Contribution of temporal preparation and processing speed to simple reaction time in persons with Alzheimer’s disease and mild cognitive impairment

Temporal preparation was assessed in 15 Alzheimer’s disease (AD) patients, 20 persons with mild cognitive impairment (MCI) and 28 healthy older adults. Participants completed a simple reaction time task in which the preparatory interval duration varied randomly within two blocks (short versus long temporal window). Results indicated that AD and MCI patients had difficulty preparing for the shortest preparatory interval of the short temporal window. AD and MCI patients also had difficulty maintaining an optimal level of preparation up to 5 s within the short temporal window. These results suggest that AD and MCI patients might show difficulty preparing for rapidly occurring events and maintaining preparation over time. This phenomenon should be considered when using reaction time measures with such patients.     

时序表征的空间特性

时间是个高度抽象的概念,必须依靠具体的、易感知的事物进行表征。时间表征本质上是隐喻性的,而时间的空间隐喻是时间隐喻表征的原型。受到数字空间表征研究的启示,发现时序表征同样具有空间特性。时序表征具有空间特性具有一定的普遍性,但是在具体的水平或垂直空间维度、“左-右”或“右-左”空间方向上存在一定的灵活性;此外时序能够导致空间注意的转移。     

前瞻记忆的神经机制：来自临床研究的证据

前瞻记忆是指对预定事件或行为的记忆。本文总结了前瞻记忆脑机制相关的文献,介绍了前额皮层、丘脑,内侧颞叶等脑区域在前瞻记忆中的作用,并通过分析注意缺陷多动障碍儿童、老年痴呆症患者、酒精依赖症和内侧颞叶癫痫患者前瞻记忆的表现,从临床角度深入探讨了前瞻记忆神经机制的问题。证据表明,前额皮层参与前瞻记忆的编码、提取和监控过程,与意向保持也有密切的关系;丘脑与意向的执行有关,并且与前额叶互动在前瞻记忆监控中起着重要的作用;内侧颞叶与编码来源的提取和意向的激活都有密切的关系。研究认为前额皮层在前瞻记忆加工过程中起着核心的作用,同时与丘脑、内侧颞叶等区域相互作用,共同成为前瞻记忆编码、保持、提取、执行的神经基础。     

Disentangling perceptual and motor components in inhibition of return

Following an abrupt onset of a peripheral stimulus (a cue), the response to a visual target is faster when the target appears at the cued position than when it appears at other positions. However, if the stimulus onset asynchrony (SOA) is longer than approximately 300 ms, the response to the target is slower at the cued position than that at other positions. This phenomenon of a longer response time to cued targets is called "inhibition of return" (IOR). Previous hypotheses propose contributions of both response inhibition and attentional inhibition at cued position to IOR, and suggest that responding to the cue can eliminate the component of response inhibition. The current study uses tasks either executing or withholding response to the cue to investigate the relative contributions of response and attention components to IOR. A condition with bilateral display of the cue is also chosen as a control condition, and eight different SOAs between 1,000 and 2,750 ms are tested. Compared to the control condition, response delay to the target at a cued position is eliminated by responding to the cue, and a response advantage to the target at an uncued position is not affected by responding to the cue. Furthermore, both response delay at a cued position and response advantage at an uncued position decrease with SOA in the time window tested in these experiments. The results reported here indicate a dominant response inhibition at a cued position and a primary attentional allocation at an uncued position for IOR. Nonsignificant perceptual/attentional suppression at a cued position is argued to be a benefit for visual detection in a changing world.     

Effects of message framing and temporal context on college student drinking behavior

This study evaluated the interactive effects of message framing and temporal context on college student alcohol use. Participants (n = 228) were randomly assigned to read an alcohol prevention message that varied by message frame (gains vs. losses) and temporal context (short- vs. long-term consequences). Participants returned to the lab one month later to report their drinking behavior over the past month. As predicted, students exposed to the gain-framed message reported lower alcohol use (drank less frequently, drank fewer alcoholic beverages per drinking occasion, and engaged in less binge drinking) as compared to students exposed to the loss-framed message, but only if they read about short-term consequences of alcohol use. Message frame had no effect when participants were exposed to long-term consequences. This investigation extends previous research by demonstrating the effectiveness of message framing for reducing health-damaging behaviors and by identifying temporal context as a moderator of framing effects.     

Seeing oneself in one’s choices: Construal level and self-pertinence of electoral and consumer decisions

Building on previous research examining the implications for self-regulation and decision making of construing action at varying levels of abstraction, the authors proposed that construing action in terms of its abstract purposes facilitates orienting one’s decisions toward the standards, characteristics, and goals that define one’s desired self-concept. Consistent with this proposal, desiring for oneself a political candidate’s personal qualities predicted evaluating favorably (in Study 1) and voting for (in Study 2) that candidate to a greater extent among participants focused on the distal future (and presumably construing action at a relatively high-level of abstraction) than the proximal future (and presumably construing action at a relatively low-level of abstraction). Moreover, individuals chronically construing action in high-level terms responded more favorably to advertisements appealing to their desired self-concept (in Study 3) than to product quality. These findings’ implications for decision making are discussed.     

Nonuniform effects of reinstatement within the time window

A time window is a limited period after an event initially occurs in which additional information can be integrated with the memory of that event. It shuts when the memory is forgotten. The time window hypothesis holds that the impact of a manipulation at different points within the time window is nonuniform. In two operant conditioning experiments with 68 3-month-old human infants, we tested the predictive validity of the nonuniformity principle for reinstatement—a partial training trial that forestalls forgetting. After demonstrating that 3-month-olds forget the training task after 5 days (Experiment 1), we presented a reinstatement early (immediately), midway (3 days), or late (5 days) in the time window (Experiment 2). Retention increased exponentially with the reinstatement delay. The surprising magnitude of this result, plus its generality across tasks and species, strongly suggests that the timing of reinstatement differentially affects the outcomes of studies on learning and memory.     

How to, and how not to, bridge computational cognitive neuroscience and Husserlian phenomenology of time consciousness

A number of recent attempts to bridge Husserlian phenomenology of time consciousness and contemporary tools and results from cognitive science or computational neuroscience are described and critiqued. An alternate proposal is outlined that lacks the weaknesses of existing accounts.     

An Impossibility Theorem on Beliefs in Games

A paradox of self-reference in beliefs in games is identified, which yields a game-theoretic impossibility theorem akin to Russell’s Paradox. An informal version of the paradox is that the following configuration of beliefs is impossible:Ann believes that Bob assumes thatAnn believes that Bob’s assumption is wrongThis is formalized to show that any belief model of a certain kind must have a ‘hole.’ An interpretation of the result is that if the analyst’s tools are available to the players in a game, then there are statements that the players can think about but cannot assume. Connections are made to some questions in the foundations of game theory.Special Issue Ways of Worlds II. On Possible Worlds and Related Notions Edited by Vincent F. Hendricks and Stig Andur Pedersen