Ethics and patentability in biotechnology

The systems of patent rights in force in Europe today, both at the level of national law and on the regional level, contain general clauses prohibiting the patenting of inventions whose publication and exploitation would be contrary to “ordre public” or morality. Recent years have brought frequent discussion about limiting the possibility of patent protection for biotechnological inventions for ethical reasons. This is undoubtedly a result of the dynamic development in this field in the last several years. Human genome sequencing, the first successful cloning of mammals, and the progress in human stem cell research present humanity with many new questions of an ethical nature. Directive 98/44 of the European Parliament and of the Council of July 6, 1998, on the Legal Protection of Biotechnological Inventions created a new basis for patent protection in this field of technology. Based on the European experience to now, however, it must be said that patent law is not the right place to legislate the consequences of the morality of an invention. An earlier version of this paper was presented at an international conference, “The Ethics of Intellectual Property Rights and Patents,” held in Warsaw, Poland on 23–24 April, 2004.     

如何推进儒教伦理与基督教伦理的融合

本文旨在阐明儒教伦理与基督教伦理在中国现代文化语境和社会场景中的确切含义,探讨克服儒教伦理与基督教伦理之间对立特征之有效途径,强调要从重叙传统和社会实践两个层面推动儒教伦理与基督教伦理的融合。     

Development of a Tissue Engineered Heart Valve for Pediatrics: A Case Study in Bioengineering Ethics

The following hypothetical case study was developed for bioengineering students and is concerned with choosing between two devices used for development of a pediatric tissue engineered heart valve (TEHV). This case is intended to elicit assessment of the devices, possible future outcomes, and ramifications of the decision making. It is framed in light of two predominant ethical theories: utilitarianism and rights of persons. After the case was presented to bioengineering graduate students, they voted on which device should be released. The results revealed that these bioengineering students preferred the more reliable (and substantially more expensive) design, though this choice precludes the majority of the world from having access to this technology. This case is intended to examine and explore where the balance lies between design, cost, and adequate distribution of biomedical devices.     

Better Never to Have Been Born

The pro‐life paradox, as I call it, begins with a single claim endorsed by many American Christians: infants and young children are innocent in the sight of God because they cannot yet take responsibility for their spiritual well‐being. With this in mind, I argue that pro‐life believers have unwittingly fallen victim to a theological paradox in which their attempts to save the earthly lives of unborn children make it theoretically possible for said children to die an eternal death. On the one hand, many Christians trust in an eventual spiritual reckoning where God will separate the “sheep” from the “goats” (see Matthew 25:31–46), ushering the former into heaven while damning the latter to hell. However, those who cannot yet repent and seek salvation are not blamed for their spiritual failings. If they die, they go to heaven because they are too young and intellectually immature to know any better. But if dead children are spiritually blameless, then abortion practitioners have perversely and paradoxically saved millions of unborn souls by removing human volition (and thus damnation itself) from the equation and by making it possible for the unborn to experience the joys of heaven without the temptations of earth.     

五个层面的挑战与三大理论难题——试论基因伦理

基因伦理的挑战在基因-检测、基因-治疗、基因-生殖、基因-克隆、基因-生态等五个层面展开,大致包括保护基因隐私、防止基因歧视,生殖细胞能否基因治疗,辅助生殖是否“扮演上帝”,克隆人,转基因的安全性等内容。同时,提出了基因决定论、实体论和主观论以及基因伦理走向何处等理论难题,需要认真研究和讨论。     

On Using Ethical Theories to Teach Engineering Ethics

Many engineering ethics classes and textbooks introduce theories such as utilitarianism and Kantianism (and most others draw from these theories without mentioning them explicitly). Yet using ethical theories to teach engineering ethics is not devoid of difficulty. First, their status is unclear (should one pick a single theory or use them all? does it make a difference?) Also, textbooks generally assume or fallaciously ‘prove’ that egoism (or even simply accounting for one’s interests) is wrong. Further, the drawbacks of ethical theories are underestimated and the theories are also otherwise misrepresented to make them more suitable for engineering ethics as the authors construe it, viz. the ‘moral reasoning’ process. Stating in what various theories disagree would allow the students to frame the problem more productively in terms of motive–consequence or society–individual dichotomies rather than in terms of Kant–utilitarian.     

