Encoder Enhanced Atrous (EEA) Unet architecture for Retinal Blood vessel segmentation

The retinal blood vessel segmentation is required for continuously monitoring the blood vessel in most of the retinal disease diagnosis. Deep learning approaches are accepted as the promising techniques for biomedical image segmentation. In this paper, Encoder enhanced Atrous architecture is proposed for retinal blood vessel segmentation. The encoder section is enhanced by improving the depth concatenation process with the addition layers. The proposed architecture is evaluated on the publicly available databases DRIVE, STARE, CHASE_DB1 and HRF using metrics like accuracy, sensitivity, specificity, Dice coefficient, and Mathew’s correlation coefficient. The proposed architecture performs better compared to the conventional Unet architecture in terms of accuracy by 0.35% and 0.83% for DRIVE and STARE respectively. In terms of specificity and Dice score, the proposed architecture also shows improved results compared to the Unet architecture.     

Occlusions at event boundaries during encoding have a negative effect on infant memory

The present study investigated the importance of Event Boundaries for 16- and 20-month-olds’ (n = 80) memory for cartoons. The infants watched one out of two cartoons with ellipses inserted covering the screen for 3 s either at Event Boundaries or at Non-Boundaries. After a two-week delay both cartoons (one familiar and one novel) were presented simultaneously without ellipses while eye-tracking the infants. According to recent evidence a familiarity preference was expected. However, following Event Segmentation Theory ellipses at Event Boundaries were expected to cause greater disturbance of the encoding and hence a weaker memory trace evidenced by reduced familiarity preference, relative to ellipses at Non-Boundaries. The results suggest that overall this was the case, documenting the importance of Boundaries for infant memory. Furthermore, planned analyses revealed that whereas the same pattern was found when looking at the 20-month-old infants, no significant difference was found between the two conditions in the youngest age-group.     

中文阅读预视加工中的词频和预测性效应及其对词切分的启示:基于眼动的证据

研究采用眼动随动显示技术考察中文阅读预视加工中的词汇加工问题。前三项实验发现,剥夺预视加工的掩蔽条件、正确提示词n+1右侧边界的掩蔽条件以及不能提示词n+1右侧边界的掩蔽条件都不影响词频效应,说明中文读者对词n+1处文字的预视加工达不到词汇水平。实验4考察剥夺预视加工的掩蔽条件、提示词n+1右侧边界的掩蔽条件对预测性效应的影响,结果发现,剥夺预视加工完全消除预测性效应,提示词n+1右侧边界则减少预测性效应,说明对词汇的预期加工是中文读者切分词n+1的参考线索。综合4项实验结果可知,中文读者较难通过自下而上的文字识别切分词n+1,自上而下的词汇预期则是切分词n+1的加工形式。     

The use of probabilistic lexicality cues for word segmentation in Chinese reading

In an eye-tracking experiment we examined whether Chinese readers were sensitive to information concerning how often a Chinese character appears as a single-character word versus the first character in a two-character word, and whether readers use this information to segment words and adjust the amount of parafoveal processing of subsequent characters during reading. Participants read sentences containing a two-character target word with its first character more or less likely to be a single-character word. The boundary paradigm was used. The boundary appeared between the first character and the second character of the target word, and we manipulated whether readers saw an identity or a pseudocharacter preview of the second character of the target. Linear mixed-effects models revealed reduced preview benefit from the second character when the first character was more likely to be a single-character word. This suggests that Chinese readers use probabilistic combinatorial information about the likelihood of a Chinese character being single-character word or a two-character word online to modulate the extent of parafoveal processing.     

Learning to love the older consumer

This paper examines how and why marketing has largely ignored the older consumer and concentrated on younger targets. It explores some of the myths of the older consumer and through examining recent research in the USA and the UK makes a plea for accepting the older consumer as still very much in the main stream of marketing. It also explores how society constructs age and how older people may wish to see themselves. While age related myopia is unsatisfactory for both consumers and marketing, older consumers may express a wide range of identities, making them a potentially complex target for marketing. The paper suggests that more research is needed to explore the different motives and identities of these important consumers with a view to better meeting their needs in terms of appropriate products, messages and media. Copyright © 2001 Henry Stewart Publications.     

