神经管缺陷的病因、预防与产前控制

根据《中国人群死亡及其危险因素流行水平、趋势和发布》的报告和相关研究表明,全世界约有1亿人患有抑郁症,且数量有增无减,抑郁症将成为本世纪一种相当流行的病症。由于抑郁症是一种患病率高,严重危害人类身心健康,具有高自杀风险的精神疾病,更需要我们采取措施积极预防。目前采用的主要预防方法有:积极的心理健康教育、处理好家庭与社会的关系、社会支持、心理调适和体育锻炼等。     

A Cognitive Psychophysiological Model to Predict Functional Decline in Chronically Stressed Older Adults

The current study evaluated whether psychological distress (composite of depression, anxiety, vital exhaustion), inflammation (C-reactive protein, CRP) and cognitive function (Digit Symbol Test, DST) and their changes mediated the relationship between caregiver status and functional decline. Caregivers for spouses with Alzheimer’s disease were compared to demographically-similar non-caregiver spouses at study entry (T1), T2 (1 year later), and T3 (2 years after T1). Caregivers had greater functional impairment, higher distress scores, and poorer DST scores at all points of measurement and also showed functional decline. Non-caregivers did not demonstrate functional decline. Caregivers declined 85% faster than did non-caregivers. Regressions showed that after controlling for functional impairment at T1, illness, medication, and health behavior covariates, psychological distress at T1 and increases in CRP from T1 to T3 mediated the difference in functional decline. Moreover, after DST decline from T1 to T2 was entered in the model, caregiver status, psychological distress and increases in inflammation all showed reductions in their predictive importance. These findings suggest psychological distress and increases in inflammation may help explain why caregivers show greater functional decline than non-caregivers. However, the influences of these psychophysiological variables may be driven in part by cognitive decline prior to functional decline. This article is based upon an invited address, “Potential Hazards of Caring for a Loved One with Alzheimer’s Disease” given by the first author in recognition of the author’s receipt of the Association of Psychologists in Academic Health Centers 2005 Award for Distinguished Achievement in Research. The address was presented at the Annual meeting of the American Psychological Association, New Orleans, LA., August, 2006.     

Buddhist and Western perspectives on suffering,stress, and coping

The distinct definition of stress postulated by Buddhist and Western cultures is the foundation for their different coping styles, traditions, and practices. Dukkha, derived from Buddha’s Four Noble Truths, appears on the surface similar to psychological stress. Further examination of the Eastern cosmology yields a fundamental disagreement between Western psychological theory and Buddhists’ conception of suffering and stress related to incorporating reality into the formulation. Cross-cultural research on traditional approaches to coping with occupational stress found that problem solving was the most effective strategy, however in Thailand meditation helped nurses cope with a variety of stressors such as dealing with death and dying. Paul Tyson Ph.D is a professor of psychology and teaches perception, Western and Eastern consciousness at Brock University, St. Catharines, Ontario, Canada L2S 3A1. His research publications have ranged from lucid dreams to memory enhancement after drinking alcohol, but his primary focus has been on EEG biofeedback, stress management, and current cross-cultural publications are on how Buddhists cope with stress. Correspond with Paul Tyson via e-mail at tyson@brocku.ca Rana Pongruengphant R.N., Ph.D. is an associate professor in the Faculty of Nursing and Vice-President for Academic Affairs at Burapha University, Bangsaen, Chonburi, Thailand 20131. She teaches nursing administration, nursing research and computers for research. Her publications ranged from nursing administration, nursing practice, nursing education, and cross-cultural studies of coping with occupational stress.Correspond with Rana Pongruengphant via e-mail at rena@bucc.ac.th     

Price as a quality or sacrifice cue: Role of goal orientation

Prior research seems to have neglected the factors that influence consumers to use price information as an indicator of quality or sacrifice. Based on the concept of 'goal looms larger', Study 1 in the present research demonstrated that the extent to which consumers use price information as an indicator of quality or sacrifice is a function of consumer goal (promotion focus vs prevention focus). Study 2 demonstrated that extremeness aversion is a function of consumer goal. The extent of extremeness aversion is significantly greater for prevention-focused consumers than for promotion-focused consumers.     

