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261.
CagA蛋白是幽门螺杆菌最重要的毒力因子之一。目前已证实cagA基因存在东亚及西方两种亚型。幽门螺杆菌产生CagA蛋白,注入胃上皮细胞后在其羧基端EPIYA重复序列区进行酪氨酸磷酸化,进而与SHP-2酪氨酸磷酸化酶相互作用,参与上皮细胞的信号传导,导致细胞骨架结构的重排,引起细胞表面形状的改变和细胞动力的增强,造成细胞异常的增殖和运动,在胃癌的发生中起了主要作用。cagA基因的羧基端EPIYA重复序列被认为是区分东亚型和西方型菌株的分子标记,东亚型CagA与SHP-2亲和力大于西方型,最终影响着不同CagA 菌株感染的临床表现。  相似文献   
262.
自我验证与人际一致性:团队多样性利用的新视角   总被引:1,自引:0,他引:1  
全球化背景下组织构成正日趋多样化, 有效利用团队多样性的价值是组织成功的关键。以往的研究基于自我类化理论认为消除多样性负面效应的方法是追求高阶的群体认同。本文采用自我验证的视角, 提出团队成员的个人自我认知和社会自我认知得到他人验证能够促进人际一致性, 增强个体对群体的情感联结, 并可以最大化地发挥多样性的正面效应, 提升决策质量和团队效能。此外, 当团队分裂为小团体、联盟体和共同体等三种不同的亚群体类型时, 自我验证过程将呈现出不同的动态, 团队领导者需要采取针对性的领导方式来帮助成员获得自我验证的信息。  相似文献   
263.
Recent news reports have focused attention on dramatic instances of workplace violence—extreme acts of aggression in work settings. It is suggested here that such actions, while both tragic and frightening, are only a small part of a much larger problem of workplace aggression—efforts by individuals to harm others with whom they work or the organizations in which they are employed. The present study investigated two major hypotheses with respect to such aggression: 1) contrary to what media reports suggest, most aggression occurring in work settings is verbal, indirect, and passive rather than physical, direct, and active; 2) recent changes in many organizations (e.g., downsizing, increased workforce diversity) have generated conditions that may contribute to the occurrence of workplace aggression. A survey of 178 employed persons provided partial support for both predictions. Verbal and passive forms of aggression were rated as more frequent by participants than physical and active forms of aggression. In addition, the greater the extent to which several changes had occurred recently in participants' organizations, the greater the incidence of workplace aggression they reported. © 1996 Wiley-Liss, Inc.  相似文献   
264.
李同吉  桑标 《心理科学》2005,28(1):128-129,124
本文介绍了行动观的主要理论观点,认为个体有意识的自我发展和自我调节对于发展具有重大意义,进而阐述了自我观察、自我评价和自我调节的过程和机制。行动观克服了哲学的决定论和因果机制的局限,把发展的多样性和规律性统一起来,并有效地整合了文化和个体自身对于发展的作用。  相似文献   
265.
Training programs committed to the development of culturally sensitive family therapists must support dialogue that creates awareness of social structures promoting inequity and oppression. In order to facilitate meaningful conversations about issues of social justice educators have to critically examine their own philosophies and teaching methods to create a learning environment that promotes this dialogue for all students. This article outlines our philosophy of teaching and presents two core MFT graduate courses as examples of how issues of social justice can be valued in the didactic component of marital and family therapy (MFT) training.  相似文献   
266.
世界上存在着道德多元性,它表现为生命伦理学的实际道德分布的特征,它是使用人类胚胎作为干细胞来源的争论的根本原因。在世俗文化中,干细胞的使用甚至也会出现疑问。只以从传统的基督教道德直觉和期望的残留影响角度去理解这种现象。关于干细胞的争论反映了更深层次的文化错位。我们正生活在文化战争频发的年代。有必要对罗尔斯学派的关于公共讨论及理性的道德多元化给予重新的关注和评价。  相似文献   
267.
The European Journal of Social Psychology (EJSP), as the voice of the European Association of Social Psychology, aims to promote diversity and a distinctively ‘European’, more ‘social’, social psychology (SP). However, whether and how these objectives have been accomplished over time remains controversial. This article enters this debate, tracing the history of SP as depicted by EJSP publications, via two types of lexicometric analyses of all abstracts of the Journal (1971–2016). Themes, processes, methods, and their organisation in cycles and clusters over time, were identified and analysed. Regarding diversity, findings indicate that the publications reflect several of the new theoretical proposals that emerged over the years, but do not fully reflect the variety of perspectives and methods of the discipline. It further indicates that lately the ‘social’ is predominantly present in attention to pressing social issues, albeit the processes involved in them are mostly theorised at an individualistic level. This pattern suggests the importance of keeping open the quest for epistemological and methodological diversity, and of re-problematising what the ‘social’ in SP means. By contributing to mapping the history of SP, offering a more comprehensive and reflexive view for it, the present analyses also help in forging a stronger discipline.  相似文献   
268.
This study investigated relationships between national and ethnic identities in eleven countries of the Southern African Development Community (SADC). Ethnic versus national identification, experiences of unfair treatment of ethnic groups, and like versus dislike of out-group neighbours were investigated. Round 6 Afrobarometer surveys data from Botswana (n?=?1 200), Lesotho (n?=?1 200), Madagascar (n?=?1 200); Malawi (n?=?2 400), Mauritius (n?=?1 200), Mozambique (n?=?2 400), Namibia (n?=?1 200), South Africa (n?=?2 400), Tanzania (n?=?2 400), Zambia (n?=?1 200), and Zimbabwe (n?=?2 400) were utilised for the analysis. Majorities of respondents in most countries, especially in those with a dominant majority group, identified equally as much with the nation and ethnic group, or more with the nation. However, ethnic identities remain relevant despite nation-building strategies, even in relatively ethno-culturally homogeneous countries. Ethnic identity salience was enhanced by unfair treatment. Findings suggest recognition and accommodation of diversity to be a prospective strategy to foster stability and peace.  相似文献   
269.
本文建立基于IPO模型的团队多样性-冲突-绩效的权变模型。通过对国内外的112篇实证文章(n=9263)进行元分析,本文定量地梳理近年来团队多样性-团队冲突-团队绩效之间关系的研究文献,并重点考察团队冲突与团队绩效之间的调节变量。元分析结果发现:团队深层多样性是引起团队冲突的重要因素,表层多样性并不会显著增加团队冲突;与美国的研究不同,中国情境下任务冲突将显著降低团队绩效;被试类型、回收率、团队规模和团队冲突的不对称感知等变量调节团队冲突与团队绩效之间的关系。  相似文献   
270.
从内隐异质性的内涵维度及其效能机制, 包括内隐异质性作用于绩效的中间过程和情境因素、内隐异质性和外显异质性的交互作用、团队断裂带和内隐异质性的跨层次研究方面阐述了团队内隐异质性研究的最新成果和进展, 并在此基础上提出了未来研究的一个整合框架。未来的研究需要在内隐异质性内涵维度及其前因变量、内隐异质性的跨层次研究、团队断裂带及其与团队结果变量之间关系、社会网络背景下内隐异质性与团队绩效之间的关系等方面进一步探索。  相似文献   
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