A comparison of conflict of interest policies at peer-reviewed journals in different scientific disciplines

Scientific journals can promote ethical publication practices through policies on conflicts of interest. However, the prevalence of conflict of interest policies and the definition of conflict of interest appear to vary across scientific disciplines. This survey of high-impact, peer-reviewed journals in 12 different scientific disciplines was conducted to assess these variations. The survey identified published conflict of interest policies in 28 of 84 journals (33%). However, when representatives of 49 of the 84 journals (58%) completed a Web-based survey about journal conflict of interest policies, 39 (80%) reported having such a policy. Frequency of policies (including those not published) varied by discipline, from 100% among general medical journals to none among physics journals. Financial interests were most frequently addressed with relation to authors; policies for reviewers most often addressed non-financial conflicts. Twenty-two of the 39 journals with policies (56%) had policies about editors’ conflicts. The highest impact journals in each category were most likely to have a published policy, and the frequency of policies fell linearly with rank; for example, policies were published by 58% of journals ranked 1 in their category, 42% of journals ranked third, and 8% of journals ranked seventh (test for trend, p = 0.003). Having a conflict of interest policy was also associated with a self-reported history of problems with conflict of interest. The prevalence of published conflict of interest policies was higher than that reported in a 1997 study, an increase that might be attributable to heightened awareness of conflict of interest issues. However, many of the journals with policies do not make them readily available and many of those policies that were available lacked clear definitions of conflict of interest or details about how disclosures would be managed during peer review and publication.     

Defining Financial Conflicts and Managing Research Relationships: An Analysis of University Conflict of Interest Committee Decisions

Despite a decade of federal regulation and debate over the appropriateness of financial ties in research and their management, little is known about the actual decision-making processes of university conflict of interest (COI) committees. This paper analyzes in detail the discussions and decisions of three COI committees at three public universities in California. University committee members struggle to understand complex financial relationships and reconcile institutional, state, and federal policies and at the same time work to protect the integrity of the scientific process, the autonomy and intellectual freedom of their faculty colleagues and students, and the financial interests of the university.     

浅析基因治疗临床试验中的"利益冲突"

基因治疗临床试验中的"利益冲突"问题多聚焦在如何规范利益冲突的不良后果上,却忽视了一些更基本的问题,如临床试验中的不同"利益",利益冲突的表现及防范等.以基因治疗为例,归纳了临床试验中的不同利益和利益冲突形式,并指出"公开经济利益安排"是解决冲突的基本对策.     

评估职业兴趣的结构

Holland的职业兴趣理论对当今兴趣研究产生了广泛、深远的影响。但是目前,还没有研究考察Holland理论假设在中国的适用性。研究共检验了5个与Holland的6种兴趣类型(RiASEC)有关的假设,其中两个是由本文研究者提出。研究搜集了在中国进行的、与Holland理论有关的研究,并最终选择了9个RIASEC相关矩阵。假定顺序的随机化检验以及方差分析的结果表明,Holland的圆形假设与数据的拟合程度在5个模型中最差;多维标度法结果表明,RIASEC的空间结构图并没有很好地符合Holland的圆形假设。     

The Impact of Test Outcome Certainty on Interest in Genetic Testing Among College Women

Osteoporosis and hemochromatosis are both late-onset preventable diseases, but future genetic tests for these conditions are likely to differ in their predictive abilities. To determine whether interest in a specific genetic test for hemochromatosis would be higher than interest in a theoretical test for osteoporosis susceptibility, undergraduate women at the University of Cincinnati (N = 181) were surveyed regarding their interest in genetic testing for these conditions. The clinical features of the diseases and the limits of a genetic test for each were described. Sixty-three percent of the total population was interested in genetic testing with a trend toward higher interest in the osteoporosis group. Disease familiarity, perceived disease severity, and perceived risk for disease appear to be more important predictors of genetic test acceptance than diagnostic specificity. Suggested implications for the development of population genetic screening tests are discussed.     

大学生问题发现过程的眼动研究

在潜藏式与矛盾式两类问题发现情境中, 以眼动仪为研究工具, 问题发现能力高与低的大学生各20名为被试, 探讨大学生在问题发现总体和4个兴趣区中的眼动特征及其与发现问题数量和质量之间的关系。研究表明：(1)不同能力大学生在不同情境及其兴趣区中的问题发现差异, 能够体现在眼动指标上。回视是反映问题发现能力的敏感指标。回视次数和发现问题数量与质量之间的正相关, 以及在高能力组学生上的优势, 体现了信息的联系和整合性加工在问题发现中具有积极意义。(2)潜藏式问题发现中, 个体平均注视时间更长, 反映其认知加工难度更大。在提供重要信息的区域, 被试会投入更多精力, 表现为在注视时间、注视次数和瞳孔直径大小等指标的上升。(3)眼睛注视区域与发现问题区域间存在对应关系, 显示出“眼随心动”现象。在问题发现的最初和最终阶段, 被试都会出现跨区信息搜寻行为, 分别代表了对问题线索的寻找和最后的检查评估。高能力被试在每个稳定注视阶段的注视时间更短, 这种信息转换的灵活性体现出其信息加工上的优势。动态眼动轨迹分析揭示了单个静态指标难以反映的新特点。     

Not strange but not true: self-reported interest in a topic increases false memory

People are more likely to recall both true and false information that is consistent with their pre-existing stereotypes, schemata and desires. In addition, experts in a particular field are more likely to experience false memory in relation to their area of expertise. Here, we investigate whether level of interest, as distinct from level of knowledge, and in the absence of self-professed expertise, is associated with increased false memory. 489 participants were asked to rank 7 topics from most to least interesting. They were then asked if they remembered the events described in four news items related to the topic they selected as the most interesting and four items related to the topic selected as least interesting. In each case, three of the events depicted had really happened and one was fictional. A high level of interest in a topic increased true memories for the topic and doubled the frequency of false memories, even after controlling for level of knowledge. We interpret the results in the context of the source-monitoring framework and suggest that false memories arise as a result of interference from existing information stored in domain-related schemata.     

Taking Conflicts of Interest Seriously without Overdoing It: Promises and Perils of Academic-Industry Partnerships

Academic-industry collaborations and the conflicts of interest (COI) arising out of them are not new. However, as industry funding for research in the life and health sciences has increased and scandals involving financial COI are brought to the public’s attention, demands for disclosure have grown. In a March 2008 American Council on Science and Health report by Ronald Bailey, he argues that the focus on COI—especially financial COI—is obsessive and likely to be more detrimental to scientific progress and public health than COI themselves. In response, we argue that downplaying the potential negative impact of COI arising out of academic-industry relationships is no less harmful than overreacting to it.

医务人员在医疗活动中的利益边界与道德责任分析

当今是一个以利益为轴心的时代,利益伦理是医学伦理学不可忽视的课题。欲望是无穷的,利益是有限的,任何利益都有其边界和限度,我们必须设置利益的道德界限。医患双方未能遵守利益限度和利益边界原则,使矛盾转化为冲突。利益冲突不仅影响医生的专业判断,而且影响了其医疗决定。医生既是医疗职业者,也是社会的一员,社会公众利益最大化是医疗服务的基本目标,为病人最大利益着想是医护专业最根本的道德规范与责任。     

伦理智慧视野中的企业竞争与企业社会责任

在市场经济发展中,应树立正确的竞争意识,避免导致企业灾难的恶性竞争。企业应在有合作的竞争中,在追求“内在利益”的经营中实现“双赢”。唤起企业的社会责任是企业伦理建设的重要内容。伦理智慧在企业竞争中,在追求"内在利益"中,在承担社会责任中表现出来。