Coping with challenge and hindrance stressors in teams: Behavioral,cognitive, and affective outcomes

The purpose of this study was to utilize the challenge–hindrance framework to examine the discrete and combined effects of different environmental stressors on behavioral, cognitive, and affective outcomes at the team level. Results from 83 teams working on a command and control simulation indicated that the introduction of a challenge stressor positively affected team performance and transactive memory. The introduction of a hindrance stressor negatively affected team performance and transactive memory and positively affected psychological withdrawal. When the hindrance stressor was combined with the challenge stressor, teams exhibited the lowest levels of performance and transactive memory, and the highest levels of psychological withdrawal. These effects were due to the adoption of specific coping strategies by team members. Implications are discussed, as well as limitations and directions for future research.     

The Role of Perceived Social Support and Stress in the Type A Cognition-Symptom Relationship

The two main objectives of this research were to determine whether Type A cognitions are related to a broader range of symptoms than has traditionally been studied and to determine possible mediating variables. Past research and theory suggest that Type A individuals not only experience but also generate stress and interpersonal conflict (i.e., in keeping with a psychosocial vulnerability model). This psychosocial vulnerability may put Type A individuals at greater risk of experiencing a wide array of physical and psychological symptoms well beyond coronary heart disease (CHD), the health outcome typically investigated. Stress, interpersonal and non-interpersonal in nature, and perceived social support, were explored as possible mediators in the Type A cognition-symptoms relationship using structural equation modelling (SEM) in a university sample. Non-interpersonal stress and interpersonal stress mediated both the Type A cognition-psychological symptoms relationship and the Type A cognition-physical symptoms relationship. However, perceived social support only mediated the Type A cognition-psychological symptoms relationship. Results indicate that Type A individuals may experience psychosocial vulnerability, particularly reporting stress, which may put them at risk for the experience of negative health outcomes. Implications for cognitive therapy are discussed.

初探健康管理与我国糖尿病的预防与控制

近年来,我国糖尿病发展的势头迅速,成为糖尿病患病率增长最快的国家之一,给社会和经济带来了巨大的负担。文章针对我国的糖尿病的流行现状及其带来的经济负担,分析了实施糖尿病健康管理的现实意义,并借鉴美国健康管理的经验,构思了我国社区的促进糖尿病防制的健康管理模式。     

浅谈心血管疾病预防的重要性和可操作性

心血管疾病是人类死亡的主要病因,其危险因素包括吸烟、血脂异常、糖尿病、高血压、肥胖等。目前我国医务工作者限于治疗疾病,忽视疾病预防,这种模式过于被动,需要高昂的医疗支出。如果不做好心血管疾病的预防工作,将会极大影响国民经济增长。因此改善生活方式、预防心血管疾病发生,形成疾病预防模式就显得尤为重要,并具有可操作性。     

雷公藤多苷对肝脏的双重作用及其思考

文献研究表明,雷公藤多苷既可治疗肝脏疾病,又能引起肝脏毒性。本文对其双重作用从不同角度进行了分析,认为药物均存在治疗作用和毒副作用的双重效应,且与用药剂量、时间密切相关,并从严控剂量时间、加强监测、重视“治未病”、改进剂型等方面提出了应对措施。     

某院医务人员职业暴露的现状调查

职业暴露是医务人员最常见的职业伤害,为探求有效的防护方法,对我院2005年至2008年报告的职业暴露进行了分析,结果发现医务人员职业暴露漏报严重,护士发生职业暴露最多（占57．4％）,主要为针刺伤（占85．2％）,暴露源以乙型肝炎为主（占53．2％）。应加强医务人员标准预防和职业安全知识的教育与培训,建立和健全职业暴露的监测体系。