Conflict of interest: the importance of potential

The UK Medical Research Council (MRC) takes the issue of conflict of interest very seriously. The overall aim is to preserve a climate in which personal and organisational innovation can flourish while ensuring that potential conflicts are disclosed and identified and conflicts are either avoided or managed with integrity. The approach needs to encompass the MRC’s various responsibilities and the levels at which conflicts might arise: MRC staff (scientists and administrators); the governing Council; research Boards and committees; external peer-reviewers; and applicants for funding. To achieve its goals, the MRC has issued practical guidance on various aspects of conflict of interest. For the future, the MRC has identified the continuing commercialisation of science and the increasing involvement of lay people in scientific decision-making as special challenges in this area. An earlier version of this paper was presented at an International Conference on “Conflict of Interest and its Significance in Science and Medicine” held in Warsaw, Poland on 5–6 April, 2002.     

Individual and institutional conflict of interest: policy review by research universities in the United States

This paper is a discussion of efforts to manage real and potential conflicts of interest in university research in the United States. The focus is on the report by an Association of American Universities (AAU) task force that addresses both individual and institutional conflict of interest issues. An earlier version of this paper was presented at an International Conference on “Conflict of Interest and its Significance in Science and Medicine” held in Warsaw, Poland on 5–6 April, 2002.     

Ethical issues at the university-industry interface: A way forward?

This paper forms an introduction to this issue, the contents of which arose directly or indirectly from a conference in May 2001 on Corruption of scientific integrity? — The commercialisation of academic science. The introduction, in recent decades, of business culture and values into universities and research institutions is incompatible with the openness which scientific and all academic pursuit traditionally require. It has given rise to a web of problems over intellectual property and conflict of interest which has even led to corporate sponsors’ suppressing unfavourable results of clinical trials, to the detriment of patients’ health. Although there are those who see the norms of science developing to recognise the importance of instrumental science aiming at specific goals and of knowledge judged by its value in a context of application, none justifies the covert manipulation of results by vested interest.Public awareness of these problems is growing and creating a climate of opinion where they may be addressed. We suggest a way forward by the introduction of nationally and internationally-accepted guidelines for industrial collaboration which contain proper protections of the core purposes of universities and of the independence of their research. Some codes suggested for this purpose are discussed. We note that some universities are moving to adopt such codes of conduct, but argue the need for strong support from the government through its funding bodies.     

Training the brain: fact and fad in cognitive and behavioral remediation

Putatively safe and effective for improving cognitive performance in both health and disease, products purported to train the brain appeal to consumers and healthcare practitioners. In an increasingly health-centered society, these applications constitute a burgeoning commercial market. Sparse evidence coupled with lack of scientific rigor, however, leaves claims concerning the impact and duration of such brain training largely unsubstantiated. On the other hand, at least some scientific findings seem to support the effectiveness and sustainability of training for higher brain functions such as attention and working memory. In the present paper we provide a tectonic integration and synthesis of cognitive training approaches. Specifically, we sketch the relative merits and shortcomings of these programs, which often appeal to parents who must choose between side-effect-laden medication and other less conventional options. Here we examine how neuroplasticity allows the healthy as well the impaired to benefit from cognitive training programs. We evaluate the evidence and consider whether brain training can be a stand-alone treatment or an adjunct to pharmacotherapy, outline promising future prospects, and highlight what training outcomes are plausible in line with available data. Future research would determine whether the field of brain training realizes its potential to revolutionize education and rehabilitation or withers away engulfed in controversy.     

Relation of occupational knowledge to career interests and competence perceptions in Italian children

The relations of differential occupational knowledge with interests and competence perceptions in children as well as how these relations were moderated by gender and grade were examined in this study using an Italian sample. Data were collected from samples of elementary school and middle school children (N = 539). The Inventory of Children's Activities—Revised (ICA-R; Tracey & Ward, 1998) was used to assess children's interest and competency perceptions in various activities associated with the Holland's RIASEC types. The Occupational Knowledge Scale (OKS) was created for this study, and consisted of a representative sampling of occupational titles to which children indicated their knowledge. Hierarchical regression results indicated a relationship between knowledge, interests, and competence perceptions in children. With regard to overall knowledge, no relationship was found between general knowledge and either grade or gender. More specific examination of the type of knowledge as it varied across the dimensions of People–Things, and Data–Ideas demonstrated that there appeared to be a specific pattern relating interest, gender, and grade to knowledge of occupations. For knowledge of people relative to things occupations, higher interest, higher grade level, and being female predicts stronger knowledge of people occupations. It was also found that interest in ideas predicts stronger knowledge of ideas occupations, and being male predicts stronger knowledge of high prestige occupations. Generally, competence perceptions did not have a unique relation with one's knowledge of People–Things, Ideas–Data, or Prestige; however, girls who reported higher competence had greater knowledge of ideas occupations.     

