Object localisation and frames of reference

In this paper, we explore which spatial frames of reference, egocentric or allocentric, are used to locate objects either in relation to ourselves (i.e. subject-to-object localisation) or to other objects (i.e. object-to-object localisation). In particular, we wanted to know whether the same or different frames of reference are used in these two different kinds of localisation after learning the environment in an egocentric way. Egocentric frames of reference are determined by the position of the person in relation to the spatial layout, whereas allocentric frames of reference are centred on the environment or on objects, independent of a persons position. We hypothesised that subject-to-object localisation is based on egocentric spatial representations, whereas object-to-object localisation is based on allocentric spatial representations. Participants were asked to study eight common objects, placed in a circle. Next, half of the participants had to point to an object in relation to their imagined position (egocentric condition) and the other half to an object in relation to another object (allocentric condition). The overall results show no difference between subject-to-object and object-to-object localisation. In both cases, access to positions corresponding to the front/back body axis was facilitated, in terms of both latency and error. Moreover, participants were able to retrieve objects positions better from the perspective from which they had learned the spatial array than from new perspectives. These results support the conclusion that egocentric coordinates, which are selected on the basis of our body-centred experience of the environment, define spatial representations underlying both subject-to-object and object-to-object localisation.     

Children's use of geometric information in mapping tasks

Accumulating evidence, particularly from research using the disorientation technique, demonstrates early sensitivity to geometric properties of space. However, it is not known whether children can use geometric cues to interpret a map. The current study examined how 3- to 6-year-olds use geometric features of layouts in solving mapping tasks. Children were asked to identify a target location in a layout shaped as an isosceles triangle by using information provided in a picture of that layout. Performance depended on whether the shape was presented explicitly or needed to be inferred. Younger participants performed better when the triangle was formed by continuous connected lines than when it was formed by separate objects. Performance also depended on the type of geometric cues available. Children found it easier to establish mapping for targets located in the unique corner of the triangle than for targets located in equal-sized corners. Overall, the findings reveal both a remarkable early ability to use geometric information in mapping and limits in this ability.     

Preparing for perception and action (I): the role of grouping in the response-cuing paradigm

Human skilled behavior requires preparatory processes that selectively make sensory and motor systems more efficient for perceiving the upcoming stimulus and performing the correct action. We review the literature concerning these preparatory processes as studied by response-cuing paradigm, and propose a model that accounts for the major findings. According to the Grouping Model, advance or precue information directs a dynamic process of subgroup making-that is, a process of stimulus- and response-set reconfiguration-whereby the internal representation of the task is simplified. The Grouping Model assigns a critical role to the unit of selection, with Gestalt factors and interresponse dependencies mediating the formation and strength of stimulus and response subgroups. In a series of five experiments, we manipulated perceptual and motoric grouping factors, and studied their independent and interactive effects on the pattern of precuing benefits. Generally, the results were consistent with the Grouping Model's account of response-cuing effects.     

Changing perspective within and across environments

Perspective change within a single environment is a slow and effortful process. However, little research has addressed perspective change across multiple environments. Using a task-set switching paradigm, subjects judged spatial relationships between target locations from differing perspectives. Response times were longer when successive trials probed different perspectives. However, this cost was greater when perspective was changed within a single environment compared to when it was changed across two environments. This result indicates that the processing of perspective change, and perhaps general spatial reasoning, differs in these two cases. Implications for theories of perspective change and environmental knowledge are discussed.     

Children with developmental coordination disorder (DCD) and their ability to disengage ongoing attentional focus: more on inhibitory function

Children with developmental coordination disorder (DCD), along with their Control counterparts, completed two endogenous, spatial precue tasks. When the precue arrow was informative (.80) with respect to target location, the spatial precue effect results demonstrated that children with DCD take significantly longer than Control individuals to volitionally disengage (inhibit) attention from an endogenously cued location (i.e., a disengagement inhibition deficit). When the precue was uninformative (.25), we found, contrary to a common assumption, that the precue arrow automatically moved attention in the direction of the arrow, and, in addition, that DCD children may also be less able to inhibit the precued-induced urge to move attention (i.e., an initiation inhibition deficit). This type of inhibitory difficulty was also indicated for manual response inclinations produced on catch trials. Overall, DCD children appeared to have an elevated difficulty suppressing the initiation of incorrect, stimulus-provoked movement urges, be they manual or attention in nature.     

Cholinergic modulation of the hippocampus during encoding and retrieval

The present experiments were aimed at determining whether acetylcholine (ACh) plays a role in encoding and retrieval of spatial information using a modified Hebb-Williams maze. In addition, the present experiments tested two computational models of hippocampal function during encoding and retrieval using a maze sensitive to hippocampal disruption. Thirty male, Long-Evans rats served as subjects. Chronic cannulae were implanted bilaterally into the CA3 (n=26) and CA1 (n=5) subregions of the hippocampus. Rats were tested using a modified Hebb-Williams maze. In the first experiment, rats were injected with either saline or scopolamine hydrobromide 10 min before testing for each day. The number of errors made per day per group was used as the measure of learning. Encoding was assessed by the average number of errors made on the first five trials of Day 1 compared to the last five trials of Day 1, whereas the average number of errors made on the first five trials of Day 2 compared to the last five trials of Day I was used to assess retrieval. No deficit was found for the saline group. The scopolamine group showed a deficit in encoding, but not retrieval. In the second experiment, rats were injected with either saline or physostigmine 10 min before testing each day. In contrast to the scopolamine groups, the physostigmine group showed a deficit in retrieval, but not encoding. To test whether the retrieval deficit was due to a disruption in storage or gaining access to the information two groups of rats received either saline on Day 1 and physostigmine on Day 2 or physostigmine on Day 1 and saline on Day 2. In addition, one group received physostigmine immediately after testing on Day 1. Data indicate that physostigmine causes a disruption of retrieval by means of a disruption in consolidation process. In conclusion, the cholinergic antagonist, scopolamine, disrupts encoding in both CA3 and CA1 subregions of the hippocampus. Furthermore, the cholinesterase inhibitor, physostigmine, boosts ACh action during a time when cholinergic levels need to decline for proper consolidation.     

Estrogen modulates place learning through estrogen receptors in the hippocampus

Moderate elevations in circulating estradiol enhance learning in tasks that tap place learning strategies such as those requiring the use of extramaze cues. Use of place learning strategies is particularly impaired by damage to the hippocampus, a structure shown to be sensitive to estrogen treatments. We have shown that direct estrogen infusions into the dorsal hippocampus, and not the dorsolateral striatum, enhance place learning, suggesting that the hippocampus may be an important modulatory site for the effects of estrogen on place learning. The current experiment tested whether the hippocampus is indeed a critical site of estrogen modulation through classical estrogen receptors. Young adult female Sprague-Dawley rats were ovariectomized for 21 days and given systemic injections (0.1 ml) of sesame oil (OIL) or 10 microg of 17beta-estradiol-benzoate (E2), 48 and 24 h before being trained on a place task. Twenty-four hours prior to the first systemic injection, separate groups of rats received bilateral hippocampal implants of either the antiestrogen ICI 182,780 (ICI) or cholesterol vehicle. Implants were maintained until and throughout training. Intrahippocampal ICI reversed the enhancement in place learning seen with systemic E2 treatment. Unexpectedly, intrahippocampal ICI in OIL-treated rats also enhanced place learning. These data suggest that ICI may have some mixed agonist and antagonist effects in the hippocampus and that estrogen enhances place learning through activation of estrogen receptors located in the hippocampus.