Medial prefrontal cortex lesions abolish contextual control of competing responses

There is much debate as to the extent and nature of functional specialization within the different subregions of the prefrontal cortex. The current study was undertaken to investigate the effect of damage to medial prefrontal cortex subregions in the rat. Rats were trained on two biconditional discrimination tasks, one auditory and one visual, in two different contexts. At test, they received presentations of audiovisual compounds of these training stimuli in extinction. These compounds had dictated either the same (congruent trials) or different (incongruent trials) responses during training. In sham-operated controls, contextual cues came to control responding to conflicting information provided by incongruent stimulus compounds. Experiment 1 demonstrated that this contextual control of responding was not evident in individual rats with large amounts of damage that included the prelimbic and cingulate subregions of the prefrontal cortex. Experiment 2 further dissociated the result of Experiment 1, demonstrating that lesions specific to the anterior cingulate cortex were sufficient to produce a deficit early on during presentation of an incongruent stimulus compound but that performance was unimpaired as presentation progressed. This early deficit suggests a role for the anterior cingulate cortex in the detection of response conflict, and for the medial prefrontal cortex in the contextual control of competing responses, providing evidence for functional specialization within the rat prefrontal cortex.     

青少年亲子冲突的研究现状

青少年时期是人生中最关键而富有特色的时期,是个体由不成熟的童年向成熟人生过渡的时期。过渡性往往和不稳定性联系在一起,因此,青少年时期容易产生亲子冲突,被有的学者称之为“亲子关系危机期”、“疾风暴雨”期。且目前我国青少年亲子冲突愈演愈烈,针对此现象,本文从亲手冲突的特点、影响因素方面进行综述,以期对我国目前正开展的此领域研究提供一些思考和借鉴。     

Everyday Marital Conflict and Child Aggression

Children's immediate aggressive responding to exposure to marital conflict was examined. Participants were 108 families with 8- to 16-year-old children (53 boys, 55 girls), with diary records of children's reactions to marital conflict in the home completed by 103 mothers (n = 578 records) and 95 fathers (n = 377 records) during a 15-day period. Child responses to analog presentations of marital conflict tactics were also obtained. Exposure to destructive conflict tactics and negative parental emotionality increased the likelihood of aggressive behavior in children when they witnessed marital conflict, whereas constructive conflict tactics and positive parental emotionality decreased the probability of aggression. Conflict topics presumed to be threatening to the child (child- or marital-related) also heightened the likelihood of aggression. Aggressive responding to conflict in both home and laboratory predicted externalizing behavior problems. Fathers' and mothers' separate diary reports, and child responses to analog presentation of conflict, provided generally consistent findings. An exposure hypothesis for marital conflict as an influence on child aggression is discussed.     

Conflict of interest in biomedical research: a view from Europe

In this paper I address the conflict of interest (CoI) issue from a legal point of view at a European level. We will see that the regulatory framework that exists in Europe does state the need for the independence of ethics committee involved in authorisation of research and clinical trials. We will see that CoI is an element that has to be closely monitored at National and International level. Therefore, Member States and Newly Associated States do have to address CoI in the authorisation process of research and clinical protocols of biomedicine. The opinions here expressed are personal and do not commit the European Commission. An earlier version of this paper was delivered at a Conference on Conflict of Interest and Its Significance in Science and Medicine, 5–6 April, 2002, Warsaw, Poland. The author is a Scientific Officer in the Programme Science and Society dealing with ethics and science (Unit C.3).     

Building blocks of self-control: increased tolerance for delay with bundled rewards

Impulsive choice can be defined as temporary preference for a smaller-sooner reward (SS) over a larger-later reward (LL). Hyperbolic discounting implies that impulsive choices will occur less when organisms choose between a series of SSs versus LLs all at once than when they choose between single SS versus LL pairs. Eight rats were exposed to two conditions of an intertemporal choice paradigm using sucrose solution as reward. In both conditions, the LL was 150 microl delayed by 3 s, while the SS was an immediate reward that ranged from 25-150 microl across sessions. Preference for the LL was greater when the chosen reward was automatically delivered three times in succession (bundled) than when it was chosen singly and delivered after each choice. For each of the 8 rats, the estimated SS amount that produced indifference was higher in the bundled condition than in the single condition. Because bundling in humans may be based on the perception that one's current choice is predictive of future choices, the data presented here may demonstrate an important building block of self-control.     

