Transverse diffusivity of cerebral parenchyma predicts visual tracking performance in relapsing–remitting multiple sclerosis

This study investigated the relation between cerebral damage related to multiple sclerosis (MS) and cognitive decline as determined by two classical mental tracking tests. Cerebral damage in 15 relapsing–remitting MS patients was measured by diffusion tensor imaging (DTI). Fractional anisotropy, longitudinal and transverse diffusivity were defined in the cerebral parenchyma. Cognitive performance of the MS patients was assessed with the oral response format of the Symbol Digit Modalities Test (SDMT) and the Paced Auditory Serial Addition Test (PASAT). A significant correlation was found between performance on the SDMT and the fractional anisotropy in the brain. This correlation was predominantly induced by transverse diffusivity. Transverse diffusivity refers to the diffusion across fibers rather than along the fibers and is believed to be a specific marker for axonal loss and demyelination associated with MS. No significant association between DTI-measures and PASAT performance was found and this negative finding was mainly attributed to psychometric qualities. These results indicate that diffusivity along the non-principal diffusion direction, a possible signature of MS-related white matter pathology, contributes to information processing speed as measured with the SDMT, a task that requires close visual tracking and a widely used clinical marker for cognitive decline in MS.     

Beyond quantity: Individual differences in working memory and the ordinal understanding of numerical symbols

In two different contexts, we examined the hypothesis that individual differences in working memory (WM) capacity are related to the tendency to infer complex, ordinal relationships between numerical symbols. In Experiment 1, we assessed whether this tendency arises in a learning context that involves mapping novel symbols to quantities by training adult participants to associate dot-quantities with novel symbols, the overall relative order of which had to be inferred. Performance was best for participants who were higher in WM capacity (HWMs). HWMs also learned ordinal information about the symbols that lower WM individuals (LWMs) did not. In Experiment 2, we examined whether WM relates to performance when participants are explicitly instructed to make numerical order judgments about highly enculturated numerical symbols by having participants indicate whether sets of three Arabic numerals were in increasing order. All participants responded faster when sequential sets (3-4-5) were in order than when they were not. However, only HWMs responded faster when non-sequential, patterned sets (1-3-5) were in order, suggesting they were accessing ordinal associations that LWMs were not. Taken together, these experiments indicate that WM capacity plays a key role in extending symbolic number representations beyond their quantity referents to include symbol-symbol ordinal associations, both in a learning context and in terms of explicitly accessing ordinal relationships in highly enculturated stimuli.     

The Never Land – loss of an idealized pre-birth place and the gain of a thinking mind

This paper describes the main themes in the psychotherapy of a severely epileptic girl, over a period of eleven years, aged 16 at the time of writing. For most of the therapy the girl lacked an ability to differentiate between herself and others, and therefore there was little development of rudimentary Oedipal conflicts. Her severe physical and mental impairments were inextricably linked to this fundamental problem in the process of separating: the physical problems compounding the emotional, and the emotional compounding the physical. Her mother's illnesses were significant factors. Throughout the girl's life she was subject to extreme medical interventions. The paper draws upon psychoanalytic models of mind and body integration, including notions of the 'biopsychosocial dysregulation' model of illness. The clinical material describes the girl's use of the dolls to populate a Peter Pan Never Land, with its many static perspectives, denying growth and the difference between the generations, although therein was the beginning of the use of symbolization. As the child's awareness of her physical impairments grew, so did her despair at her own and her mother's hopeless physical condition. However, she became more able to express her outrage, but with the life-saving awareness of a therapist who was not also ill. This led to the girl's increased ability to acknowledge differentiation between self and other, further painful awareness of her disabilities, losses and possible death, as well as those of her ill mother and, gradually, an ability to acknowledge the passing of time and an appreciation therein of a healthy separate thinking part of her that could use symbolization and allow for some separateness and some emotional growth.     

The interactive evolution of human communication systems

This paper compares two explanations of the process by which human communication systems evolve: iterated learning and social collaboration. It then reports an experiment testing the social collaboration account. Participants engaged in a graphical communication task either as a member of a community, where they interacted with seven different partners drawn from the same pool, or as a member of an isolated pair, where they interacted with the same partner across the same number of games. Participants' horizontal, pair-wise interactions led "bottom up" to the creation of an effective and efficient shared sign system in the community condition. Furthermore, the community-evolved sign systems were as effective and efficient as the local sign systems developed by isolated pairs. Finally, and as predicted by a social collaboration account, and not by an iterated learning account, interaction was critical to the creation of shared sign systems, with different isolated pairs establishing different local sign systems and different communities establishing different global sign systems.     

