Regional cerebral blood flow measurements by 133Xe-inhalation: Methodology and applications in neuropsychology and psychiatry

This review describes methodological improvements of the ¹³³Xe-inhalation technique for measurement of regional cerebral blood flow (rCBF) comprising correction routines both for scattered radiation from air passages and for remaining activity from previous measurements, as well as a new index of curve fit exactness. Measurements in normals are described showing new characteristics of the resting flow pattern and localized flow changes during activation with a variety of mental tasks. Our clinical applications in psychiatry are reviewed demonstrating the ability of the rCBF technique for differential diagnosis of dementia, for the evaluation of treatment by drugs, ECT, or psychosurgery, as well as for following, cases of toxic influence. The paper finally discusses the potentials as well as the limitations and artifacts of the technique.     

Cognitive restructuring treatment: A controlled trial with anxious patients

Cognitive restructuring, modified systematic desensitization and a combined treatment (cognitive behaviour modification) were compared with a no-treatment control group, using a simple randomized design. Twenty seven general anxiety out-patients selected from the hospital waiting list were used as subjects. Assessments were made at the beginning and end of treatment, and at follow-up 1 month later. The assessments included two subjective anxiety measures, the Zung self-rating anxiety scale and fear thermometer scores, a behavioural anxiety measure, a measure of cognitive anxiety as estimated by a diary recording of thinking time, fear survey schedule scores and I/E scores.Cognitive behaviour modification was found to be a superior form of treatment, relative to the no-treatment control and the other active treatment groups as assessed by FSS intensity score. The cognitive behaviour modification group showed greater improvement than the cognitive restructuring group on the diary anxiety scores. The results also demonstrated a relationship between outcome and initial severity of condition. The higher the subjects' initial scores on neurotic symptoms and subjective anxiety level, the greater the degree of positive change after treatment. Moreover, subjects with high levels of internal control prior to treatment responded most to therapy.     

Career development and career choice in pioneer and traditional women

Two groups of college seniors were compared in an attempt to elucidate those factors affecting feminine career choice and career development. The sample consisted of 106 female Caucasian students enrolled at a large Southwestern university. Sixty-three of the subjects were majoring in traditional female fields, while the remaining 43 were majoring in male-dominated areas. Five instruments were administered to the subjects. Seven factors were found to distinguish significantly between the two groups of women. Of the seven, three factors pertained to feminine role perception. The remaining four were concerned with sex-role stereotyping and various aspects of family background.     

Regional blood flow changes in the left cerebral hemisphere during word pair learning and recall

Regional cerebral blood flow measurements were made in the left hemisphere of 11 young healthy volunteers during learning and during recalling of word pair associates. Compared to the resting baseline, both tasks caused significant increases of average hemispheric flow, indicating an elevated neuronal activity level. Regionally both tasks were accompanied by considerable activation of parietal and occipital regions. The main difference between learning and recalling was that only the former task activated the prefrontal regions.     

Speech abnormalities in seizures: a comparison of absence and partial complex seizures

In order to determine whether speech changes are useful in differentiating seizure types, a study was done in which speech abnormalities during two distinct seizure types, partial complex and absence seizures, were compared. Speech changes noted during prolonged electroencephalographic and video monitoring were compared in 16 patients with 47 partial complex seizures and 19 patients with 95 absence seizures. Speech changes were common during both seizure types. Although some significant differences in speech patterns were noted in the two seizure types, the degree of overlap was such to preclude using speech changes alone as the sole clinical criteria in differentiating the seizures.     

A correlational study of stutterers' adaptation and voice initiation times

The purpose of this study was to determine the strength of the relationship, if any, between stutterers' amount of improvement in controlling phonation (voice initiation time) and their amount of improvement in stuttering during adaptation.Thirteen adult stutterers were required to participate in an adaptation task and a voice initiation time (VIT) task. The major finding was a weak, positive correlation between subjects' adaptation and their VIT difference scores. The correlation obtained, though weak, was interpreted to be informative; namely that while there is quite probably a laryngeal component in stuttering, it does not stand alone. It seems likely that the complexities of stuttering will not be fully understood until experiments include a number of potential or known dimensions of the disorder.     

中国早期放射科的建制化初探——以北大医院放射科为例

基于文献回溯与口述访谈,勾勒了北京大学第一医院放射科从1922年建科到1980年中期的发展历程.通过回顾该科室人事变迁、设备更新、科研及学术活动各方面的演进,展现了人-机依赖型临床医学科室的建制化路径及放射学技术的发展特色,反映了科室的技术价值积淀.     

Des psychologues en milieu hospitalier lors de la crise sanitaire de la Covid-19 : mieux comprendre leur vécu à l’aide du concept de générativité

IntroductionDuring the COVID-19 pandemic, everyone was confronted with their finitude, risking a crisis of meaning. Considering with Erikson (1950) that generativity is a great vector of meaning in life, which allows an individual to ensure the continuity of society through transmission and care, caregivers usually have a higher generativity score than the general population (Grossman & Gruenewald, 2017). This study then looks for signs of generativity among caregivers, hypothesising that it was particularly mobilised during this health crisis.PurposeThe purpose of this study is to explore the experiences of psychologists working in hospitals on somatic wards in order to identify the impacts of the COVID-19 pandemic and signs of generativity.MethodIn this exploratory, qualitative, prospective, multicenter study, nine psychologists working in hospital wards were interviewed individually to explore their experiences during a semi-structured interview.ResultsThe markers of existential crisis linked to COVID-19, such as signs of exhaustion and anxiety, were prominent in their discourse. Strong elements of generativity are also found in the interviews. This reflects the testing of their resources.ConclusionGenerativity allowed adaptation during the crisis but does not seem to be sufficient to protect against exhaustion and existential crisis.