萨顿的新人文主义及其意义

萨顿提出的新人文主义观,分析批判了科学与人文的分裂对立,指出科学人性化是科学与人文融合的方法,其人性化的科学现有利于我们今天深度解读、审视医学的人性化,张扬价值理性,在实践中克服目前医学异化的倾向,开掘医学和人文融合的路径,实现医学人性化的真正回归。     

Motivation and engagement in diverse performance settings: Testing their generality across school,university/college,work, sport,music, and daily life

In the light of recent calls for more integrative approaches to theorizing and measurement in motivation and engagement research, the present study assesses the generality of key motivation and engagement constructs across seven performance domains: elementary school (N = 624), high school (N = 21,579), university/college (N = 420), work (N = 637), music (N = 224), sport (N = 204), and daily life (N = 249). Based on domain specific adaptations of the Motivation and Engagement Scale, multi-group confirmatory factor analyses (CFAs) tested invariance across the seven domains. First and higher order multi-group CFAs demonstrated broad invariance in factor loadings (in particular), factor correlations/variances, and uniquenesses across performance domains. Taken together, the present data support the hypothesized generality of key motivation and engagement constructs. Findings hold implications for pragmatic, statistical, substantive, and intervention considerations in motivation and engagement research and also for research into cognate constructs in personality psychology more generally.     

Factorial validation and measurement invariance of the French version of the multidimensional competitive orientation inventory (FVMCOI) in the sport field

IntroductionLittle is known about the importance of the adaptive, maladaptive and neutral facets of competitive orientations among French athletes.ObjectiveThe aim of this study is to test the factorial validation and measurement invariance of the French version of the multidimensional competitive orientation inventory (FVMCOI) from the original version (MCOI, Orosz et al., 2018), which included 12 items and four factors (i.e., hypercompetitive orientation, self-developmental competitive orientation, anxiety-driven competition avoidance, and lack of interest toward competition).MethodA series of three complementary studies was carried out with a total sample of 891 competitors.ResultsFollowing cross-cultural validation methods a preliminary version of the FVMCOI was constructed and the clarity of its items was established (study 1). Then, exploratory structural equation modeling (ESEM) confirmed that the four-factor model for the FVMCOI was factorially valid, and consistent with the model of the original version. As such, the multiple-group invariance tests showed that the FVMCOI was partially invariant across both age and gender and fully invariant across type of sport, level of competition and over time (study 2). Finally, the concurrent validity of the FVMCOI was demonstrated through its expected relationships with achievement goals, competitive aggressiveness and anger in sport (study 3).ConclusionThe establishment of the FVMCOI extends the research in sport psychology by allowing an extensive psychometric study of the MCOI in the sport domain and providing deeper insights into the healthy, unhealthy, and neutral nature of competitive orientation in this context. The FVMCOI's potential practical applications in sport context, with some limitations and perspectives of this study, are also discussed.     

Ethical and Regulatory Considerations for Using Social Media Platforms to Locate and Track Research Participants

As social media becomes increasingly popular, human subjects researchers are able to use these platforms to locate, track, and communicate with study participants, thereby increasing participant retention and the generalizability and validity of research. The use of social media; however, raises novel ethical and regulatory issues that have received limited attention in the literature and federal regulations. We review research ethics and regulations and outline the implications for maintaining participant privacy, respecting participant autonomy, and promoting researcher transparency when using social media to locate and track participants. We offer a rubric that can be used in future studies to determine ethical and regulation-consistent use of social media platforms and illustrate the rubric using our study team’s experience with Facebook. We also offer recommendations for both researchers and institutional review boards that emphasize the importance of well-described procedures for social media use as part of informed consent.