huntington’s disease. First, R6/2 mice were tested in a social transmission of food preference task where they had to acquire a preference for a flavoured food (acquisition) and subsequently to learn a preference for a different flavour (shifted reinforcement). R6/2 mice performed well in the acquisition trial. However, they were impaired in the shifted reinforcement trial and perseverated on the first preference learned. Second, mice were trained in an inhibitory avoidance paradigm, with either one or two footshocks delivered during the training. WT mice given one footshock showed retention levels lower than those of mice trained with two footshocks. By contrast, there was no difference in retention levels of R6/2 mice given either one or two footshocks. Third, mice were tested in an active avoidance task that paired a mild footshock with a warning light. R6/2 mice had a strong age-dependent deficit in this task. Finally, mice were tested in a conditioned taste aversion task that paired a saccharine solution with a nausea-inducing agent (LiCl). R6/2 mice displayed normal aversion, however this was not extinguished following repeated exposure to saccharine solution alone. Our data show that while R6/2 mice have functional hippocampus-based memory, they have deficits in striatum-based memory skills. Further, social and emotional memories appear to be encoded in a rigid way that is not influenced by subsequent learning or by arousal levels.     

Upregulation of hippocampal TrkB and synaptotagmin is involved in treadmill exercise-enhanced aversive memory in mice

Cognitive functions usually involve various synaptic proteins and neurotrophic factors in the hippocampus. However, whether treadmill exercise can improve learning and memory by upregulating some of these molecules remain unraveled. To address this question, male BALB/c mice were divided into control and exercise groups, the latter group went through 4 weeks of treadmill exercise training. At the end of exercise training period, they were either tested for passive avoidance (PA) performance or sacrificed for quantifying the hippocampal levels of brain-derived neurotrophic factor (BDNF), tropomyosin-related kinase B (TrkB, the BDNF receptor), synaptotagmin (a Ca²⁺-dependent synaptic vesicle protein), and SNAP-25 (a presynaptic vesicular fusion protein). Our results showed that treadmill exercise training (1) increased the retention latency without affecting the fear acquisition in the PA test, (2) transiently increased the hippocampal BDNF level at 1, 2, and 4 h after the completion of exercise training, and (3) persistently increased the hippocampal protein levels of full-length TrkB, phosphorylated TrkB and synaptotagmin, but not truncated TrkB or SNAP-25. Moreover, the protein expression level of full-length TrkB or synaptotagmin was positively correlated with PA performance in mice. Finally, inhibition of TrkB signaling by K252a abolished the exercise-facilitated PA performance and upregulation of TrkB and synaptotagmin. Taken together, these data suggest that the upregulation of TrkB and synaptotagmin in the hippocampus contributes to the exercise-facilitated aversive memory.     

Avoidance of timeout from response-independent food: effects of delivery rate and quality

In three experiments, a rat's lever presses could postpone timeouts from food pellets delivered on response-independent schedules. In Experiment 1, the pellets were delivered at variable-time (VT) rates ranging from VT 0.5 to VT 8 min. Experiment 2 replicated the VT 1 min and VT 8 min conditions of Experiment 1 with new subjects. Finally, subjects in Experiment 3 could postpone timeouts from delivery of pellets that differed in quality rather than quantity (unsweetened versus sweetened pellets). In general, response rates and success in avoiding increased as a function of the rate and quality of the pellets. Also, performance efficiency increased as the experiments progressed, that is, the avoidance response occurred later and later in the response-timeout interval. The results support the conclusion that timeout from reinforcement has functional properties similar to those of more commonly studied aversive stimuli (e.g., shock).     

必须关注防止医学领域内的唯心科学观

对医学科学领域内存在的和某些一度充斥的唯心科学观的社会表现进行分析,从过程管理和科学方法论的重要性入手,提出防范学术腐败和发展医学科学的方法和措施,从教育和民生的角度探讨医务工作者和社会学家必须关注的医学领域内的唯心科学观,并举例说明医学工作者的科学道德自律和社会责任感的重要性。