炎症性肠病对育龄女性的影响及对策

炎症性肠病（IBD）临床表现为反复的黏液脓血便、腹痛、腹泻,甚至出现全身并发症。近年来其发病率呈逐年上升趋势。女性患者遗传给后代的几率高于男性患者,重症炎症性肠病往往需要手术治疗,影响女性患者的生育力,女性患者在妊娠、分娩期常常出现IBD活动或暴发加剧,使患者病情复杂化,严重影响育龄女性的身体健康。如何正确处理育龄女性IBD患者关系其生育力和妊娠、分娩安全以及胎儿安全。本文将从IBD对育龄女性生育力、妊娠、分娩、哺乳及胎儿的影响等方面进行综述,以帮助育龄女性IBD患者应对生育问题。     

Are summary statistics enough? Evidence for the importance of shape in guiding visual search

Peripheral vision outside the focus of attention may rely on summary statistics. We used a gaze-contingent paradigm to directly test this assumption by asking whether search performance differed between targets and statistically-matched visualizations of the same targets. Four-object search displays included one statistically-matched object that was replaced by an unaltered version of the object during the first eye movement. Targets were designated by previews, which were never altered. Two types of statistically-matched objects were tested: One that maintained global shape and one that did not. Differences in guidance were found between targets and statistically-matched objects when shape was not preserved, suggesting that they were not informationally equivalent. Responses were also slower after target fixation when shape was not preserved, suggesting an extrafoveal processing of the target that again used shape information. We conclude that summary statistics must include some global shape information to approximate the peripheral information used during search.     

The role of learning and career guidance for managing mid-career transitions – comparing Germany and Denmark

In Germany and Denmark, the systems of further education and career guidance are well developed, offering a wide range of services and learning opportunities for targeted, specific and also general skills development. Based on an empirical study with mid-career individuals in both countries, the article investigates how the different systems support individuals to manage a career transition and develop their individual pathways. Mid-career transitions can be considered particularly challenging as they often reflect a more profound crisis and major concerns about future career opportunities. Constraints that prevent individuals in mid-career to fully benefit from the learning and guidance offers available can be identified in both countries. These range from the availability of programmes and accessing funding to getting the ‘right’ information. These constraints partly derive from adult education and guidance systems presupposing linear careers rather than disruptive trajectories and horizontal mobility.     

Guidance systems across Europe: heritage,change and the art of becoming

Guidance systems exist within learning, working and welfare cultures, which are upheld by prevailing institutions and stakeholders. Implementing a lifelong approach questions rooted codes and idiosyncrasies of the sectors across which guidance is distributed. To support individuals' careers, unlock their potential and increase their contribution to the economy i.e. support their process of becoming, lifelong guidance must strive for effective systems' integration across policy fields, cultures and organisations. This article departs from national experiences and discusses how cultures and institutional contexts generate resistance to change, but can also be the departure point for the successful development of lifelong support to people's careers.     

Testing times: careers market policies and practices in England and the Netherlands

Careers work is a very political business. Since the early 1990s, successive governments in England and the Netherlands have persistently challenged those working in the careers sector to demonstrate the educational, social and economic value and impact of their work. In this context, the marketisation of career guidance policies and practices has expanded, with a growing assumption that market-based goods and services ensure greater responsiveness to consumer choice and offer better and/or more innovative services for lower prices. In this article, we do not intend to give a comparison of trends in England and the Netherlands. We only examine the impact of market principles applied to career guidance provision in both countries. Findings indicate such provision for young people is on a steady decline. Lessons learned from these two nations indicate that a market for quality career services does not exist in schools and colleges. As a result, marketisation and privatisation of career services have led to an impoverished and fragmented supply of services. Greater attention by governments in career guidance policies for young people (and adults) is necessary to reduce the widening gap between ‘the haves and have nots’ in society. Failure to reduce labour market mismatch through new forms of careers dialogue is not only damaging and costly for individuals, families and employers, but for the taxpayer too.     

