Private-Sector Research Ethics: Marketing or Good Conflicts Management? The 2005 John J. Conley Lecture on Medical Ethics

Pharmaceutical companies are major sponsors of biomedical research. Most scholars and policymakers focus their attention on government and academic oversight activities, however. In this article, I consider the role of pharmaceutical companies’ internal ethics statements in guiding decisions about corporate research and development (R&D). I review materials from drug company websites and contributions from the business and medical ethics literature that address ethical responsibilities of businesses in general and pharmaceutical companies in particular. I discuss positive and negative uses of pharmaceutical companies’ ethics materials and describe shortcomings in the companies’ existing ethics programs. To guide employees and reassure outsiders, companies must add rigor, independence, and transparency to their R&D ethics programs.     

Justice to Nature and to the Disadvantaged

This article argues against using the practice of discounting and shows that both the time preference and the opportunity cost of capital arguments, put forward to justify discounting, are in conflict when we take the holistic approach to the environment. Both the time preference and the opportunity cost concepts are the tools to support the institution of interest. Using a hierarchical systems approach it is argued that in order to save the super hierarchical system (biosphere as a whole in our case) the contemporary economic system has to renew so that the humanity and global ecosystem may persist.     

Constructs,inferences, and mental measurement

The ‘construct’ concept occupies a significant place in psychology and, yet its role is misunderstood. Psychologists think that theorising in the area of psychological testing involves conjuring constructs, which are operationally defined and measured via psychometric tests. However, the ‘construct’ concept is unworkable and laden with confused philosophical baggage accrued under the hegemony of logical empiricism, and its real function in psychology is obscured. Via an analysis of its history and logic, I expose its flawed conception of the relation between theoretical and observable concepts and the way in which it serves the myth of mental measurement. Finally, it is shown how the actual logic of theorising in science, which entails that theories are best inferred from relevant phenomena, not imaginatively constructed, oppugns this myth and promises to coordinate theoretical concepts with the phenomena to be explained.     

A psychobiographical analysis of Dambudzo Marechera's personal development through his writings

This study applied psychobiography to explore the personal development of Zimbabwean novelist Dambudzo Marechera – and particularly focus on psychological disintegration. For the evidence, we examined primary and secondary works on his life history with special attention to his literary works. Findings indicate that his early writings were autobiographical in nature, chronicling lived poverty, war and violence experiences. Later writings were somehow surrealistic and unstructured, marking a culmination of significant personal disintegration that started in early childhood. Other ancillary biographical evidence suggests self-perceptions as a cult-like figure, and what appears to be a limited social interest.     

The Imperatives of Narrative: Health Interest Groups and Morality in Network News

This article examines some of the story conventions of network television news to explain the ways in which healthcare interest groups develop and maintain their presence in this medium—a process that has significant implications for public understanding of healthcare issues, and therefore to bioethics. The article is divided into three sections. The first section focuses on three major normative conventions of television news: adherence to a simple narrative structure, the balance ethic, and avoidance of the “think-piece” and outlines the basic strategies available to interest groups for exploiting these normative conventions. Section two introduces three case studies of organizations and individuals who have run high-profile media campaigns. Section three explores the implications for bioethics of the observations made in this article.     

Do lesbian women have a better body image? Comparisons with heterosexual women and model of lesbian-specific factors

Body dissatisfaction is prevalent among women but may be less common among lesbian women. Although research trends toward this conclusion when samples are well-matched and body mass index (BMI) is controlled for, many studies do not exhibit these characteristics. Furthermore, few studies have examined sociocultural contributors to group differences. I addressed limitations of past research with a large community sample of lesbian (n = 479) and heterosexual (n = 400) women. I contrasted the two sexual identity groups on several body dissatisfaction measures, and tested theoretically derived relationships between lesbian-specific cultural factors and body dissatisfaction. As predicted, lesbian women reported lower body dissatisfaction than did heterosexual women on three of four measures, and expressed a larger ideal body size. A structural equation model of lesbian-specific risk and protective factors for body dissatisfaction did not reveal significant relationships. This study represents a first attempt to model culturally specific influences on lesbian body image.     

Curiosity and well-being

Recent conceptualizations of curiosity have identified two underlying factors that together represent trait curiosity: exploration (the disposition to seek out novel/challenging situations) and absorption (the disposition to become fully engaged in these interesting situations) (Kashdan, Rose, & Fincham, 2004). These factors have been proposed to broaden the thought–action repertoire by promoting interest in novel/challenging situations and to incrementally build knowledge and well-being in a manner consistent with the Broaden-and-Build Theory (Fredrickson, B. L., 1998). This article reports findings from a study which examined associations between the exploration and absorption components of curiosity and continuous and categorical indices of well-being. Replicating and extending previous findings, the exploration (more so than absorption) component of curiosity exhibited moderate positive associations with measures of well-being. Implications and suggestions for future research are discussed.     

Authoritarianism and Political Impoverishment: Deficits in Knowledge and Civic Disinterest

Past research shows that authoritarian individuals hold strong opinions about a variety of political and social issues, such as race relations and military conflict. What has not been established, though, is the amount of general political knowledge that authoritarians possess. In this study, three groups of college students were administered Altemeyer's Right-Wing Authoritarianism (RWA) scale; most of them also received items assessing general political knowledge and specific knowledge about the 2000 presidential election, as well as items assessing interest in politics. Relative to students with low RWA scores, those with high scores possessed less political knowledge; moreover, they expressed less interest in learning about politics. In general, authoritarianism was unrelated to how individuals got their political information or how credible they found their sources. The implication that authoritarians hold strong attitudinal beliefs with weak political knowledge is discussed.     

论医院经济效益

医院增加医药收入是天经地义的,但不能在病人身上创造经济效益。通过对当前问题的剖析,提出在当前群众看病难的社会环境下,提高医院经济效益,兼顾病人利益的政策性建议。     

Nodule Detection with Eye Movements

Radiologists often miss nodules that may represent lung cancer on chest radiographs. We investigated whether eye movements collected during the search for lung nodules by large samples of laypeople may provide information that could assist radiologists in their detection. For that purpose, we developed a partially invisible Markov model with partially unobserved states and analyzed eye tracking data of over 100 laypeople who reviewed 14 chest X‐ray images, of which seven contained a potentially cancerous nodule. We used the luminance value of the pixels in the X‐ray images as prior information on the possible location of a nodule and identified six regions of interest on each image that may contain a nodule. Our study demonstrated that the eye movements recorded from laypersons contained information that may assist radiologists in the detection of nodules in chest X‐rays, which has important implications for crowdsourcing of search for pulmonary nodules, which are discussed. Copyright © 2016 John Wiley & Sons, Ltd.