Behavioral science integration: A practical framework of multi-level converging evidence for behavioral science theories

Several frameworks exist to help science in organizing known information, connecting previously disparate phenomena, promoting understanding, and identifying gaps in knowledge. This paper integrates previous frameworks that have been used in the behavioral sciences to produce a more comprehensive, specific, and complete framework, consonant with the process of scientific discovery as based on multiple, independent, and converging lines of evidence. This multi-level convergence framework is designed specifically for the analysis and understanding of human cognitive/behavioral traits, in contrast to more general frameworks that are designed to be applied relatively widely (such as across all information processing systems or across all biological organisms). This integrated framework overcomes gaps in prior frameworks, provides a more complete picture of the interrelationships between various aspects of the behavioral sciences, and can aid in evaluating theories, both for comparison and identifying gaps in evidentiary support.     

The “impact factor style of thinking”: A new theoretical framework

Over the last few years, university policy in developed countries has placed too much emphasis on assessing publications on the basis of the impact factor. Any scientific material that has not been published in a journal indexed in the Journal Citation Reports is academically irrelevant. Hence, researchers strive hard to publish in such journals. Failure to achieve this means not having a successful career or receiving any academic recognition. A thorough analysis of the effects of this phenomenon on the researcher community leads to the conclusion that the overestimation of the impact factor is likely to cause disappointment among many researchers. Researchers only have two options: adopting a politically correct behavior, that is, following the “impact factor style of thinking”, or accepting the futility of their research regardless of its relevance. This is an example of the involvement of university policy habitus obsessed impact index. O policy impact index is accepted, or is doomed to academic ostracism, and exclusion from participation in all university policy.     

Thinking bigger: The Cronbachian paradigm & personality theory integration

Personality theories largely mirror disparities between fundamental paradigms that guide most psychology: one based upon Galton’s emphasis on inter-individual differences and the lexical hypothesis; the other inspired by Wundt is focused upon intra-individual processes, such as temperament and Reinforcement Sensitivity Theory. Previous integrations of personality models using these paradigms failed to account for observed variance, suggesting model incommensurability. We propose that a broader conception—developed from Cronbach and colleagues’ generalisability theory—provides an effective integrating framework, and show how Galtonian and Wundtian models may be assimilated within Cronbachian approaches. Additionally, Cronbachian models have novel practical implications. Application of the Cronbachian paradigm to personality will be challenging, but provides an opportunity to achieve genuine coherence in personality research.     

Gender differences in STEM undergraduates' vocational interests: People–thing orientation and goal affordances

This study addressed why women have greater representation in some STEM (science, technology, engineering, and mathematics) fields compared to others by linking two theoretical approaches, people–thing orientation (PO, TO) and role congruity theory, which emphasizes occupation goal affordances associated with traditionally feminine and masculine roles. Vocational interest and goal affordance ratings (having a positive social impact, family, and occupation status) for occupations characterized as working with people or things were assessed in 1848 students (42% female; 81% white non-Hispanic) majoring in biology (gender balanced), non-biology STEM (male-dominated), and female-dominated health fields. Participant PO and TO interests were also collected. Results indicated that non-biology STEM majors showed lower PO and higher TO interests than biology and health majors. Non-biology STEM majors also endorsed PO and TO interests at similar levels, but the other two major groups indicated higher PO than TO. People Jobs were perceived to more likely afford goals related to family and positive social impact; whereas Thing Jobs were perceived to more likely afford status goals. Interest in People Jobs was similar for women in both STEM major groups. Female non-biology STEM majors were equally interested in People and Thing Jobs; whereas biology majors preferred People Jobs. PO, TO, and goal affordance ratings independently predicted interest in People and Thing Jobs, and gender accounted for very little additional variance. Taken together, the findings point to the importance of using both person–thing orientation and role congruity theory when explaining varied gender representations in different STEM fields.