Effect of exposure to lithium-paired or amphetamine-paired saccharin solution on open arm avoidance in an elevated plus maze

Recent evidence suggests that drug-induced conditioned taste avoidance may be mediated by conditioned fear (e.g., Parker, 2003). The experiments reported here evaluated the effect of exposure to a drug-paired flavor on open arm exploration in an elevated plus maze (EPM), a measure of fear. When rats were tested on a familiar (trial 2) EPM, but not on a novel (trial 1) EPM, prior exposure to a lithium-paired saccharin solution enhanced open arm activity relative to saline-paired saccharin. On the other hand, when rats were exposed to lithium-paired saccharin during plus maze exposure, they displayed suppressed open arm activity relative to unpaired controls when tested in a familiar maze. The pattern of results was specific to the conditional affective properties of the taste, because exposure to unconditional sickness produced by administration of lithium, and unconditionally unpalatable quinine solution did not produce this pattern. These results were interpreted in terms of the opponent process model of motivation; that is, exposure to a lithium-paired flavor elicits conditioned fear which is immediately followed by conditioned relief when the exposure is terminated. On the other hand, exposure to an amphetamine-paired flavor either before or during EPM testing enhanced open arm exploration. Since the strength of taste avoidance did not differ among amphetamine and lithium conditioned rats, these results provide further evidence that the nature of a saccharin-lithium association differs from that of a saccharin-amphetamine association.     

Burying by rats in response to aversive and nonaversive stimuli

Previous investigations have shown that rats bury a variety of conditioned and unconditioned aversive stimuli. Such burying has been considered as a species-typical defensive reaction. In the present studies, rats buried spouts filled with Tabasco sauce, or condensed milk to which a taste aversion was conditioned, but did not bury water-filled spouts or spouts filled with a palatable novel food (apple juice) to which a taste aversion was not conditioned. However, in other experiments rats consistently and repeatedly buried Purina Rat Chow, Purina Rat Chow coated with quinine, and glass marbles. This indicates that a variety of stimuli, not all aversive or novel, evoke burying by rats. Whereas the behavior may reasonably be considered as a species-typical defensive behavior in some situations, the wide range of conditions that occasion burying suggests that the behavior has no single biological function.     

Predicting the intensity of losses vs. non-gains and non-losses vs. gains in judging fairness and value: A test of the loss aversion explanation

Three studies examined the predictions that in the context of evaluation of fairness and concessions in negotiations, losses would be perceived as more intensely negative than non-gains, and that non-losses would be perceived as more positive than gains. Extant studies tested only the first of these predictions. These predictions derive from the principle of loss aversion (LA), according to which losses are experienced more intensely than gains of similar objective magnitude. In this view, losses and non-losses are measured against the steep loss part of the value curve, whereas gains and non-gains are measured against the shallow part of the value curve. Our studies replicated extant studies in confirming the first prediction but failed to confirm the second prediction. Specifically, opposite to the prediction of LA, gains were perceived as more intensely positive than non-losses. It seems, therefore, that LA is not a sufficient explanation of why losses are perceived as more averse than gains. Feature positive and regulatory focus effects are discussed as additional potential contributors to the phenomenon.     

以兔抗鼠淋巴细胞血清为非条件刺激的条件性免疫抑制

采用一种生物类免疫抑制剂-兔抗鼠淋巴血清（rabbit anti-rat lymphocyte serum,ALS）为非条件刺激（UCS）,糖精水为条件刺激（CS）,以双瓶给水法置于鼠笼前端饮用偏好侧。在一次性CS-UCS结合训练后,单独再次给予CS,使卵清蛋白（OVA）免疫过的大鼠表现出脾淋巴细胞对有丝分裂原PWM的增殖反应降低,血抗OVA抗体的总量及脾内抗OVA抗体生成细胞的减少,但动物未表现出条件性味觉厌恶的行为反应。这些结果表明条件性免疫抑制与味觉厌恶行为条件反射没有必然联系,并非是厌恶行为反应或情绪应激的伴随产物。UCS也并非必需具有感觉的毒副作用,条件性免疫抑制是脑高级神经活动调节免疫功能的结果。     

模糊规避的形成机制：基于可评价性假设的视角

模糊规避是指在相同奖赏的情况下,决策者会力图规避从主观上判断具有模糊概率的事件而偏好具有相同精确概率的事件。本研究使用同时评价、单独评价的研究范式从随机事件和自然事件两个领域来探讨模糊规避的形成机制。研究结果表明,当风险事件和模糊事件同时评价时,个体倾向于模糊规避;当风险事件和模糊事件单独评价时,模糊规避会消失。     