Being seaward-handed: a computational model of the acquisition of language-specific spatial references

Empirical findings of cross-linguistic studies reveal three different frames of spatial reference: intrinsic, relative, and absolute. Of special interest are relative and absolute systems because they have antagonistic logical implications concerning the dependence on standpoint and orientation of the speaker/hearer. On the background of these findings it becomes crucial to show how an agent can form such language-specific spatial representations. In this paper, the system Locator is introduced as a model of concept formation in the spatial domain. It is assumed that an agent creates necessary discriminative features in processes of self-organization and selection and cannot just discover or find them in its environment. A number of simulations show that agents successfully create concepts of either a relative system (German) or an absolute system (Marquesan), relying solely on multimodal input (visual and linguistic).

Using relations within conceptual systems to translate across conceptual systems

According to an "external grounding" theory of meaning, a concept's meaning depends on its connection to the external world. By a "conceptual web" account, a concept's meaning depends on its relations to other concepts within the same system. We explore one aspect of meaning, the identification of matching concepts across systems (e.g. people, theories, or cultures). We present a computational algorithm called ABSURDIST (Aligning Between Systems Using Relations Derived Inside Systems for Translation) that uses only within-system similarity relations to find between-system translations. While illustrating the sufficiency of a conceptual web account for translating between systems, simulations of ABSURDIST also indicate powerful synergistic interactions between intrinsic, within-system information and extrinsic information.     

有关具身认知的三种理论模型

具身认知强调了身体在认知中的关键作用,主张身体的构造和状态、身体的物理属性及其大脑与身体的特殊感觉—运动通道对认知的形成产生了根本影响。具身认知的相关理论虽然直接或者间接承认身体对心智的塑造关系,但是存在一些观点的不一致,导致具身认知理论难以统一到相同的框架上来,具身认知大致可以归结为三种模型:概念隐喻理论,知觉符号理论和感知运动模拟隐喻理论。     

Re-framing the characteristics of concepts and their relation to learning and cognition in artificial agents

In this work, the problems of knowledge acquisition and information processing are explored in relation to the definitions of concepts and conceptual processing, and their implications for artificial agents.The discussion focuses on views of cognition as a dynamic property in which the world is actively represented in grounded mental states which only have meaning in the action context. Reasoning is understood as an emerging property consequence of actions-environment couplings achieved through experience, and concepts as situated and dynamic phenomena enabling behaviours.Re-framing the characteristics of concepts is considered crucial to overcoming settled beliefs and reinterpreting new understandings in artificial systems.The first part presents a review of concepts from cognitive sciences. Support is found for views on grounded and embodied cognition, describing concepts as dynamic, flexible, context-dependent, and distributedly coded.That is argued to contrast with many technical implementations assuming concepts as categories, whilst explains limitations when grounding amodal symbols, or in unifying learning, perception and reasoning.The characteristics of concepts are linked to methods of active inference, self-organization, and deep learning to address challenges posed and to reinterpret emerging techniques.In a second part, an architecture based on deep generative models is presented to illustrate arguments elaborated. It is evaluated in a navigation task, showing that sufficient representations are created regarding situated behaviours with no semantics imposed on data. Moreover, adequate behaviours are achieved through a dynamic integration of perception and action in a single representational domain and process.     

Rapid learning of syllable classes from a perceptually continuous speech stream

To learn a language, speakers must learn its words and rules from fluent speech; in particular, they must learn dependencies among linguistic classes. We show that when familiarized with a short artificial, subliminally bracketed stream, participants can learn relations about the structure of its words, which specify the classes of syllables occurring in first and last word positions. By studying the effect of familiarization length, we compared the general predictions of associative theories of learning and those of models postulating separate mechanisms for quickly extracting the word structure and for tracking the syllable distribution in the stream. As predicted by the dual-mechanism model, the preference for structurally correct items was negatively correlated with the familiarization length. This result is difficult to explain by purely associative schemes; an extensive set of neural network simulations confirmed this difficulty. Still, we show that powerful statistical computations operating on the stream are available to our participants, as they are sensitive to co-occurrence statistics among non-adjacent syllables. We suggest that different learning mechanisms analyze speech on-line: A rapid mechanism extracting structural information about the stream, and a slower mechanism detecting statistical regularities among the items occurring in it.     

And the dish ran away with the spoon: a hodgepodge of reflections,as rigorous as they are rambling,on the true subject

In this article, the topic of ‘the true subject’ is explored in terms of a dialectical mode thinking which is in keeping with Jung's great insight concerning psychology's lack of an Archimedean vantage‐point distinct from its topics and subject matters. Evocative and expository, the emphasis is upon the performative poetics of such thinking within the sphere of our soul‐making. The interpretative mode of practice presented in the article is richly illustrated with examples from Biblical texts, literary images, and proverbial sayings, as well as from the sur‐real of nursery rhyme and the genre of the murder mystery. Essential insights of Jung's concerning the infinite and the finite as dimensions of self are revisited in terms of that contemporary trend of Jungian thought known as psychology as the discipline of interiority.