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951.
A land use many‐objective optimization problem for a 1500‐ha farm with 315 paddocks was formulated with 14 objectives (maximizing sawlog production, pulpwood production, milksolids, beef, sheep meat, wool, carbon sequestration, water production, income and Earnings Before Interest and Tax; and minimizing costs, nitrate leaching, phosphorus loss and sedimentation). This was solved using a modified Reference‐point‐based Non‐dominated Sorting Genetic Algorithm II augmented by simulated epigenetic operations. The search space had complex variable interactions and was based on economic data and several interoperating simulation models. The solution was an approximation of a Hyperspace Pareto Frontier (HPF), where each non‐dominated trade‐off point represented a set of land‐use management actions taken within a 10‐year period and their related management options, spanning a planning period of 50 years. A trade‐off analysis was achieved using Hyper‐Radial Visualization (HRV) by collapsing the HPF into a 2‐D visualization capability through an interactive virtual reality (VR)‐based method, thereby facilitating intuitive selection of a sound compromise solution dictated by the decision makers' preferences under uncertainty conditions. Four scenarios of the HRV were considered emphasizing economic, sedimentation and nitrate leaching aspects—giving rise to a triple bottomline (i.e. the economic, environmental and social complex, where the social aspect is represented by the preferences of the various stakeholders). Highlights of the proposed approach are the development of an innovative epigenetics‐based multi‐objective optimizer, uncertainty incorporation in the search space data and decision making on a multi‐dimensional space through a VR‐simulation‐based visual steering process controlled at its core by a multi‐criterion decision making‐based process. This approach has widespread applicability to many other ‘wicked’ societal problem‐solving tasks. Copyright © 2014 John Wiley & Sons, Ltd.  相似文献   
952.
Adjustment disorders (AjD) are among the most frequent mental disorders yet often remain untreated. The high prevalence, comparatively mild symptom impairment, and transient nature make AjD a promising target for low-threshold self-help interventions. Bibliotherapy represents a potential treatment for AjD problems. This study investigates the effectiveness of a cognitive behavioral self-help manual specifically directed at alleviating AjD symptoms in a homogenous sample of burglary victims. Participants with clinical or subclinical AjD symptoms following experience of burglary were randomized to an intervention group (n = 30) or waiting-list control group (n = 24). The new explicit stress response syndrome model for diagnosing AjD was applied. Participants received no therapist support and assessments took place at baseline, after the one-month intervention, and at three-month follow-up. Based on completer analyses, group by time interactions indicated that the intervention group showed more improvement in AjD symptoms of preoccupation and in post-traumatic stress symptoms. Post-intervention between-group effect sizes ranged from Cohen’s d = .17 to .67 and the proportion of participants showing reliable change was consistently higher in the intervention group than in the control group. Engagement with the self-help manual was high: 87% of participants had worked through at least half the manual. This is the first published RCT of a bibliotherapeutic self-help intervention for AjD problems. The findings provide evidence that a low-threshold self-help intervention without therapist contact is a feasible and effective treatment for symptoms of AjD.  相似文献   
953.
954.
The current experiment examined the factors that determine acquisition for elements of highly structured serial patterns. Three groups of rats were trained on three patterns with parallel rule‐based hierarchical structure, but with 3‐, 4‐, or 5‐element chunks, each with a final violation element. Once rats mastered their patterns, probe patterns were introduced to answer several questions. To assess the extent to which the learned response pattern depended on intrachamber location cues for anticipating different element types, Spatial Shift Probes shifted the starting lever of patterns to locations that positioned chunk boundaries where they had never been experienced during training. To assess the extent to which a phrasing cue is necessary for rats to perform a chunk‐boundary response, a Cue Removal Probe tested whether rats would produce a chunk‐boundary response in the correct serial position if the phrasing cue was omitted. To assess the extent to which cues from multiple trials leading up to the violation element are required to anticipate the violation element, Multiple‐Item Memory Probes required rats to make an unexpected response on one of the elements in the last two chunks of the pattern prior to the violation element. The results indicated that rats used multiple concurrent learning and memory processes to master serial patterns, including discrimination learning, rule learning, encoding of chunk length, and multiple‐item memories.  相似文献   
955.
