Mapping people's positions regarding the acceptability of somatic gene therapy

IntroductionAs gene therapy entails potential drawbacks, studies are needed in order to know people's opinions regarding its use.ObjectivesThe present study examined French people's positions regarding somatic gene therapy.MethodA sample of 224 adults living in various areas in France was presented with 32 realistic scenarios that were created by orthogonally combining the levels of four factors: the type of illness (e.g., hemophilia), the probability of transmission of the pathogenic gene, the technique used (e.g., transfer of a functional gene just after birth), and le probability of success of the therapy.ResultsThrough cluster analysis, six qualitatively different positions were found: Never very acceptable (8% of the sample, mostly males and more educated people), Legalist (17%, mostly people who have been informed of the legal and technical aspects of the therapy), Depends on the chances of success (18%), Fully acceptable after birth (5%), Fully acceptable before birth (8%), and Quite always acceptable (33%, mostly older people with children).ConclusionAlthough it has some few detractors, the recourse to gene therapy seems to be well accepted by a majority of the participants, and this high level of acceptation hold whether the pathology considered is hemophilia, immunodeficiency, propensity to develop cancer, or cardiovascular pathology.     

Factorial validation and measurement invariance of the French version of the multidimensional competitive orientation inventory (FVMCOI) in the sport field

IntroductionLittle is known about the importance of the adaptive, maladaptive and neutral facets of competitive orientations among French athletes.ObjectiveThe aim of this study is to test the factorial validation and measurement invariance of the French version of the multidimensional competitive orientation inventory (FVMCOI) from the original version (MCOI, Orosz et al., 2018), which included 12 items and four factors (i.e., hypercompetitive orientation, self-developmental competitive orientation, anxiety-driven competition avoidance, and lack of interest toward competition).MethodA series of three complementary studies was carried out with a total sample of 891 competitors.ResultsFollowing cross-cultural validation methods a preliminary version of the FVMCOI was constructed and the clarity of its items was established (study 1). Then, exploratory structural equation modeling (ESEM) confirmed that the four-factor model for the FVMCOI was factorially valid, and consistent with the model of the original version. As such, the multiple-group invariance tests showed that the FVMCOI was partially invariant across both age and gender and fully invariant across type of sport, level of competition and over time (study 2). Finally, the concurrent validity of the FVMCOI was demonstrated through its expected relationships with achievement goals, competitive aggressiveness and anger in sport (study 3).ConclusionThe establishment of the FVMCOI extends the research in sport psychology by allowing an extensive psychometric study of the MCOI in the sport domain and providing deeper insights into the healthy, unhealthy, and neutral nature of competitive orientation in this context. The FVMCOI's potential practical applications in sport context, with some limitations and perspectives of this study, are also discussed.     

Safety of micro-mobility: Riders’ psychological factors and risky behaviors of cargo TTWs in China

Cargo two- or three-wheeled vehicles (TTWs), as a new form of micro-mobility, have become a popular mode of urban cargo transportation in China. Cargo TTW riders’ psychological factors and risky behaviors lead to a number of accidents. A questionnaire is designed by comprehensively considering these factors and behaviors of cargo TTW riders that includes eleven risk factors to quantitatively analyze the risky behaviors based on structural equation modeling (SEM). One thousand three hundred nineteen participants reported using cargo TTWs on a questionnaire distributed across the country. The characteristics of riding behavior data are analyzed to verify the three-layer risk theoretical framework of “Psychological factors (Personality traits/specific factors) - Psychological acceptability of risks (confidence/perception/attitude) - Risky behaviors”. The results show that anger has a strong direct effect on riding violations, while normlessness and altruism have a direct effect on riding errors. Workload has a weak but direct effect on risky behaviors, and riding feedback has a weak and mixed effect. In addition, high-risk groups are identified by analysis of variance (ANOVA) with rider population attributes. These quantitative analyses can help guide safety countermeasures to mitigate accidents involving cargo TTWs.     

A person-centred approach to understanding dark-side antecedents and students’ outcomes associated with physical education teachers’ motivation

The present study firstly establishes physical education (PE) teachers’ motivational profiles based on their autonomous motivation, controlled motivation and amotivation and, secondly, investigates how different PE teachers’ motivational profiles differ in terms of certain maladaptive antecedents (i.e. psychological need frustration, pressures perceived at work and burnout). It also addresses the differences in their students’ perception of autonomy support, psychological need satisfaction and autonomous motivation. A total of 105 PE teachers and their 2164 students completed validated questionnaires. Four profiles were retained in the cluster analysis. Results showed that teachers who were high on autonomous motivation displayed the most optimal pattern of outcomes, whereas teachers who were high on amotivation showed the opposite pattern. Analysis of the established profiles suggested that the experience of controlled motivation was linked with maladaptive outcomes among both teachers and students. Implications for educational policy and practice are discussed.     