行为决策中的默认效应

默认效应指的是当存在默认选项时, 人们决策时倾向于保留默认选项而不做出改变的一种现象。这种现象广泛存在于器官捐献政策、退休金储蓄计划和消费决策等领域并在这些领域中有巨大的应用价值。目前, 研究者主要从损失规避、质询理论、暗含的推荐和神经心理机制四个方面解释默认效应的形成机制。默认效应还受到努力成本、默认选项的框架和个人经验等因素影响。未来的研究可以从深入探讨默认效应的产生根源、加强其跨文化研究以及拓展其应用领域这三个方面来展开。     

Reference dependence in iterative choices

Valuation of goods often proceeds from a series of hypothetical pairwise choices. We examine reference dependence on the outcome of such evaluations in a large-scale study in which respondents make a series of choices between areas that differ on cost of living and the quality of lakes and rivers. We uncover three substantial reference effects. First, we find that respondents’ choices are altered by being told the national value of water quality. For these people, consistent with prospect theory, changes in water quality below the 65% referenced national standard are treated as losses and given more weight while identical changes above 65% are treated as gains and given less weight. Second, we find that the sequence of iterative choices matters in a surprising way. The iterations proceed by encouraging switching either by degrading the chosen alternative or improving the item chosen. We show that improving the item not chosen produces the greatest switching, a result consistent with prospect theory, but only if the item changed in the iteration becomes the reference alternative. Finally, we find a strong starting reference effect. That is, we show that the trade-off in the first choice reflected in the change in cost of living divided by the change in water quality has a substantial impact on the final valuation. We assess the relative impact of these three reference effects and suggest ways of dealing with them for valuation of non-market goods.     

Explicit disassociation of a conditioned stimulus and unconditioned stimulus during extinction training reduces both time to asymptotic extinction and spontaneous recovery of a conditioned taste aversion

Conditioned taste aversions (CTAs) may be acquired when an animal consumes a novel taste (CS) and then experiences the symptoms of poisoning (US). This aversion may be extinguished by repeated exposure to the CS alone. However, following a latency period in which the CS is not presented, the CTA will spontaneously recover (SR). In the current study we employed an explicitly unpaired extinction procedure (EU-EXT) to determine if it could thwart SR of a CTA. Sprague-Dawley rats acquired a strong CTA after three pairings of saccharin (SAC the CS) and Lithium Chloride (LiCl the US). CTA acquisition was followed by extinction (EXT) training consisting of either (a) CS-only exposure (CSO) or (b) exposure to saccharin and Lithium Chloride on alternate days (i.e., explicitly unpaired: EU). Both extinction procedures resulted in ?90% reacceptance of SAC, although the EU extinction procedure (EU-EXT) significantly decreased the time necessary for rats to reach this criterion (compared to CSO controls). Rats were subsequently tested for SR of the CTA upon re-exposure to SAC following a 30-day latency period of water drinking. Rats that acquired a CTA and then underwent the CSO extinction procedure exhibited a significant suppression of SAC drinking during the SR test (as compared to their SAC drinking at the end of extinction). However, animals in the EU-EXT group did not show such suppression in drinking compared to CSO controls. These data suggest that the EU-EXT procedure may be useful in reducing both time to extinction and the spontaneous recovery of fears.     

The evidence for relativism

The aim of this paper is to examine the kind of evidence that might be adduced in support of relativist semantics of a kind that have recently been proposed for predicates of personal taste, for epistemic modals, for knowledge attributions and for other cases. I shall concentrate on the case of taste predicates, but what I have to say is easily transposed to the other cases just mentioned. I shall begin by considering in general the question of what kind of evidence can be offered in favour of some semantic theory or framework of semantic theorizing. In other words, I shall begin with the difficult question of the empirical significance of semantic theorizing. In Sect. 2, I outline a relativist semantic theory, and in Sect. 3, I review four types of evidence that might be offered in favour of a relativistic framework. I show that the evidence is not conclusive because a sophisticated form of contextualism (or indexical relativism) can stand up to the evidence. However, the evidence can be taken to support the view that either relativism or the sophisticated form of contextualism is correct.     

得失程数的变化: 损失规避现象的新视点

损失规避是预期理论的核心部分之一, 指等量的损失和获得产生的心理效用并不相同, 前者大于后者。大量研究从生理、认知、情感等角度探讨损失规避的内在机制和规律, 以期认识、预测并控制损失规避导致的偏差。本研究假设损失规避与获得或损失的“程数”(route)有关, 以往研究发现了损失规避现象, 是由于其采用的“双程损失-单程获得”典型情境中, 损失程数多于获得程数。为检验该假设, 本研究设计了不同于传统范式的“获得和损失程数相等”的镜像情境、“单程损失－双程获得”及“三程获得”三种不同的得失情境。研究结果支持本假设: 当损失的程数等于或少于获得的程数时, 损失规避现象消失; 获得或损失的程数越多, 个体对其的心理感受强度趋于越高。建议未来研究进一步检验心理感受强度在程数和损失规避行为之间的中介作用。