前临床期痴呆的认知特征：当前研究进展和未来研究展望

在这篇文章中, 我将讨论从正常老化到痴呆, 这一通常被称为痴呆前临床阶段的认知功能的转变。研究表明, 阿尔茨海默症和血管性痴呆病人在临床确诊之前的几年中, 会出现明显的认知损伤。早期最突出的损伤存在于情节记忆、加工速度以及执行功能。这些功能性损伤与神经生物学研究证实的边缘系统和新皮层区存在多重损伤是相一致的。虽然早在临床诊段之前, 病人组和控制组的平均成绩存在巨大差异, 但同时这两组测试成绩的分布在很大程度上是重叠的。寻求降低这种重叠度的方法是未来研究的一个重要任务。这有可能通过将认知的和其他指标(如基于脑的、基因的、临床的、社会的)相结合构建预测模型来实现。此外, 在未来研究中以下三方面也是急需考虑问题: (a) 找出在 前临床期间认知功能急速下降的时间点: (b) 评估从前临床到临床诊断变化速率中存在的个体差异; (c) 确定特定因素与随后发生的痴呆之间的关联强度是如何随时间向临床确诊推进而逐渐变化的。     

Risky behavior in young adult pedestrians: Personality determinants,correlates with risk perception,and gender differences

Based on the risk homeostasis theory, the aim of this study was to assess acceptable risk, measured by personality factors, and risk perception, measured by physiological arousal, as predictors of risky behavior in young adult pedestrians, as well as to assess for gender differences. Eighty-two young adults, aged 18–30, completed self-report measures about risky pedestrian behaviors and these personality traits: impulsiveness, conscientiousness and openness to experience. Sixty-four of these participants then took part in an experimental task designed to assess their perception of the level of risk in situations involving different interactions between cars and pedestrians. Risk perception was assessed by these physiological responses: heart rate, skin conductance level, and skin conductance response. Results showed that risky behavior had significant correlations with impulsiveness, conscientiousness, and skin conductance level. Gender differences also emerged in risky behavior, impulsiveness, conscientiousness, and skin conductance level. Finally, a structural equation model showed that impulsiveness, conscientiousness and the difference in skin conductance level between risky and neutral situations predicted risky pedestrian behaviors, and explained 23.6% of the its variance, after controlling the effect of gender. Implications for evaluation, prevention, and intervention for risky pedestrian behaviors are discussed.     

Driving construals: Personal Construct Theory in a reckless driving context

With research revealing low road safety campaign efficacy and links between reckless driving behaviors and crash frequency, further investigation into the foundations and composition of driver education and training is required. Through two studies, the current research aimed to develop a measure that utilized the principles of Kelly’s (1955) Personal Construct Theory to (a) elicit constructs, or construals, specific to selected elements of reckless driving behaviors, (b) pilot a method in which the elicited constructs could be measured by asking participants to choose those they deemed most important, (c) group participants based on their constructs, and (d) assess between-group differences in self-reported reckless driving behavior. Results suggest that drivers can be categorized based on the constructs they use, and that rates of self-reported past engagement in reckless driving behavior, and willingness to do so in the future, vary systematically between these construal-based driver categories. Continuing research is required to develop and test applications of these findings.     

Disaster risk reduction: Psychological perspectives on preparedness

Facilitating people's ability to anticipate, prepare for and recover from disaster is an important component of the UNISDR strategy for disaster risk reduction. Following a discussion of the functional characteristics of preparedness, this paper first discusses how hazard characteristics and psychological constructs influence people's ability to anticipate uncertain future events. It then reviews how psychological theories (Health Belief Model, Protection Motivation Theory, PrE Theory, Theory of Planned Behaviour, Critical Awareness Theory, Social Marketing, Protective Action Decision Model, Social Capital, Community Engagement Theory and Social Identity Theory) can inform understanding of preparedness for likely and current hazard events. Discussion then then turns to applying concepts and theories to understanding preparedness for current disasters. The all-hazards and cross-cultural applicability of preparedness theory is discussed, as are a need for a critical appraisal of preparedness, its predictors, and the nature and development of the preparedness process and its application in facilitating effective intervention strategies.     