The silent music sheet,the replica tin and the unsewn button: Materialising nostalgia in the Marks and Spencer's archive

This paper explores how nostalgia and collective memory are materialised, imagined, curated and orchestrated through the archive. Drawing upon the example of the Marks and Spencer's (M&S) archive, we argue that archives, particularly those containing objects, command nostalgia. They re-appropriate objects, memories and their histories into contemporary narratives. This paper adds to a body of work within and beyond geography and sociology exploring the potency and creativity of everyday materials and their ability to produce, imagine and memorialise affinities between people, places and past times. This raises questions about the politics of memory, the authenticity of objects and the nostalgic imaginaries they enliven, what we discuss as ‘faux nostalgia’. We illustrate how M&S is part of collective British memory, promoting middle-class ideals of British family life. The archive and objects on display materialise such imaginaries, creating a yearning for the spirit, values and opportunities of times gone by; interweaving them into contemporary narratives of family life to create unattainable ideals. We reflect upon the biographies of three objects from the archive: a music sheet, an unsewn button and a replica tin. By making these objects central to our account, we illustrate how they materialise and recollect nostalgia through the archive.     

Understanding the role of configural processing in face emotion recognition in Parkinson’s disease

This investigation examined whether impairment in configural processing could explain deficits in face emotion recognition in people with Parkinson’s disease (PD). Stimuli from the Radboud Faces Database were used to compare recognition of four negative emotion expressions by older adults with PD (n = 16) and matched controls (n = 17). Participants were tasked with categorizing emotional expressions from upright and inverted whole faces and facial composites; it is difficult to derive configural information from these two types of stimuli so featural processing should play a larger than usual role in accurate recognition of emotional expressions. We found that the PD group were impaired relative to controls in recognizing anger, disgust and fearful expressions in upright faces. Then, consistent with a configural processing deficit, participants with PD showed no composite effect when attempting to identify facial expressions of anger, disgust and fear. A face inversion effect, however, was observed in the performance of all participants in both the whole faces and facial composites tasks. These findings can be explained in terms of a configural processing deficit if it is assumed that the disruption caused by facial composites was specific to configural processing, whereas inversion reduced performance by making it difficult to derive both featural and configural information from faces.     

Exploring the complex emotional relationships that influence children's participation rights in early childhood education settings

Early childhood educators engage in complex and emotional work in their professional role educating and caring for children aged from birth to five years. The aim of this paper is to promote autoethnography as a most suitable method of understanding the role emotions play in the actualisation of young children's participation rights in early childhood education services. The author is a practising educator and draws upon a specific auto-ethnographic account of practice, the story of Sarah, as the focus of this paper to explore the emotional intensity of relationships in early childhood education. Autoethnography is discussed as a method to sit alongside ‘traditional’ ethnographic research to provide a deep understanding of the role of the educator embracing and enacting a rights approach in their work and what influences their decision making. In conclusion the author suggests autoethnography is a useful reflexive tool for educators to consider the role of emotions as a catalyst for change to ensure the actualisation of children's participation rights in daily practice in early childhood education.     

父亲抑郁对幼儿问题行为的影响:教养效能感和教养方式的中介作用

以310名幼儿父亲为研究对象,采用流行病调查中心抑郁量表、父母教养能力感量表的教养效能感分问卷、父母教养方式评价量表和Conners儿童行为问卷,考察父亲教养效能感和教养方式在父亲抑郁与幼儿问题行为间的中介作用。结果显示:(1)父亲抑郁、专制粗暴、情感联系和幼儿问题行为两两之间均显著正相关,父亲教养效能感、民主关怀、宽容理解两两之间均显著正相关,父亲教养效能感、民主关怀、宽容理解分别与父亲抑郁、专制粗暴、情感联系和幼儿问题行为两两之间显著负相关;(2)父亲抑郁对幼儿问题行为具有显著的正向预测作用;(3)父亲教养效能感和自身的民主关怀、专制粗暴、情感联系不仅分别在父亲抑郁与幼儿问题行为之间起部分中介作用,而且在父亲抑郁与幼儿问题行为之间起链式中介作用。     

这不是我想象中的工作！不合规任务对新员工工作投入的影响

本研究基于情绪的认知评价理论,探讨了不合规任务对新员工工作投入的动态影响机制。通过收集分析71名新员工连续5个工作日的追踪数据发现,不合规任务会诱发新员工的不愉快情绪,进而影响其工作投入,工作成长观能够有效缓冲这一负面影响。以上结论拓宽了不合规任务的影响后果,并为如何干预不合规任务给新员工带来的消极影响提供了启示。     

Disrupted memory inhibition in dementia of Alzheimer’s type

Cognitive inhibition has been suggested to deteriorate in Alzheimer’s disease. While numerous studies with different experimental paradigms found evidence on impaired inhibition in attention and memory, evidence in favour of intact memory inhibition has been reported with regard to the phenomenon of retrieval-induced forgetting (Moulin et al., 2002). Here, we adapted the previously used paradigm in order to reduce the contribution of non-inhibitory processes and examined whether retrieval-induced forgetting could still be observed in a sample of participants with diagnosed Alzheimer’s disease. In contrast to the previous finding, we found that retrieval-induced forgetting only occurred in an age-matched control group. These results suggest that inhibitory deficits in Alzheimer’s disease also generalize to memory inhibition that resolves interference occurring during retrieval, whereas effects of retrieval-induced forgetting may still occur when non-inhibitory causes, such as, blocking by previously retrieved content, are not precluded.