A randomized controlled trial of the effect of D-cycloserine on extinction and fear conditioning in humans

Previous research has shown that D-cycloserine (DCS) facilitates extinction of Pavlovian fear conditioning in rats and enhances exposure therapy in humans. The aim of this study was to test the effect of DCS on extinction of fear conditioning in humans. In three experiments, 238 participants were given either DCS (50 or 500 mg) or placebo 2-3 h before extinction training following a differential shock conditioning paradigm. Clear extinction and recovery (return of fear) effects were observed on both skin conductance and self-reported shock expectancy measures in three studies. DCS had no influence on these effects. The same pattern was observed when the analysis was restricted to aware participants or to good conditioners, when fear-relevant cues (pictures of snakes) were used as the conditioned stimuli, or when analysis was restricted to heightened snake-fearful participants. These results suggest that DCS may not enhance the extinction, or prevent the recovery, of learned fear in a differential Pavlovian conditioning paradigm in humans. Further experimental research is needed to better understand the mechanisms underlying the therapeutic effects of DCS.     

Verbal, behavioural and physiological assessment of the generalization of exposure-based fear reduction in a spider-anxious population

Clinical fear of spiders was assessed in 39 patients before and after exposure treatment and at a 3-month follow-up. The assessment included behavioral, physiological and self-report measures. Some patients were tested in the treatment context (group Same), while others were tested in a different context (group Different). Both groups demonstrated a significant fear reduction from pre- to post-treatment in all measures, which persisted at the 3-month follow-up. Contrary to our expectations, no clear difference was observed between the groups at any moment. However, a 1-year follow-up test of the self-report measure revealed a return of fear in group Same, but not in group Different. These results show (1) that the effects of exposure treatment persisted over contexts and time in the short term, and (2) that conducting treatment and tests in different contexts enhanced efficiency of exposure treatment in the long term.     

Are Asians forgetful? Perception, retention, and recall in episodic remembering

Cross-cultural studies have shown that Asians exhibit less accessibility to episodic memories than Euro-Americans. This difference is often attributed to differential cognitive and social influences on memory retention, although there have been no empirical data concerning the underlying mechanism. Three studies were conducted to examine encoding and retention processes that may underlie the cultural difference in episodic recall. While Asians recalled fewer personal event episodes than Euro-Americans across different retention intervals, the two groups showed similar forgetting functions over time (Study 1). Asians also recalled fewer episodes of fictional events than Euro-Americans when the retention interval was kept to a minimum (Study 2). Finally, Asians perceived fewer discrete episodes than Euro-Americans when reading events in a narrative text (Study 3). Collectively, these findings suggest that the cultural difference in episodic recall may not be a mere consequence of memory retention but culture-specific perceptual processing and encoding. They have great theoretical, developmental, and clinical relevance.     

Recognizing speech under a processing load: Dissociating energetic from informational factors

Effects of perceptual and cognitive loads on spoken-word recognition have so far largely escaped investigation. This study lays the foundations of a psycholinguistic approach to speech recognition in adverse conditions that draws upon the distinction between energetic masking, i.e., listening environments leading to signal degradation, and informational masking, i.e., listening environments leading to depletion of higher-order, domain-general processing resources, independent of signal degradation. We show that severe energetic masking, such as that produced by background speech or noise, curtails reliance on lexical-semantic knowledge and increases relative reliance on salient acoustic detail. In contrast, informational masking, induced by a resource-depleting competing task (divided attention or a memory load), results in the opposite pattern. Based on this clear dissociation, we propose a model of speech recognition that addresses not only the mapping between sensory input and lexical representations, as traditionally advocated, but also the way in which this mapping interfaces with general cognition and non-linguistic processes.