Group Identity and Conflicting Expectations of the Future in Northern Ireland

Much of the conflict in Northern Ireland is based on investments in one of three opposing political futures possible for the region: remaining part of Britain, joining Ireland, or becoming independent. Speculative scenarios describing each of these futures were randomly assigned to equal numbers of Protestant and Catholic undergraduates in Northern Ireland, and their expectations regarding material and civic improvement for their ingroup and peace and reconciliation between the groups were assessed. Two dimensions of religious identity, measured by the Identity and Public subscales of Luhtanen and Crocker's (1992) Collective Self-Esteem Scale (CSES), moderated the differences between groups, but only for their expectations of peace and reconciliation. Stronger expectations of improvement for the ingroup were related to higher scores on the Public subscale, regardless of religion or the political future presented. Thus, group identity had a complex, context-dependent relationship to intergroup conflict.     

Authoritarianism and PoliticalSocialization in the Context of the Arab-Israeli Conflict

This study explored the hypothesis that authoritarianism is negatively associated with peace supportiveness. A sample of 197 Jewish/Israeli university students responded to a questionnaire that included items on attitudes toward the Middle East peace process as well as a personality measure. The results confirmed the hypothesis: Individuals who were less supportive of the peace process were more authoritarian conformists than were supporters of the process. A significant association between religiosity and attitudes toward the peace process was also found; the split between peace supporters and non-supporters corresponded roughly, though not exactly, to the split between religious and non-religious. The pro-peace individual is generally non-religious, less authoritarian conformist, and less aggressive. Hence, the social cognitions studied—beliefs about the peace process—may be group beliefs. Certain characteristics of the groups in question, such as socialization practices and social structure, may account for the personality features that covaried with the beliefs. The data showing that peace attitudes, religiosity, and certain personality traits form one entity might thus be marshalled in discussing the identity issue and applied to other scenes in contemporary conflicts.     

Women and the Art of Peacemaking: Data from Israeli-Palestinian Interactive Problem-Solving Workshops

Are women “natural” peacemakers? If so, is this because of natural inclinations to avoid conflict or to engage in tough discussions? Are there particular skills in which women excel that make them more likely than their male counterparts to be able to build relational bridges, to facilitate negotiations, and to reduce tensions? After a review of the literature on gender differences in such skills, a systematic comparison of interaction quality is made between two Israeli-Palestinian interactive problem-solving workshops that differed only in gender composition. A third Israeli-Palestinian workshop that involved female political elites is also examined for subsequent changes in the conflict relationship or for changes in political activity. The implications of different repertoires of skills for altering political processes are discussed.     

Political Power and Race Relations in South Africa: African Attitudes Before and After the Transition

When an oppressed majority finally gains political power, what happens to its attitudes to its erstwhile oppressor, and to its perceptions and feelings about its socioeconomic disadvantages that were established during its oppression? Longitudinal data from pre- and post-transition surveys of black South African college and high school students indicate marked reductions in perceptions of and outrage about intergroup socioeconomic inequity and deprivation relative to English-speaking and Afrikaans-speaking whites, but no change in attitudes toward these groups or toward whites in general. The findings are discussed in terms of contemporary theory and research on justice, intergroup relations, and group conflict. Some tentative implications for the prospects for a democratic political culture in South Africa are noted.     

Ethical issues in graduate education

Concern about the employment prospects of Ph.D.’s in the sciences and engineering has prompted overdue interest in the ethical aspects of graduate education. It is not possible to isolate an ethical inquiry that focuses solely on job-related issues. The ethical problems in graduate education are each related to employment, but none is related to employment only. We can illuminate potential ethical problems by considering conflicts of interest at each point from the decision to offer a graduate program through the treatment of its alumni. Such consideration prompts reassessment of program content, relations with students, and the objectives of graduate programs. This paper is a revised and expanded version of a presentation given at the American Association for the Advancement of Science meeting in Seattle, WA, February, 1997, during a program organized by the National Science Foundation (“Ethics, Employment, and Graduate Education in Science and Engineering,” Rachelle Hollander, Organizer). Samuel Gorovitz is Professor of Philosophy and of Public Administration at Syracuse University.