The development of violence from age 8 to 61

The main aim of this study is to investigate the development of violence from childhood to adulthood. In the Cambridge Study in Delinquent Development (CSDD), 411 London males have been followed up from age 8 to 48 in interviews, and from age 10 to 61 in criminal records; 19% were convicted for violence. There was a surprising amount of violence committed at older ages (40–61). The number of violence convictions was similar at ages 10–20, 21–39, and 40–61. There was considerable continuity in violent offending from ages 10–20 to 40–61. There was also continuity in self-reported violence from ages 15–18 to 43–48, and violence convictions were related to self-reported violence at all ages. The most important childhood risk factors for violence convictions were high daring or risk-taking, low verbal intelligence, a disrupted family, harsh parental discipline, high hyperactivity, and large family size. The extent to which these risk factors predicted violence at ages 40–61 was noteworthy. The “integrated cognitive antisocial potential (ICAP)” theory was proposed to explain the development of violence, and methods of preventing violence, targeting childhood risk factors, were reviewed.     

Violence Exposure and Sexual Risk Behaviors for African American Adolescent Girls: The Protective Role of Natural Mentorship and Organizational Religious Involvement

African American adolescent girls are at increased risk of being exposed to community violence and being diagnosed with a sexually transmitted infection. Fewer studies, however, have examined the protective roles of natural mentorship and organizational religious involvement as potential moderators that could lessen the effects of violence exposure on health risk behavior. Data from 273 African American ninth grade girls were used to test hypothesized independent and moderated‐moderation models. Results suggest that natural mentorship and religious involvement were protective for girls who reported at least one mentor and moderate to high levels of religious involvement. Our findings may be relevant for community stakeholders and organizations that directly interact with religious institutions and community programs that focus on outreach to African American adolescent girls.     

Too good to be true? Psychological responses to uncommon options in risk–reward environments

Risks and rewards, or payoffs and probabilities, are inversely related in many choice environments. We investigated people's psychological responses to uncommon combinations of risk and reward that deviate from learned regularities (e.g., options that offer a high payoff with an unusually high probability) as they evaluated risky options. In two experiments (N = 183), participants first priced monetary gambles drawn from environments in which risks and rewards were negatively correlated, positively correlated, or uncorrelated. In later trials, they evaluated gambles with uncommon combinations of risk and reward—that is, options that deviated from the respective environment's risk–reward structure. Pricing, response times, and (in Experiment 2) pupil dilation were recorded. In both experiments, participants took more time when responding to uncommon compared to foreseeable options or when the same options were presented in an uncorrelated risk–reward environment. This result was most pronounced when the uncommon gambles offered higher expected values compared to the other gambles in the set. Moreover, these uncommon, high‐value options were associated with an increase in pupil size. These results suggest that people's evaluations of risky options are based not only on the options' payoffs and probabilities but also on the extent to which they fit the risk–reward structure of the environment.     

Efficacy of a Brief,School‐Based Bystander Bullying Intervention on High School Students' Alcohol Use

The authors examined the efficacy of a brief bystander bullying intervention on reducing alcohol use among high school students (N = 61). As hypothesized, high‐risk drinkers in the intervention group reported reduced drinking compared with control students at a 30‐day follow‐up.     

Impact of maternal adverse childhood experiences on child socioemotional function in rural Kenya: Mediating role of maternal mental health

Mothers in low‐ and middle‐income countries (LMIC) suffer heightened vulnerability for adverse childhood experiences (ACEs), which is exacerbated by the multitude of risk factors associated with poverty and may lead to increased risk of psychiatric disorder. The constellation of complex, co‐occurring biological, environmental, social, economic and psychological risk factors are in turn transmitted to her child, conferring vulnerability for adverse development. This study examines the association between maternal intra‐ and extra‐familial ACEs, maternal education and the mental health of her child, mediated by maternal mental health. Mother‐child dyads (n = 121) in Machakos, Kenya were examined cross‐sectionally using self‐report measures of ACEs, maternal mental health and child internalizing and externalizing mental health problems. The four models proposed to examine the relationship between intra‐ and extra‐familial maternal ACEs and child internalizing and externalizing problems demonstrated indirect pathways through maternal mental health. These effects were found to be conditional on levels of maternal education, which served as a protective factor at lower levels of maternal ACEs. These models demonstrate how the impact of ACEs persists across the lifespan resulting in a negative impact on maternal mental health and conferring further risk to subsequent generations. Elucidating the association between ACEs and subsequent intergenerational sequelae, especially in LMIC where risk is heightened, may improve targeted caregiver mental health programs for prevention and intervention.