Academic promises and family (dis)enchantments: clues for guidance and counselling in higher education

Family has an undeniable influence upon the career construction of higher education (HE) students, since it is a primary source of their socialisation. This article presents a qualitative analysis of 30 interviews conducted with first-year students, aimed at understanding the relationship between family sociocultural status and career choice and the perceived meaning in the family of the enrolment of one of their elements in HE. Results show that HE students came mainly from economic, cultural and social upper classes. It was a ‘logic path’, for who would inherit in the adult age, not only the economic capital, but also the relational capital. The educational and economic resources of the students' families are key factors in the choice to pursue HE studies, rather than the professional world.     

基于双眼视差探讨深度知觉信息对背景线索效应的影响

背景线索效应是由重复场景导致搜索效率提高的现象。以往研究发现三维场景下能获得背景线索效应,但对三维场景下深度知觉线索信息如何影响空间场景提供有效线索引导注意仍缺乏实证研究。本研究以矩阵刺激为材料,通过设置不同的刺激项目水平数探讨深度知觉线索对背景线索效应的影响模式。结果发现:(1)在场景布局由较少项目构成时,深度知觉线索提供目标与刺激项目的有效联结,获得背景线索效应;(2)当刺激项目水平达到一定程度时,深度知觉线索增加了背景线索任务的搜索难度,干扰了重复场景中的背景信息对注意的指导性加工,背景线索效应消失。研究结果为三维场景下深度信息对空间场景中注意引导加工的影响提供了证据。     

Ensuring an independent future for young people with special educational needs and disabilities (SEND): a critical examination of the impact of education,health and care plans in England

This article examines the implications of the new education, health and care (EHC) planning process for career professionals in England. The new process comes in the wake of a succession of legislation relating to young people with special educational needs and disabilities (SEND) in England. There is much to recommend the new process as it represents a shift to a more holistic and person-centred approach. However, there are four main criticisms which can be made of the new process: (1) the policy has an excessive focus on paid work as an outcome which is unrealistic (for some young people); (2) the resourcing in local authorities is too limited to successfully operationalise the policy; (3) there is a lack of clarity about the professional base delivering EHC planning (especially in relation to the career elements); and (4) the policy is too narrowly targeted. While the new legislation offers some major opportunities, realising these will be difficult. In this paper, questions are raised about the resources required to deliver these services; the responsibilities relevant to such services; and the role and scope of these services in supporting the transitions of vulnerable young people into learning and work in an environment where universal careers provision has been substantially diminished.     

Advising on career image: perspectives,practice and politics

This article analyses qualitative data gathered from a survey of career practitioners on the issue of career image (n?=?355, 75% female, 89% white and 78% from the UK). Findings reveal three key themes which represent how career image relates to practitioners’ values and beliefs, how practitioners make decisions about whether to address the topic in their practice and the strategies they use to address career image with their clients. Findings are discussed with reference to Watts’s socio-political ideologies of guidance. The data indicate that career practitioners are often uncomfortable about discussing career image, but address it where they believe that it is important to their clients’ success. While some practitioners believe the existing structures to be unjust, they generally seek to address this injustice at the individual level rather than seeking any kind of social transformation.     

Does Semantics Need Normativity? Comments on Allan Gibbard,Meaning and Normativity

In the book Gibbard proposes, first, that statements about meaning are normative statements and, second, that they can be given an expressivist treatment, along the lines of Gibbard’s preferred metaethics. In my paper, I examine the first step: The claim that meaning statements are to be construed as being normative, as involving ‘oughts’. Gibbard distinguishes two versions of the normativity of meaning thesis – a weak version, according to which every means implies an ought, and a strong version, according to which for every means, there is an ought that implies it. I argue that neither thesis withstands scrutiny. The weak thesis depends on assumptions about the notion of semantic correctness that the anti-normativist rejects, and the strong thesis does not solve the problems Gibbard wants it to solve: the problems of indeterminacy and meaning skepticism. I conclude that semantics does not need normativity.