《Médecine & Droit》2016,2016(137):37-47
Generate a human organ in an animal in order to elaborate a stock of available organs for transplantation… This is not the scenario of a science fiction movie but the result of the hard work of some researchers convinced of the feasibility of this major innovation. If the interest of this discovery is undeniable, it generates also many ethical and legal questions.  相似文献   
956.
《Médecine & Droit》2016,2016(141):147-153
The right to health protection is recognized as a constitutional objective. This includes guaranteeing an equal access to health care without any discrimination. The implementation of this right is a difficult task due to geographical and socioeconomic inequalities. In many situations, the public health sector is experiencing financial crises. The problems concerning health access seem to be mounting and could jeopardise the principle of solidarity which is the foundation of the health system.  相似文献   
957.
《Médecine & Droit》2014,2014(128):120-123
Setting a total length for time off work is a forensic act that all physicians must be able to perform. Given the importance of the legal consequences of this evaluation, it seems desirable that this practice is mastered by all practitioners. However, in practice there is often a disparity between forensic assessments and evaluations provided by other practitioners. To assess this difference in evaluation, we conducted a retrospective study, looking at 4 years of archives, of victims of Marseille's forensic service (CHU Timone), and highlighted a disparity between medical examiners, GPs and emergency physician's assessments. In both comparisons between medical examiners versus GPs (n = 367) or medical examiners versus emergency physicians (n = 511), were found in one third of cases of forensic requalification. The majority of checks on where GP's (80%) determined on over 8 days leave were reassessed under this limit by a medical examiner. This trend is reversed for the majority of (61%) requalification cases of emergency assessments (assessment over eight days by medical examiners. This study, proving a fact long suspected, raises many questions about these disparities evaluation we have discussed.  相似文献   
958.
《Médecine & Droit》2014,2014(124):23-25
The publication in the Official Journal of Law No. 2013-715 of August 6th 2013 which authorizes under conditions embryos and embryonic stem cells research is a milestone in the legal and ethical field in France. Indeed, the new Article L. 2151-5 of the Public Health Code replaces the prohibition regime of embryos and embryonic stem cells research by an authorization regime, which raises the question of the value and the protection of embryonic life in French law.  相似文献   
959.
In secularising Germany the aim of religious education (RE) is under discussion. The churches opt for denominational education familiarising the students with their own religious tradition. Humanists claim an ethical education, giving students objective information about different religions. Which perspective do students who will become RE teachers take in this discussion? Does their religiosity affect this perspective? All over Germany 1828 first-year students (with an average age of 21; 81% females; 72% Catholic and 28% Protestant) completed a relevant questionnaire. The respondents favour a RE which offers objective information. Most of them are pluralist thinkers in religious terms and show a moderate religious practice. The more relativist the students are thinking in religious terms, the more they tend to favour objective information. These findings challenge the churches’ perspective on RE, because even future RE teachers do not agree with the churches’ ideal on RE. A reformulation of this approach on cognitive level will be discussed.  相似文献   
960.
Blind people’s inferences about how other people see provide a window into fundamental questions about the human capacity to think about one another’s thoughts. By working with blind individuals, we can ask both what kinds of representations people form about others’ minds, and how much these representations depend on the observer having had similar mental states themselves. Thinking about others’ mental states depends on a specific group of brain regions, including the right temporo-parietal junction (RTPJ). We investigated the representations of others’ mental states in these brain regions, using multivoxel pattern analyses (MVPA). We found that, first, in the RTPJ of sighted adults, the pattern of neural response distinguished the source of the mental state (did the protagonist see or hear something?) but not the valence (did the protagonist feel good or bad?). Second, these neural representations were preserved in congenitally blind adults. These results suggest that the temporo-parietal junction contains explicit, abstract representations of features of others’ mental states, including the perceptual source. The persistence of these representations in congenitally blind adults, who have no first-person experience with sight, provides evidence that these representations emerge even in the absence of relevant first-person perceptual experiences.  相似文献   
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